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The map label for this gene is dsbA [H]

Identifier: 167622431

GI number: 167622431

Start: 591473

End: 592141

Strand: Direct

Name: dsbA [H]

Synonym: Shal_0491

Alternate gene names: 167622431

Gene position: 591473-592141 (Clockwise)

Preceding gene: 167622430

Following gene: 167622432

Centisome position: 11.32

GC content: 47.09

Gene sequence:

>669_bases
ATGAAAAAACGCTTAGTTAGTCTGTTTCTCACCTTCGCTATGATAGCTTGTTCCGAGCCGTCTAAACTGGACGTCGACGG
CAACCTTGTTGAAGGTTTTGTCGAAGGCGTGCATTACCGCACTTTAGCAACACCGATCCCTGCTAGTAATGATGATATTT
CGGTAACCGAGTTTTTCTGGTACGGCTGTCCCCATTGTCAGCTTTTTGAAAAACCACTACACGATTGGGAGAAAACCATG
GCTGATGGCGTCACCTTAGTGCAGTCGCCAGCGGTGTGGAGTGAGGCCATGAAGCTACATGCCAAAGTGTTTTTCATTGT
GCAGCAGATGGAAAATATGCAGCAGGTGCACGCCGCGCTTTTTGAAGAAATAGTTGGCCTTCGGGAAGTGAGAGACCTAA
ATGAACAGCAAGCAAAGCTTGGCGTATTCTTAAGTGGTTATGGCTTAACGCAGCAGAAGTTTAACGAGAAACTCAATTCG
GCAGATATCATCTCTAAGCTTAAGCAAGCGATACAGCTGATGTCATCGGCTGAGATCAATGGCACGCCAACCATCTTAGT
CAATGGCCGCTATATCGTGCTGAATGACTCGGCTAGTTCGGCCAAGCAGGTGATGGATATCGCCAGCTATTTAGTTGAAC
TGGAAAAAGCTAGGCTCGCCAATCCCTAA

Upstream 100 bases:

>100_bases
TGCCTTTTTGTTTTTGGGCTAATATGTGATGAGTGCTGGTGATGAGTCTAACTGGCAATAGCCAGCTATATAGTCAATCA
CGCGAACAAAAGGACCTGTC

Downstream 100 bases:

>100_bases
TACTAACCAAACTCTTGGCTCATAAATTAAGCCATTCTGGTTGAAAAATCACCACCAACCAAGTTGGAAAATTCAGAAAT
AGCATGGTTAGTTGAACAGC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKKRLVSLFLTFAMIACSEPSKLDVDGNLVEGFVEGVHYRTLATPIPASNDDISVTEFFWYGCPHCQLFEKPLHDWEKTM
ADGVTLVQSPAVWSEAMKLHAKVFFIVQQMENMQQVHAALFEEIVGLREVRDLNEQQAKLGVFLSGYGLTQQKFNEKLNS
ADIISKLKQAIQLMSSAEINGTPTILVNGRYIVLNDSASSAKQVMDIASYLVELEKARLANP

Sequences:

>Translated_222_residues
MKKRLVSLFLTFAMIACSEPSKLDVDGNLVEGFVEGVHYRTLATPIPASNDDISVTEFFWYGCPHCQLFEKPLHDWEKTM
ADGVTLVQSPAVWSEAMKLHAKVFFIVQQMENMQQVHAALFEEIVGLREVRDLNEQQAKLGVFLSGYGLTQQKFNEKLNS
ADIISKLKQAIQLMSSAEINGTPTILVNGRYIVLNDSASSAKQVMDIASYLVELEKARLANP
>Mature_222_residues
MKKRLVSLFLTFAMIACSEPSKLDVDGNLVEGFVEGVHYRTLATPIPASNDDISVTEFFWYGCPHCQLFEKPLHDWEKTM
ADGVTLVQSPAVWSEAMKLHAKVFFIVQQMENMQQVHAALFEEIVGLREVRDLNEQQAKLGVFLSGYGLTQQKFNEKLNS
ADIISKLKQAIQLMSSAEINGTPTILVNGRYIVLNDSASSAKQVMDIASYLVELEKARLANP

Specific function: Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1348 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023205
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: 5.3.4.1

Molecular weight: Translated: 24827; Mature: 24827

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLVSLFLTFAMIACSEPSKLDVDGNLVEGFVEGVHYRTLATPIPASNDDISVTEFFW
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YGCPHCQLFEKPLHDWEKTMADGVTLVQSPAVWSEAMKLHAKVFFIVQQMENMQQVHAAL
CCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEIVGLREVRDLNEQQAKLGVFLSGYGLTQQKFNEKLNSADIISKLKQAIQLMSSAEIN
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
GTPTILVNGRYIVLNDSASSAKQVMDIASYLVELEKARLANP
CCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKRLVSLFLTFAMIACSEPSKLDVDGNLVEGFVEGVHYRTLATPIPASNDDISVTEFFW
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YGCPHCQLFEKPLHDWEKTMADGVTLVQSPAVWSEAMKLHAKVFFIVQQMENMQQVHAAL
CCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEIVGLREVRDLNEQQAKLGVFLSGYGLTQQKFNEKLNSADIISKLKQAIQLMSSAEIN
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
GTPTILVNGRYIVLNDSASSAKQVMDIASYLVELEKARLANP
CCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10051655 [H]