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The map label for this gene is dnaQ [H]

Identifier: 167623805

GI number: 167623805

Start: 2248372

End: 2249100

Strand: Direct

Name: dnaQ [H]

Synonym: Shal_1875

Alternate gene names: 167623805

Gene position: 2248372-2249100 (Clockwise)

Preceding gene: 167623803

Following gene: 167623806

Centisome position: 43.02

GC content: 45.82

Gene sequence:

>729_bases
ATGAATATTGTTTCAAGCGCGAAGCGACAAATTATTCTCGATACCGAAACCACAGGTATGAACCAATCGAGCGGTCCAAT
TTATTTGGGCCATAGGATCATTGAAATTGGTTGTGTCGAAGTAATAAACCGCCGTTTAACGGGCCGCCATTATCATGAGT
ACATTAATCCGCAACAGCCGATTGATGAAGAAGCGATTGCCGTTCACGGTATAACCAATGAGTTTGTGGCGGATAAACCA
AAGTTTCATGAAATTGCACAAAGCTTTATTGAGTTTATCGATGGCGCAGAGATCGTGGCACATAACGCTAACTTCGACGT
TAGCTTTATGGATCATGAATTTTCGATGTTGCAGCCGCGGGGGCCAAAGACGGCTGATATCTGTCAGATCCTAGATTCGC
TCGCAATCGCTAAACATTTACACCCTGGCCAAAAGAATAACTTGGACGCCTTGTGTAAGCGTTATGGTATCGATAACTCG
GCCCGTGATCTCCACGGCGCTTTACTCGATGCCGAGATTTTGGCTGACGTATACCTGTTGATGACAGGTGGTCAAACGAA
ATTTAACCTTTCAAGTGAAAAAGCAGGACAAGAGGGCGGTGGTATTCATCGCCTAAGTGCGGATAGATCAAAACTTAAAG
TGATCGCGGCATCGGCCGATGAACTGATAAGACACGAAGAGCGGCTCGACTTAGTCGCAAAATCAGGACAATGCCTCTGG
CGCGGATAA

Upstream 100 bases:

>100_bases
GATAGAGATCTGTTTCAGTCCAGTCATCAAGTTGCTACCATAGCTATAATTGCTGGGCGAGTATACCCAAAAAATTTAAC
TGAGAAATGCATAAATTCAT

Downstream 100 bases:

>100_bases
ACGTCATTTTATGAGTCTCTCTATGATTAGAAGAGTTAAATCTCTAACGGTTTTCTTAATTTGTTATTTTTTAGTGAGCA
GCGCAGCCTTGGCTGATGTC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNIVSSAKRQIILDTETTGMNQSSGPIYLGHRIIEIGCVEVINRRLTGRHYHEYINPQQPIDEEAIAVHGITNEFVADKP
KFHEIAQSFIEFIDGAEIVAHNANFDVSFMDHEFSMLQPRGPKTADICQILDSLAIAKHLHPGQKNNLDALCKRYGIDNS
ARDLHGALLDAEILADVYLLMTGGQTKFNLSSEKAGQEGGGIHRLSADRSKLKVIAASADELIRHEERLDLVAKSGQCLW
RG

Sequences:

>Translated_242_residues
MNIVSSAKRQIILDTETTGMNQSSGPIYLGHRIIEIGCVEVINRRLTGRHYHEYINPQQPIDEEAIAVHGITNEFVADKP
KFHEIAQSFIEFIDGAEIVAHNANFDVSFMDHEFSMLQPRGPKTADICQILDSLAIAKHLHPGQKNNLDALCKRYGIDNS
ARDLHGALLDAEILADVYLLMTGGQTKFNLSSEKAGQEGGGIHRLSADRSKLKVIAASADELIRHEERLDLVAKSGQCLW
RG
>Mature_242_residues
MNIVSSAKRQIILDTETTGMNQSSGPIYLGHRIIEIGCVEVINRRLTGRHYHEYINPQQPIDEEAIAVHGITNEFVADKP
KFHEIAQSFIEFIDGAEIVAHNANFDVSFMDHEFSMLQPRGPKTADICQILDSLAIAKHLHPGQKNNLDALCKRYGIDNS
ARDLHGALLDAEILADVYLLMTGGQTKFNLSSEKAGQEGGGIHRLSADRSKLKVIAASADELIRHEERLDLVAKSGQCLW
RG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=242, Percent_Identity=56.198347107438, Blast_Score=278, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26821; Mature: 26821

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVSSAKRQIILDTETTGMNQSSGPIYLGHRIIEIGCVEVINRRLTGRHYHEYINPQQP
CCCCCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
IDEEAIAVHGITNEFVADKPKFHEIAQSFIEFIDGAEIVAHNANFDVSFMDHEFSMLQPR
CCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHCCCC
GPKTADICQILDSLAIAKHLHPGQKNNLDALCKRYGIDNSARDLHGALLDAEILADVYLL
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHE
MTGGQTKFNLSSEKAGQEGGGIHRLSADRSKLKVIAASADELIRHEERLDLVAKSGQCLW
EECCCCEEECCHHHCCCCCCCEEEECCCCHHEEEEECCHHHHHHHHHHHHHHHCCCCEEE
RG
CC
>Mature Secondary Structure
MNIVSSAKRQIILDTETTGMNQSSGPIYLGHRIIEIGCVEVINRRLTGRHYHEYINPQQP
CCCCCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
IDEEAIAVHGITNEFVADKPKFHEIAQSFIEFIDGAEIVAHNANFDVSFMDHEFSMLQPR
CCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHCCCC
GPKTADICQILDSLAIAKHLHPGQKNNLDALCKRYGIDNSARDLHGALLDAEILADVYLL
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHE
MTGGQTKFNLSSEKAGQEGGGIHRLSADRSKLKVIAASADELIRHEERLDLVAKSGQCLW
EECCCCEEECCHHHCCCCCCCEEEECCCCHHEEEEECCHHHHHHHHHHHHHHHCCCCEEE
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]