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The map label for this gene is nahR [H]

Identifier: 167622263

GI number: 167622263

Start: 382088

End: 383020

Strand: Direct

Name: nahR [H]

Synonym: Shal_0322

Alternate gene names: 167622263

Gene position: 382088-383020 (Clockwise)

Preceding gene: 167622261

Following gene: 167622264

Centisome position: 7.31

GC content: 50.27

Gene sequence:

>933_bases
ATGGATCTCGCAAAACTCTCTCGGATCAGCATGAAGCATCTGATCACTCTGCATGTGATGCTCGACACCCTGAGCGTCAC
CGCCAGTGCCGAGCGTTTATGTTTGAGTCCATCATCGGTCAGTAAGACCTTGAGTCAACTTAGGCTCAGTCTGGACGATG
AGCTGTTCTACCGCCACGGCAATAAGCTGGTGGCCACACCGCTAGCCCGCAGACTAGGCCCAAGCGTGCATCAAATAATC
AATGATATGAATCAGTTGATGACCAAGGAGGCGTTTAACCCTGCAGACTATGAGGGGCGTTTCTCATTGGCGATGCGCGA
GAGTACCTTTGAGCTGTTAGCGGTAAAATTTATGGCTCACGTACTGACGCTCGCGCCCAATATTCGTTTAGATATTTTCG
CTAAAGACAGTGTGGGTTTTGAGGGGCTAGTCAAAGGCAGTTTGGATTTTATCCTGCTGCCCCATGATAGAAGTCAGCCA
CCGATCTCCCTGCATGAACTGGTATGGGAAACCTTAATTAATGACGAGATGGTGTGTCTGATGAAGCCTGCGCATCCATT
GGCGACTCAGGCGCAGATCTCTATCGAGGATTACCTGAGTTTCAGCCACATAGGTATTAGCGATGCAGACCTCAATACGC
CCTTTTTTGAGATGCAGTTAGCCCAGCGGGCACGCAATCGCGCTGTGCCGATTTCAGTGGCCGACTTTGGTAGTGCGGCG
TTACTGTGCTATCACAGTGATCTGCTGTTTACTTGTTCGCGGCGTTGGGCTGAAACGGCGCTTCAGGCCCAAGGTTTGGT
GACTAAGGCATTGCCCTTAGACTATGGCGAGGTGGCCTATAGTTTGGTGTGGCATAAGCAGAGTATGAATGACCCCGCTT
TGCGGTGGTTGTATCAACAGTTGGTTGAGTTTACCCAAATGGAGTTTCAATAA

Upstream 100 bases:

>100_bases
GTGAATATAGGGTTTAGCAATATACCGCACCGATATTTACGTCTATATTCCAGTTTATGAATCTAGTTTATAAATAAAAC
GCTCTCTAAAAGGCAAACTG

Downstream 100 bases:

>100_bases
ACTTCACCAAAAGTTTATTGGTTCATTGGGTTTGAGGGCGAATCAAACTTCGTTTGATAAACGTGGTTTTACCACATTGG
TAATGCATCAGGCTTCGCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLSLDDELFYRHGNKLVATPLARRLGPSVHQII
NDMNQLMTKEAFNPADYEGRFSLAMRESTFELLAVKFMAHVLTLAPNIRLDIFAKDSVGFEGLVKGSLDFILLPHDRSQP
PISLHELVWETLINDEMVCLMKPAHPLATQAQISIEDYLSFSHIGISDADLNTPFFEMQLAQRARNRAVPISVADFGSAA
LLCYHSDLLFTCSRRWAETALQAQGLVTKALPLDYGEVAYSLVWHKQSMNDPALRWLYQQLVEFTQMEFQ

Sequences:

>Translated_310_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLSLDDELFYRHGNKLVATPLARRLGPSVHQII
NDMNQLMTKEAFNPADYEGRFSLAMRESTFELLAVKFMAHVLTLAPNIRLDIFAKDSVGFEGLVKGSLDFILLPHDRSQP
PISLHELVWETLINDEMVCLMKPAHPLATQAQISIEDYLSFSHIGISDADLNTPFFEMQLAQRARNRAVPISVADFGSAA
LLCYHSDLLFTCSRRWAETALQAQGLVTKALPLDYGEVAYSLVWHKQSMNDPALRWLYQQLVEFTQMEFQ
>Mature_310_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLSLDDELFYRHGNKLVATPLARRLGPSVHQII
NDMNQLMTKEAFNPADYEGRFSLAMRESTFELLAVKFMAHVLTLAPNIRLDIFAKDSVGFEGLVKGSLDFILLPHDRSQP
PISLHELVWETLINDEMVCLMKPAHPLATQAQISIEDYLSFSHIGISDADLNTPFFEMQLAQRARNRAVPISVADFGSAA
LLCYHSDLLFTCSRRWAETALQAQGLVTKALPLDYGEVAYSLVWHKQSMNDPALRWLYQQLVEFTQMEFQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=290, Percent_Identity=24.1379310344828, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34980; Mature: 34980

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50931 HTH_LYSR ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLSLDDELFYRHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCC
NKLVATPLARRLGPSVHQIINDMNQLMTKEAFNPADYEGRFSLAMRESTFELLAVKFMAH
CEEEECHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
VLTLAPNIRLDIFAKDSVGFEGLVKGSLDFILLPHDRSQPPISLHELVWETLINDEMVCL
HHHHCCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEE
MKPAHPLATQAQISIEDYLSFSHIGISDADLNTPFFEMQLAQRARNRAVPISVADFGSAA
ECCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
LLCYHSDLLFTCSRRWAETALQAQGLVTKALPLDYGEVAYSLVWHKQSMNDPALRWLYQQ
EEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LVEFTQMEFQ
HHHHHHHCCC
>Mature Secondary Structure
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLSLDDELFYRHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCC
NKLVATPLARRLGPSVHQIINDMNQLMTKEAFNPADYEGRFSLAMRESTFELLAVKFMAH
CEEEECHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
VLTLAPNIRLDIFAKDSVGFEGLVKGSLDFILLPHDRSQPPISLHELVWETLINDEMVCL
HHHHCCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEE
MKPAHPLATQAQISIEDYLSFSHIGISDADLNTPFFEMQLAQRARNRAVPISVADFGSAA
ECCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
LLCYHSDLLFTCSRRWAETALQAQGLVTKALPLDYGEVAYSLVWHKQSMNDPALRWLYQQ
EEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LVEFTQMEFQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]