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The map label for this gene is rmlC [H]

Identifier: 167623434

GI number: 167623434

Start: 1809065

End: 1809634

Strand: Direct

Name: rmlC [H]

Synonym: Shal_1503

Alternate gene names: 167623434

Gene position: 1809065-1809634 (Clockwise)

Preceding gene: 167623433

Following gene: 167623447

Centisome position: 34.61

GC content: 43.68

Gene sequence:

>570_bases
ATGATGAAACTAATTCCTACCCTAATTCCTGATGTGCTGCTGTTTGAACCTAAAGTCTTTGGTGATGAACGTGGTTTCTT
TATGGAAACCTTTCGCCAATCGGAGTTTGAGGCGTTATTTGCCAAAGTCGGCATGGCTTGTCCGAGCTTTGTACAAGAGA
ATATGAGTCGATCGCAAAAACATGTGCTGCGTGGGCTGCATTATCAAGAGACTCATCCACAAGGTAAGCTTGTTCGCGTC
ACTGCAGGTAGCATTTTTGATGTTGCCGTCGATATTCGTAAAGCCTCAAAAACCTACGGCCAGTGGTTTGGTCAAGTGTT
ATCTGCCGAAAACAGACTGCAAATGTATATCCCTCCAGGTTTTGCCCACGGTTTTTTAACTTTAAGTGACCATGCTGACA
TTATCTATAAATGCACCGCTTACTATGCGGCAGAGTTTGAAAAGTGCATTACGTGGAATGATCCTCAATTAAATATTCAA
TGGCCGTTAGAAGAGGGCGTTGAACCTATTTTGTCGGAGAAGGATGGGAAAGCTGATAAGTTCCTAGGTCCGAGGAAAAG
CAGGTTCTAG

Upstream 100 bases:

>100_bases
TAGGTCCTAGAACCTTGTTTATTCAGTGAGCTTGCGAACGTCCTAGAACCTTGGACGCGCAGAGTTCGTCTAAGCTTTAT
TTGACCTTATTTAAAAGAAT

Downstream 100 bases:

>100_bases
GTAAAAGCCAAGACGGTACAAGCTGAGACGGCAAAGCGGAGCGGTCTATGACCTTACGGATTACGGAACGTTCGCAGGCT
CACTTACGGAACGCTTCGCT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMKLIPTLIPDVLLFEPKVFGDERGFFMETFRQSEFEALFAKVGMACPSFVQENMSRSQKHVLRGLHYQETHPQGKLVRV
TAGSIFDVAVDIRKASKTYGQWFGQVLSAENRLQMYIPPGFAHGFLTLSDHADIIYKCTAYYAAEFEKCITWNDPQLNIQ
WPLEEGVEPILSEKDGKADKFLGPRKSRF

Sequences:

>Translated_189_residues
MMKLIPTLIPDVLLFEPKVFGDERGFFMETFRQSEFEALFAKVGMACPSFVQENMSRSQKHVLRGLHYQETHPQGKLVRV
TAGSIFDVAVDIRKASKTYGQWFGQVLSAENRLQMYIPPGFAHGFLTLSDHADIIYKCTAYYAAEFEKCITWNDPQLNIQ
WPLEEGVEPILSEKDGKADKFLGPRKSRF
>Mature_189_residues
MMKLIPTLIPDVLLFEPKVFGDERGFFMETFRQSEFEALFAKVGMACPSFVQENMSRSQKHVLRGLHYQETHPQGKLVRV
TAGSIFDVAVDIRKASKTYGQWFGQVLSAENRLQMYIPPGFAHGFLTLSDHADIIYKCTAYYAAEFEKCITWNDPQLNIQ
WPLEEGVEPILSEKDGKADKFLGPRKSRF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=53.9325842696629, Blast_Score=181, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17550412, Length=182, Percent_Identity=44.5054945054945, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21645; Mature: 21645

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLIPTLIPDVLLFEPKVFGDERGFFMETFRQSEFEALFAKVGMACPSFVQENMSRSQK
CCCHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HVLRGLHYQETHPQGKLVRVTAGSIFDVAVDIRKASKTYGQWFGQVLSAENRLQMYIPPG
HHHHCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
FAHGFLTLSDHADIIYKCTAYYAAEFEKCITWNDPQLNIQWPLEEGVEPILSEKDGKADK
CCCCEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCHHHHCCCCCCCHH
FLGPRKSRF
CCCCCCCCC
>Mature Secondary Structure
MMKLIPTLIPDVLLFEPKVFGDERGFFMETFRQSEFEALFAKVGMACPSFVQENMSRSQK
CCCHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HVLRGLHYQETHPQGKLVRVTAGSIFDVAVDIRKASKTYGQWFGQVLSAENRLQMYIPPG
HHHHCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
FAHGFLTLSDHADIIYKCTAYYAAEFEKCITWNDPQLNIQWPLEEGVEPILSEKDGKADK
CCCCEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCHHHHCCCCCCCHH
FLGPRKSRF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]