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The map label for this gene is fadR

Identifier: 167623772

GI number: 167623772

Start: 2198583

End: 2199302

Strand: Direct

Name: fadR

Synonym: Shal_1842

Alternate gene names: 167623772

Gene position: 2198583-2199302 (Clockwise)

Preceding gene: 167623769

Following gene: 167623775

Centisome position: 42.06

GC content: 44.17

Gene sequence:

>720_bases
ATGATCATCAATGCTAAAGGTCCTGCAAGTTTTGCAGAGAAATATATTGTACGATCCATCTGGGAAAATAAGTTTCCGCC
AGGCTCTATTCTGCCCGCAGAACGTGAGCTTTCAGAGTTGATTGGTGTGACCCGTACTACGCTACGTGAAGTATTACAGC
GTTTGGCTCGTGATGGATGGTTGACTATTCAACACGGTAAACCGACCAGAGTAAATAATTTCTGGGAAACTTCAGGTTTA
AACATCCTCGAGACCATTGCCGAGCTTAACCCTGACGGTTTCCCTGAACTAGTAGACCAATTGCTATCGGCACGAAGCAG
TGTCAGTGCCATTTACTTTAGAGGCGCAATTCGCAATAGTCCTGATGAAGCCGTGGTCGCATTGGCTAATATCAATGAGC
TTGAAGATACTGCACAGGCCTATGCTGACTTTGACTACGCGTTACAACACACCTTGGCATTTTCGTCAGGTAATCCACTT
TATGTTTTGATCCTAAACGGATTTAAAGGCTTGTATAGCAGAGTGGGGCGTTACTATTTTTCAAGTGCTGAAGCTCGTGC
CTTGGCGATGGATTTTTATAAGCAGTTGCAGCAACTTGCTATCGATAAAAACTACACCGATGTACCTGCGTTGATGCGTA
CATATGGGATCAATAGTGGTGTTATGTGGCAGAGTTTGCGTGATGATATGCCTGTAGAGTTAGGTCATTCAGATACGTAA

Upstream 100 bases:

>100_bases
CACATAGACATCGTCGAATAGCTCTGTTTTGGTTTTCATTTTTCGCGGCTCTGGTATGATCTGTATTAGAACAACACTAA
CAATTGGGTAGAGTAGGTTA

Downstream 100 bases:

>100_bases
GTCACATGAATCATCTGTTTTAAAAAAGAAAGCCATCGTTAAGATGGCTTTTTTGTTTTTAATGTTCTGGGCTAGTTATT
GGACTACAGATCAAAGCGAT

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNSPDEAVVALANINELEDTAQAYADFDYALQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVELGHSDT

Sequences:

>Translated_239_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNSPDEAVVALANINELEDTAQAYADFDYALQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVELGHSDT
>Mature_239_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNSPDEAVVALANINELEDTAQAYADFDYALQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVELGHSDT

Specific function: Multifunctional regulator of fatty acid metabolism

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787436, Length=234, Percent_Identity=59.8290598290598, Blast_Score=302, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FADR_SHEHH (B0TRI9)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674066.1
- ProteinModelPortal:   B0TRI9
- SMR:   B0TRI9
- GeneID:   5903775
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1842
- HOGENOM:   HBG296777
- OMA:   IVRSIWE
- ProtClustDB:   PRK04984
- BioCyc:   SHAL458817:SHAL_1842-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00696
- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345
- TIGRFAMs:   TIGR02812

Pfam domain/function: PF07840 FadR_C; PF00392 GntR; SSF48008 FadR_C

EC number: NA

Molecular weight: Translated: 26788; Mature: 26788

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDEAVVALANINELEDTAQAYADFDYALQHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVELGHSDT
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDEAVVALANINELEDTAQAYADFDYALQHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVELGHSDT
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA