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The map label for this gene is rrmA [H]

Identifier: 167623726

GI number: 167623726

Start: 2149058

End: 2149864

Strand: Direct

Name: rrmA [H]

Synonym: Shal_1796

Alternate gene names: 167623726

Gene position: 2149058-2149864 (Clockwise)

Preceding gene: 167623724

Following gene: 167623727

Centisome position: 41.12

GC content: 40.4

Gene sequence:

>807_bases
ATGATTTACCGTTGCCCCTTATGCCAGCAAGCTTTATCTAAAGAAGATAAAACTTGGTGTTGCCCGTCAAACCACCGATT
TGATTGCGCCAAAGAAGGTTACGTAAACCTGTTACCAGTGCAAAAGAAGAAGTCGAACGATCCTGGTGATAACAAAGAGA
TGATGTTCGCTAGACGAGAATTTCTTAATAAGGGTTATTATCAAGACTTAAGCGATAAAGTTAACCAGCTCGCTAATGAG
TACCTTGAAGGTGCGCGTTTTGGTTTAGATATAGGTTGCGGCGAAGGCTACTATTCTGATCGTCTAGTAGAAAGCTTACC
GAGTGACTTTAGCCTTTATGGTGTAGACATCAGTAAATCAGCACTTAAGTATGCTGCTAAGCGTTACCCTAATATTTCAT
TCAGCGTTGCAAGCGCATTTGATATGCCATTCCCTGATGATAGTTTTGACTTTATGCTACGCATTTACGCGCCATCATTA
GATGTAGAGCTTAAACGGGTAATCAAATCAGGCGGGATTTTAATTACCGTTTGTGCTGGACCGAGACATCACTTTGCACT
TAAAGAGCTTATCTATGATAACCCTAAAGAGCATACTGAGGACTCTTCTCAAATTGAGGGCTTCGAGTTAATCCATCAAG
AGAGAATAGAGCAGGAGCTAACGCTCGATGATGCTGCCGATATTGGTCACTTTTTAAAAATGACACCTTATAACTGGAAG
TTAACAGAAGAACAAAAATTAGCGTTAGCTAAATCAGGTCTGAGTTGTGAGTTAGATTTTAAGGTCGAAGTCTTCAGAGC
CTTATAA

Upstream 100 bases:

>100_bases
GAGTCAGTTCCTAGGTCTGCGTTTGACAAATTAATATCTGGCCATCTTTTACGTGTTACTTAAGTAGAGCGTTTAACCGT
GGCCTTTCGGAGATGAATAC

Downstream 100 bases:

>100_bases
ATCAATGGGTGCAGCTTGTCGGTTGTTTTTTAAGCGATTCTTGGTGGTTGAGTTTTAATTTATAGAATTTAATTTTTTGA
TCCATTTGGCAAGCTCTAGA

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MIYRCPLCQQALSKEDKTWCCPSNHRFDCAKEGYVNLLPVQKKKSNDPGDNKEMMFARREFLNKGYYQDLSDKVNQLANE
YLEGARFGLDIGCGEGYYSDRLVESLPSDFSLYGVDISKSALKYAAKRYPNISFSVASAFDMPFPDDSFDFMLRIYAPSL
DVELKRVIKSGGILITVCAGPRHHFALKELIYDNPKEHTEDSSQIEGFELIHQERIEQELTLDDAADIGHFLKMTPYNWK
LTEEQKLALAKSGLSCELDFKVEVFRAL

Sequences:

>Translated_268_residues
MIYRCPLCQQALSKEDKTWCCPSNHRFDCAKEGYVNLLPVQKKKSNDPGDNKEMMFARREFLNKGYYQDLSDKVNQLANE
YLEGARFGLDIGCGEGYYSDRLVESLPSDFSLYGVDISKSALKYAAKRYPNISFSVASAFDMPFPDDSFDFMLRIYAPSL
DVELKRVIKSGGILITVCAGPRHHFALKELIYDNPKEHTEDSSQIEGFELIHQERIEQELTLDDAADIGHFLKMTPYNWK
LTEEQKLALAKSGLSCELDFKVEVFRAL
>Mature_268_residues
MIYRCPLCQQALSKEDKTWCCPSNHRFDCAKEGYVNLLPVQKKKSNDPGDNKEMMFARREFLNKGYYQDLSDKVNQLANE
YLEGARFGLDIGCGEGYYSDRLVESLPSDFSLYGVDISKSALKYAAKRYPNISFSVASAFDMPFPDDSFDFMLRIYAPSL
DVELKRVIKSGGILITVCAGPRHHFALKELIYDNPKEHTEDSSQIEGFELIHQERIEQELTLDDAADIGHFLKMTPYNWK
LTEEQKLALAKSGLSCELDFKVEVFRAL

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=269, Percent_Identity=46.8401486988848, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30635; Mature: 30635

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYRCPLCQQALSKEDKTWCCPSNHRFDCAKEGYVNLLPVQKKKSNDPGDNKEMMFARRE
CCEECCHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
FLNKGYYQDLSDKVNQLANEYLEGARFGLDIGCGEGYYSDRLVESLPSDFSLYGVDISKS
HHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCCEEEECCHHHH
ALKYAAKRYPNISFSVASAFDMPFPDDSFDFMLRIYAPSLDVELKRVIKSGGILITVCAG
HHHHHHHHCCCCEEEHHHHCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCCCEEEEEECC
PRHHFALKELIYDNPKEHTEDSSQIEGFELIHQERIEQELTLDDAADIGHFLKMTPYNWK
CCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEE
LTEEQKLALAKSGLSCELDFKVEVFRAL
ECHHHHHHHHHCCCCEEEECHHHHHHCC
>Mature Secondary Structure
MIYRCPLCQQALSKEDKTWCCPSNHRFDCAKEGYVNLLPVQKKKSNDPGDNKEMMFARRE
CCEECCHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
FLNKGYYQDLSDKVNQLANEYLEGARFGLDIGCGEGYYSDRLVESLPSDFSLYGVDISKS
HHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCCEEEECCHHHH
ALKYAAKRYPNISFSVASAFDMPFPDDSFDFMLRIYAPSLDVELKRVIKSGGILITVCAG
HHHHHHHHCCCCEEEHHHHCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCCCEEEEEECC
PRHHFALKELIYDNPKEHTEDSSQIEGFELIHQERIEQELTLDDAADIGHFLKMTPYNWK
CCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEE
LTEEQKLALAKSGLSCELDFKVEVFRAL
ECHHHHHHHHHCCCCEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]