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The map label for this gene is wzb [C]

Identifier: 167623691

GI number: 167623691

Start: 2110054

End: 2110515

Strand: Direct

Name: wzb [C]

Synonym: Shal_1761

Alternate gene names: 167623691

Gene position: 2110054-2110515 (Clockwise)

Preceding gene: 167623687

Following gene: 167623692

Centisome position: 40.37

GC content: 44.81

Gene sequence:

>462_bases
GTGTTTGTATGTATGGGCAACATTTGTCGCTCTCCTTCGGCTGAGGCGATGTTTAGATTAAAAGCACGAGCAGCCCAGTT
AGACATTGAGATAGATTCGGCTGGGACGATTGCTTATCACCAAGGGCATTCACCGGATAAGCGCTCTATCGCTGCCGGTG
TTAAGCGAGGGTTGAGCTTTGATGGCATGAGAGCTAGGCAGGTTGAGCAAACTGACTTTGTCGATTTTGATTTGATATTA
GCGGCAGATGAGCAAAACTTGCAGGACTTAAAGCGTATATGCCCTAAGCTATATCAGTCTAAGCTGGTGCTTATTTTAGA
CTTCTGCGATTTCGCATCTAATGCAGCAATTTATACTGAGGTGCCAGACCCATATTATGGGGAGGGTGATGGTTTTGAGT
TGGTGCTAGATCTGCTCGATAATAGCTGCGAGCAACTGGTAAAACGTATTCAAATTAAATAG

Upstream 100 bases:

>100_bases
TTAATCGTCTGAATTTATTCGTCTTTACCTTAGCGTTATTGGGTCTATTTTTTGTGCTGATTGAGTGCTATGCTATTGAT
ATCAATGGGTTTAATGGTTT

Downstream 100 bases:

>100_bases
CAGCACTTAGCAGGTGTAGACTAGTTTCTACTAGATGTGCGGACTTTAGTTTTAGATTAAATTGATAGCTTAGATTTCTT
TCATATAAATTCGCGTGACA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MFVCMGNICRSPSAEAMFRLKARAAQLDIEIDSAGTIAYHQGHSPDKRSIAAGVKRGLSFDGMRARQVEQTDFVDFDLIL
AADEQNLQDLKRICPKLYQSKLVLILDFCDFASNAAIYTEVPDPYYGEGDGFELVLDLLDNSCEQLVKRIQIK

Sequences:

>Translated_153_residues
MFVCMGNICRSPSAEAMFRLKARAAQLDIEIDSAGTIAYHQGHSPDKRSIAAGVKRGLSFDGMRARQVEQTDFVDFDLIL
AADEQNLQDLKRICPKLYQSKLVLILDFCDFASNAAIYTEVPDPYYGEGDGFELVLDLLDNSCEQLVKRIQIK
>Mature_153_residues
MFVCMGNICRSPSAEAMFRLKARAAQLDIEIDSAGTIAYHQGHSPDKRSIAAGVKRGLSFDGMRARQVEQTDFVDFDLIL
AADEQNLQDLKRICPKLYQSKLVLILDFCDFASNAAIYTEVPDPYYGEGDGFELVLDLLDNSCEQLVKRIQIK

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=151, Percent_Identity=35.0993377483444, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI6005988, Length=151, Percent_Identity=34.4370860927152, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788375, Length=148, Percent_Identity=29.0540540540541, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081812, Length=150, Percent_Identity=27.3333333333333, Blast_Score=66, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=152, Percent_Identity=34.2105263157895, Blast_Score=101, Evalue=5e-23,
Organism=Drosophila melanogaster, GI78706770, Length=156, Percent_Identity=35.8974358974359, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706772, Length=156, Percent_Identity=35.8974358974359, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706766, Length=154, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78706768, Length=154, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78706764, Length=127, Percent_Identity=37.7952755905512, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17127; Mature: 17127

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVCMGNICRSPSAEAMFRLKARAAQLDIEIDSAGTIAYHQGHSPDKRSIAAGVKRGLSF
CEEEECCHHCCCCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCC
DGMRARQVEQTDFVDFDLILAADEQNLQDLKRICPKLYQSKLVLILDFCDFASNAAIYTE
CCCCCHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEE
VPDPYYGEGDGFELVLDLLDNSCEQLVKRIQIK
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MFVCMGNICRSPSAEAMFRLKARAAQLDIEIDSAGTIAYHQGHSPDKRSIAAGVKRGLSF
CEEEECCHHCCCCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCC
DGMRARQVEQTDFVDFDLILAADEQNLQDLKRICPKLYQSKLVLILDFCDFASNAAIYTE
CCCCCHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEE
VPDPYYGEGDGFELVLDLLDNSCEQLVKRIQIK
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]