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The map label for this gene is mlaA [H]

Identifier: 167623408

GI number: 167623408

Start: 1775519

End: 1776289

Strand: Direct

Name: mlaA [H]

Synonym: Shal_1477

Alternate gene names: 167623408

Gene position: 1775519-1776289 (Clockwise)

Preceding gene: 167623405

Following gene: 167623409

Centisome position: 33.97

GC content: 42.41

Gene sequence:

>771_bases
ATGAAGTTTAAATGGATTGTGTTTTCTCTGGCGATATTTGGAATGCCTTCAATTGAAGCTGCAGAAGACAGCACTACGGA
TGATGCTAAACAGATCACAGTAACCTATAACGACCCAAGGGATCCTATAGAGGGTTTTAACCGCGTCATGTGGGATTTTA
ACTATCTGTTTATGGATAGGTATTTTTATCGCCCAGTTGCCCATGGCTATCATGATTACATCCCGCATCCGGTGAAAAGC
GGGATTAATAATTTTGTGTTAAACCTTGAAGAGCCATCTAGCCTAGTTAACAACACCCTGCAAGGCAAATGGGGTTGGGC
CGCCAATGCGGGCGGACGCTTCACCGTTAATTCAACGCTAGGCCTATTAGGTGTCATTGATGTCGCCGAAATGATGGGCA
TGACACGTAAACAAGACGATTTTAGTGAAGTGCTAGGTTATTACGGTGTACCAAATGGTCCCTATTTTATGGCACCGTTT
ATTGGTCCCTATGTCACTCGTGAAATCGCATCAGACTGGGTTGATGAACTATACTTTCCTCTATCTGAGTTGACGTTTTG
GCAATCAGCACTAAAATGGGGTCTTAAAAGTTTGCATACTCGAGCGGCTGCAATCGATCAGGAACGATTGGTTGATAACG
CTCTTGACCCATATACCTTCGTTAAAGATGCTTATTTTCAACATATAGATTACCAGGTATATGACGGTGATATTCCTCAA
AGTGACGATAATGATGAGTTGCTTGATGAGTATATGCAGGAATTAGAATAG

Upstream 100 bases:

>100_bases
AACCCTATACGACTTTAGCTGGAATGTAGAATTTAGTCAGTGAGCCAAAATGTACTAAGGTAAAGACGAGTGCTACTGAC
TCCTTTTCAAAGAGACAATT

Downstream 100 bases:

>100_bases
CATTCGATAAGTGGACAGATAAAAATAAAAGCTCCGCTTAAAGCGCAAACATAAACATGGACGTGTGTTTTCGCTGTTGT
CAGTAAAGGGCAGCTTATGG

Product: VacJ family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKFKWIVFSLAIFGMPSIEAAEDSTTDDAKQITVTYNDPRDPIEGFNRVMWDFNYLFMDRYFYRPVAHGYHDYIPHPVKS
GINNFVLNLEEPSSLVNNTLQGKWGWAANAGGRFTVNSTLGLLGVIDVAEMMGMTRKQDDFSEVLGYYGVPNGPYFMAPF
IGPYVTREIASDWVDELYFPLSELTFWQSALKWGLKSLHTRAAAIDQERLVDNALDPYTFVKDAYFQHIDYQVYDGDIPQ
SDDNDELLDEYMQELE

Sequences:

>Translated_256_residues
MKFKWIVFSLAIFGMPSIEAAEDSTTDDAKQITVTYNDPRDPIEGFNRVMWDFNYLFMDRYFYRPVAHGYHDYIPHPVKS
GINNFVLNLEEPSSLVNNTLQGKWGWAANAGGRFTVNSTLGLLGVIDVAEMMGMTRKQDDFSEVLGYYGVPNGPYFMAPF
IGPYVTREIASDWVDELYFPLSELTFWQSALKWGLKSLHTRAAAIDQERLVDNALDPYTFVKDAYFQHIDYQVYDGDIPQ
SDDNDELLDEYMQELE
>Mature_256_residues
MKFKWIVFSLAIFGMPSIEAAEDSTTDDAKQITVTYNDPRDPIEGFNRVMWDFNYLFMDRYFYRPVAHGYHDYIPHPVKS
GINNFVLNLEEPSSLVNNTLQGKWGWAANAGGRFTVNSTLGLLGVIDVAEMMGMTRKQDDFSEVLGYYGVPNGPYFMAPF
IGPYVTREIASDWVDELYFPLSELTFWQSALKWGLKSLHTRAAAIDQERLVDNALDPYTFVKDAYFQHIDYQVYDGDIPQ
SDDNDELLDEYMQELE

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=220, Percent_Identity=39.0909090909091, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 29464; Mature: 29464

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKWIVFSLAIFGMPSIEAAEDSTTDDAKQITVTYNDPRDPIEGFNRVMWDFNYLFMDR
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YFYRPVAHGYHDYIPHPVKSGINNFVLNLEEPSSLVNNTLQGKWGWAANAGGRFTVNSTL
HHHHHHHCCHHHCCCCHHHCCHHHEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCHH
GLLGVIDVAEMMGMTRKQDDFSEVLGYYGVPNGPYFMAPFIGPYVTREIASDWVDELYFP
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
LSELTFWQSALKWGLKSLHTRAAAIDQERLVDNALDPYTFVKDAYFQHIDYQVYDGDIPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCC
SDDNDELLDEYMQELE
CCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKFKWIVFSLAIFGMPSIEAAEDSTTDDAKQITVTYNDPRDPIEGFNRVMWDFNYLFMDR
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YFYRPVAHGYHDYIPHPVKSGINNFVLNLEEPSSLVNNTLQGKWGWAANAGGRFTVNSTL
HHHHHHHCCHHHCCCCHHHCCHHHEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCHH
GLLGVIDVAEMMGMTRKQDDFSEVLGYYGVPNGPYFMAPFIGPYVTREIASDWVDELYFP
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
LSELTFWQSALKWGLKSLHTRAAAIDQERLVDNALDPYTFVKDAYFQHIDYQVYDGDIPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCC
SDDNDELLDEYMQELE
CCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]