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The map label for this gene is speA

Identifier: 167623733

GI number: 167623733

Start: 2155434

End: 2157347

Strand: Direct

Name: speA

Synonym: Shal_1803

Alternate gene names: 167623733

Gene position: 2155434-2157347 (Clockwise)

Preceding gene: 167623727

Following gene: 167623734

Centisome position: 41.24

GC content: 45.09

Gene sequence:

>1914_bases
ATGAGCAATTGGTCTATTGATGATGCACGCGCAAGTTATAACGTAAATCACTGGAGCCAAGGACTTTACGGCATTAGCGA
TGATGGAGAAGTGACTGTGTCACCGGATCCAAGCCGCCCAGAATGTAAGATTGGTTTAAACGAAATGGCAAAAGACATGG
TTAAGTCGGGCGTGGCTTTACCTGTTCTGGTTCGTTTTCCGCAAATTTTACATCATAGAGTAAATAGTCTGTGTCAGGCA
TTTAATCAGGCGATTCAAAAGTATCAATATGAAAATGATTACTTGCTGGTATACCCGATTAAAGTAAACCAACAGCAAAC
GGTTGTTGAAGAGATCCTTGCTAGCCAAGTAGAAAAAGAAGTGCCACAGCTAGGTCTAGAAGCGGGTAGTAAGCCTGAGC
TAATGGCTGTTTTGGCGATGGCACAAAAGGCGAGCTCTGTCATCATTTGTAATGGTTACAAAGATAAAGAGTACATTCGA
CTTGCATTGATAGGTGAAAAGCTGGGTCACAAGGTATATATCGTCCTTGAAAAAATATCTGAGCTTAAAGTCGTACTTGA
GCAAGCTAAAGAGCTAGGTGTTACACCTCGCCTCGGTCTGCGCGTGCGTCTTGCGTTCCAAGGCAAGGGGAAATGGCAGG
CAAGCGGTGGCGAGAAGTCTAAGTTTGGCCTGAGTGCTGCTCAAGTATTACAAGTGATTACCTCTCTCAAGCAAGAAAAT
ATGCTTGATTCGTTAGAGCTACTGCATTTCCATTTAGGTTCGCAAATCGCCAATATCCGCGATATTCGCCAAGGGGTGAG
TGAAGCGGGCCGTTTCTATTGTGAACTGATGAAGCTTGGTGCAAACGTTAAGTGTTTCGATGTCGGCGGTGGTCTAGCGG
TTGATTATGATGGTACTCGAAGCCAAAGTAGCCATTCAATGAACTACGGCCTGACCGAGTACGCCAACAATATCGTCAGT
GTGTTGACCGATATGTGCAAAGAATATGAGCAGCCGATGCCGAGAATTATCTCTGAGTCTGGCCGTTACTTGACTGCACA
TCACGCGGTATTGCTAACTGACGTGATTGGTACTGAAGCGTATAAGCCAGAAGATATTCAACCGCCAGCTGAAGATGCGC
CTCAGTTACTGCACAATATGTGGCAGTCTTGGGTTGAAGTCAGTGGTAAAGCTGATCAGCGTGCGCTAATTGAGATCTTC
CATGACTGTCAGAGTGATTTAACAGAAGTGCATTCGCTGTTTGCTGTTGGCCAGGTAGGTCTTGCTGAGCGCGCGTGGGC
AGAGCAAGTTAACTTGCGCGTCTGTTATGAGCTACAAGGCAGCATGAGTGCTAAGTATCGCTTCCATAGACCGATTATCG
ACGAGTTAAATGAAAAGTTAGCCGATAAGTTCTTTGTTAACTTCTCTTTGTTCCAATCTCTACCTGATGCTTGGGGTATT
GATCAGGTATTCCCTGTGATGCCTTTGTCTGGTTTAGATAAGGCGCCAGAGAGCAGAGCGGTAATGTTAGACATTACTTG
TGACTCAGACGGTACAATCGATCAATATGTTGACGGTCAAGGTATTGAAACAACACTGCCAGTACCTGCTTGGACGCAAG
AGAGTCCATATCTGATAGGCTTCTTCCTTGTTGGTGCATATCAAGAGATCTTGGGTGACATGCATAACTTATTTGGCGAC
ACTAACTCGGCAGTTGTACGTTTAGATGAAGATGCGCGCACTAATGTTGAGTCAGTACTCGCTGGTGATACGGTTGCTGA
CGTGCTGCGCTATGTAAACCTAGATGCTGTATCGTTTATGAGAACCTATGAGGAGCTCGTTAATAAGCATATCGCAGAAG
ATGAGCGTGCTAATATTCTAGAAGAATTGCAGCTAGGCCTTAAGGGCTACACTTATCTAGAAGACTTCTCTTAA

Upstream 100 bases:

>100_bases
TAGGTCGATCAGAATTTACTGATTAAAATATTCGCAAGTTGATTGTAACCATAGTGATTCAGTCAGCTTAATTGAGTTAA
ATAGACAGGTTAGGACAAAT

Downstream 100 bases:

>100_bases
CAAAGTGGTGAGCAACGCGTAAGCGTTGTCACTAGGGTAAAAATAGCCTGTTTGCTATAACCAGCTTTAAGTTCGCTTGA
AGCTGGTTTTATTTTTAGTC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPECKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSLCQA
FNQAIQKYQYENDYLLVYPIKVNQQQTVVEEILASQVEKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIR
LALIGEKLGHKVYIVLEKISELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVITSLKQEN
MLDSLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGANVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVS
VLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWVEVSGKADQRALIEIF
HDCQSDLTEVHSLFAVGQVGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTIDQYVDGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRLDEDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS

Sequences:

>Translated_637_residues
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPECKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSLCQA
FNQAIQKYQYENDYLLVYPIKVNQQQTVVEEILASQVEKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIR
LALIGEKLGHKVYIVLEKISELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVITSLKQEN
MLDSLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGANVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVS
VLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWVEVSGKADQRALIEIF
HDCQSDLTEVHSLFAVGQVGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTIDQYVDGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRLDEDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
>Mature_636_residues
SNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPECKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSLCQAF
NQAIQKYQYENDYLLVYPIKVNQQQTVVEEILASQVEKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRL
ALIGEKLGHKVYIVLEKISELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVITSLKQENM
LDSLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGANVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVSV
LTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWVEVSGKADQRALIEIFH
DCQSDLTEVHSLFAVGQVGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPIIDELNEKLADKFFVNFSLFQSLPDAWGID
QVFPVMPLSGLDKAPESRAVMLDITCDSDGTIDQYVDGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGDT
NSAVVRLDEDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=636, Percent_Identity=55.3459119496855, Blast_Score=728, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_SHEHH (B0TQX3)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674027.1
- GeneID:   5902856
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1803
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- BioCyc:   SHAL458817:SHAL_1803-MONOMER
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC

EC number: =4.1.1.19

Molecular weight: Translated: 71121; Mature: 70989

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPECKIGLNEMAKDMVKSGVAL
CCCCCCCCHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCEECHHHHHHHHHHCCCCH
PVLVRFPQILHHRVNSLCQAFNQAIQKYQYENDYLLVYPIKVNQQQTVVEEILASQVEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRLALIGEKLGHKVYIVLEKIS
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEHHHHHH
ELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVITSLKQEN
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MLDSLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGANVKCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
SQSSHSMNYGLTEYANNIVSVLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHCCCC
YKPEDIQPPAEDAPQLLHNMWQSWVEVSGKADQRALIEIFHDCQSDLTEVHSLFAVGQVG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LAERAWAEQVNLRVCYELQGSMSAKYRFHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTIDQYVDGQGIETTLPVPAWTQESPYLIG
CHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCEECCCCCCCCCCCCEEH
FFLVGAYQEILGDMHNLFGDTNSAVVRLDEDARTNVESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
SNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPECKIGLNEMAKDMVKSGVAL
CCCCCCCHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCEECHHHHHHHHHHCCCCH
PVLVRFPQILHHRVNSLCQAFNQAIQKYQYENDYLLVYPIKVNQQQTVVEEILASQVEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRLALIGEKLGHKVYIVLEKIS
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEHHHHHH
ELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVITSLKQEN
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MLDSLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGANVKCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
SQSSHSMNYGLTEYANNIVSVLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHCCCC
YKPEDIQPPAEDAPQLLHNMWQSWVEVSGKADQRALIEIFHDCQSDLTEVHSLFAVGQVG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LAERAWAEQVNLRVCYELQGSMSAKYRFHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTIDQYVDGQGIETTLPVPAWTQESPYLIG
CHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCEECCCCCCCCCCCCEEH
FFLVGAYQEILGDMHNLFGDTNSAVVRLDEDARTNVESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA