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The map label for this gene is yeeO [C]

Identifier: 167623555

GI number: 167623555

Start: 1949185

End: 1950711

Strand: Direct

Name: yeeO [C]

Synonym: Shal_1624

Alternate gene names: 167623555

Gene position: 1949185-1950711 (Clockwise)

Preceding gene: 167623554

Following gene: 167623557

Centisome position: 37.29

GC content: 47.28

Gene sequence:

>1527_bases
ATGGCTGTAGCCAAGTTTGTACAGGGATCGATATTACGTCATATCTTAGTGATGAGTTCTACCGCTGCTATCGGTATTTC
GGCGCTGTTTGTGGTCGATTTATTAGATATTTTCTTCCTTAGTTTACTCGGGGAGCAAGAGCTGGCCGCAGCGGTAGGCT
ATGCTGGTACTATCTCATTTTTCACCACCTCTATTGGTATTGGTCTCTCTATTGCACTCGGTGCATTAGTGTCGCGCTCT
ATCGGCGCTAAAGAGACTGAAATAGCTAAGCGTTTGTTGCTAAACAGCTTAGTTGTGACCTTTTTGATTAGTGTTTTTGT
GGCCTTTACCATATACATGTTTATTCCAGAGCTCTTAAGTCTTGTAGGAGCCACTGGAAAAACCGCTGAACTTGCCGAGA
GTTATCTCAATATCCTTGTACCTTCCTTGCCGCTTATCTGCTTAGCCATGGCGCTCGGTAGTGCACTAAGAGCGGTCGGC
GATGCCAAGCTGTCGATGGTATCGACCTTAATCGGAGGCGGGGTGAATGCGGTGTTTGACCCGATTTTTATCTTCATGTT
TGCCATGGGGATAGAGGGCGCGGCAGTTGCCTCTGTTATGGCTCGATTTGCGGTATTTGCGGTTGCCGCTAAAGGTGTGG
TGGTTAAACATAACTTACTTGGCCGCTTTAATTTCGATCACTTTATCGAAGATCTTAAACCGATTTTCGCCATTGCCGGA
CCAGCGATGCTCACTAACGTGGCCACGCCTATCGGCAATGCCGTGGTGACTCGCGCTATCGCCGACTTTGGTGATAGTTA
TGTGGCGGGCTGGGCCATACTGGGCCGCCTTATTCCTGTGTCGTTCGGTATGATCTTCGCGCTATCGGGTGCCGTTGGGC
CTATCGTTGGCCAAAACTATGGCGCGCTGGAGTTTGAGCGAGTCAAAGAGTCATTAACCCGTGCTATTCAGTTTTGCACA
GCCTATGTACTGGGCGTGTCACTGCTGCTGTTCTTAACTCGTCACCAAATCGTCAGCGTGTTTGATATGCAAGGCGATGC
TGCAGAGCTGATCTTGTTTTTCTGCTCCTATATCGCAGTGTTCTTTATCTTCTCGGGTATTTTGTTTGTCGCTAACGCCT
CATTTAACAACTTAGGTAAGGCTAAGTATTCGACCCTGTTTAATGTCGGTAAGGCAACATTAGGCACCATTCCATTTGTG
TATTTTGGCGCACAGTGGGGGGGAGTCTATGGTGTGTTAATAGGGCAGGCAATCGGTTCGATTATCTTTGGCATTTTGGG
AGTGCTAGTGGCGTACCAGTTGGTAGACAAGGTGCAAACCATGACCGTTGCTGGGCTTTATGGAGCTAATATACCGAAAG
ATGAAGAGAAAACTGAGTTTGATGAGGAGTTAAGCTTAAGTAGCCAGAGTCCAATGTCGTCATCTTGTGCCAATATGGCC
ATGGTGAATGAAGAACAAGACTGTGAGGCCAGTAATGAAGTAGCTGAGCTTATTGGCGTAAAAGAAGATAACGCTTCAAC
CAAGTAA

Upstream 100 bases:

>100_bases
TGACAATAATGCACTTTACTGCGACCATTGTGGCAGCGAGTTAGAGACTGACTTGTAAATACTATCAATATAATGGATTA
GCCAAGGGCATCGAGGTGAT

Downstream 100 bases:

>100_bases
GCTCAATCAAACGATAAAAGTCGTGCAGAAACTCGGCTTAGAGATTAATTTGCCGACGCTGCTTTTTCTTCGTTCGCTTC
TACCGATGCGTCGTTAGTTG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MAVAKFVQGSILRHILVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRS
IGAKETEIAKRLLLNSLVVTFLISVFVAFTIYMFIPELLSLVGATGKTAELAESYLNILVPSLPLICLAMALGSALRAVG
DAKLSMVSTLIGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAAKGVVVKHNLLGRFNFDHFIEDLKPIFAIAG
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAILGRLIPVSFGMIFALSGAVGPIVGQNYGALEFERVKESLTRAIQFCT
AYVLGVSLLLFLTRHQIVSVFDMQGDAAELILFFCSYIAVFFIFSGILFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGAQWGGVYGVLIGQAIGSIIFGILGVLVAYQLVDKVQTMTVAGLYGANIPKDEEKTEFDEELSLSSQSPMSSSCANMA
MVNEEQDCEASNEVAELIGVKEDNASTK

Sequences:

>Translated_508_residues
MAVAKFVQGSILRHILVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRS
IGAKETEIAKRLLLNSLVVTFLISVFVAFTIYMFIPELLSLVGATGKTAELAESYLNILVPSLPLICLAMALGSALRAVG
DAKLSMVSTLIGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAAKGVVVKHNLLGRFNFDHFIEDLKPIFAIAG
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAILGRLIPVSFGMIFALSGAVGPIVGQNYGALEFERVKESLTRAIQFCT
AYVLGVSLLLFLTRHQIVSVFDMQGDAAELILFFCSYIAVFFIFSGILFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGAQWGGVYGVLIGQAIGSIIFGILGVLVAYQLVDKVQTMTVAGLYGANIPKDEEKTEFDEELSLSSQSPMSSSCANMA
MVNEEQDCEASNEVAELIGVKEDNASTK
>Mature_507_residues
AVAKFVQGSILRHILVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRSI
GAKETEIAKRLLLNSLVVTFLISVFVAFTIYMFIPELLSLVGATGKTAELAESYLNILVPSLPLICLAMALGSALRAVGD
AKLSMVSTLIGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAAKGVVVKHNLLGRFNFDHFIEDLKPIFAIAGP
AMLTNVATPIGNAVVTRAIADFGDSYVAGWAILGRLIPVSFGMIFALSGAVGPIVGQNYGALEFERVKESLTRAIQFCTA
YVLGVSLLLFLTRHQIVSVFDMQGDAAELILFFCSYIAVFFIFSGILFVANASFNNLGKAKYSTLFNVGKATLGTIPFVY
FGAQWGGVYGVLIGQAIGSIIFGILGVLVAYQLVDKVQTMTVAGLYGANIPKDEEKTEFDEELSLSSQSPMSSSCANMAM
VNEEQDCEASNEVAELIGVKEDNASTK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=481, Percent_Identity=22.037422037422, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 53753; Mature: 53621

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAKFVQGSILRHILVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHH
FTTSIGIGLSIALGALVSRSIGAKETEIAKRLLLNSLVVTFLISVFVAFTIYMFIPELLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGATGKTAELAESYLNILVPSLPLICLAMALGSALRAVGDAKLSMVSTLIGGGVNAVFD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PIFIFMFAMGIEGAAVASVMARFAVFAVAAKGVVVKHNLLGRFNFDHFIEDLKPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCHHHHHHHHHHHHHHHC
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAILGRLIPVSFGMIFALSGAVGPIVGQNY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GALEFERVKESLTRAIQFCTAYVLGVSLLLFLTRHQIVSVFDMQGDAAELILFFCSYIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFIFSGILFVANASFNNLGKAKYSTLFNVGKATLGTIPFVYFGAQWGGVYGVLIGQAIGS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHH
IIFGILGVLVAYQLVDKVQTMTVAGLYGANIPKDEEKTEFDEELSLSSQSPMSSSCANMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
MVNEEQDCEASNEVAELIGVKEDNASTK
HCCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVAKFVQGSILRHILVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHH
FTTSIGIGLSIALGALVSRSIGAKETEIAKRLLLNSLVVTFLISVFVAFTIYMFIPELLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGATGKTAELAESYLNILVPSLPLICLAMALGSALRAVGDAKLSMVSTLIGGGVNAVFD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PIFIFMFAMGIEGAAVASVMARFAVFAVAAKGVVVKHNLLGRFNFDHFIEDLKPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCHHHHHHHHHHHHHHHC
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAILGRLIPVSFGMIFALSGAVGPIVGQNY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GALEFERVKESLTRAIQFCTAYVLGVSLLLFLTRHQIVSVFDMQGDAAELILFFCSYIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFIFSGILFVANASFNNLGKAKYSTLFNVGKATLGTIPFVYFGAQWGGVYGVLIGQAIGS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHH
IIFGILGVLVAYQLVDKVQTMTVAGLYGANIPKDEEKTEFDEELSLSSQSPMSSSCANMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
MVNEEQDCEASNEVAELIGVKEDNASTK
HCCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]