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The map label for this gene is pqqL [C]

Identifier: 167622260

GI number: 167622260

Start: 378480

End: 379811

Strand: Direct

Name: pqqL [C]

Synonym: Shal_0319

Alternate gene names: 167622260

Gene position: 378480-379811 (Clockwise)

Preceding gene: 167622258

Following gene: 167622261

Centisome position: 7.24

GC content: 49.47

Gene sequence:

>1332_bases
ATGAAGCGCTACACTAAGGCATTGTTATTGTCTATTGGTATGCTATTAGCAGCACCAATGGTACAAGCAACACAGGCCAA
AGATGTTCAAAGTTTCACTTTGGACAACGGCATGAAGATCATGGTACTGGAAGATAGTTCAATACCAAACGCCAATATGT
ACCTTTTTTGGAAGGTGGGTTCACGCAATGAGGTACCGGGGATCACTGGGATCTCGCACTTCTTCGAGCATATGATGTTT
AACGGCTCTAAAAAATATGGGCCTAAGATGTTCGACCGCACTATGGAAGCGGCGGGCGGGGCGAACAACGCCTACACCAC
TGAGAACCTTACCGTATACACAGACTGGTTCCCCGCTAATGCGCTAGAGACCATTTTTGACTTGGAAGCTGACCGTATCG
AGAGTCTCGATATTAACGAGCAGATGGTTGAGAGTGAGCGCGGTGTGGTGGCATCGGAGCGTCTAACTGGACTTGAAAAC
TCTAACTGGCGCGTGTTGCAGGAGGAGCTAAAAGGCGCGGCCTTTAGAGCACACCCTTATAGCTGGTCGGTTATCGGCCA
TGAGTCGGATATTGCCGCTTGGACCCTTGAGGACCTGACTCAATATCACAAAACCTATTACGCACCGAATAACGCGGTCG
TGGTCATTGCCGGCGATGTGAAACTGGCTGAAGTGAAAAAGTTAGCCGATAAATACTTTGCACCAATCCCTGCACAAACG
CCACCAAGAGAGGTAAAAACCGTAGAGCCGCTACAAAAAGGTGAGCGCCGCGTCTTCGTTCAGAAACCCTCGGTAAGTAC
CCCCAATGTGATGCTAGGTTACCACATTCCGGCGACCTCAAATGCCGACTACTATGCACTGGATCTGCTGTCATCTATCT
TGGCCACGGGTAACAGCTCTCGCATGTATCAAGGCTTAGTCGACAAGCAGGTGGCCATCGAAGTTGATACCTATATGCCG
ATGTCATTTGATCCTAACCTATTCTACGTGATGGGCGTGGCCAATCCTGGTGTGACGGCTCCCGAGTTGGAAGATGCGAT
GATCAGCGAAATTAACCGCGTTGCCCGTGACGGTGTCACGGCCGAAGAGCTTGAAAAGGTAAAAAATATCAAGCTAATGG
GCTTTTATCGCGCCATGGAAACGATCAATGGCAAGGCTAATACCATAGGCACCTATGAGCTGTTTTTCGGTAGTTACGAC
AAGCTGTTTAATGCCCCAGAAGCCTACAACAAGGTGACGCCTGAAGATATTCAGCGTGTTGCGCAAACTTACCTGAAACG
TGCAAACCGTACCGTTGCCGTACTGGCTGCAACCGAGGAGGCTGACCAATGA

Upstream 100 bases:

>100_bases
AAATATCACCAGTTTGCAACCACAAGCGGGATATACAATTCGCCATGCTCTGACTGGAATAGATTAGAGATGGCAAGGGT
GCTTAAACAAGGAGCGAATA

Downstream 100 bases:

>100_bases
AAAAGTGTAATTCAACCCTAATCGCCTCGACTACTTTGCTGCAATCTAAGAGGCTACTCACGGCGATGGCCGTTGCGGGT
ACGCTGGCCTTATCTGGTTG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKRYTKALLLSIGMLLAAPMVQATQAKDVQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIESLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTQYHKTYYAPNNAVVVIAGDVKLAEVKKLADKYFAPIPAQT
PPREVKTVEPLQKGERRVFVQKPSVSTPNVMLGYHIPATSNADYYALDLLSSILATGNSSRMYQGLVDKQVAIEVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTAEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSYD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ

Sequences:

>Translated_443_residues
MKRYTKALLLSIGMLLAAPMVQATQAKDVQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIESLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTQYHKTYYAPNNAVVVIAGDVKLAEVKKLADKYFAPIPAQT
PPREVKTVEPLQKGERRVFVQKPSVSTPNVMLGYHIPATSNADYYALDLLSSILATGNSSRMYQGLVDKQVAIEVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTAEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSYD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ
>Mature_443_residues
MKRYTKALLLSIGMLLAAPMVQATQAKDVQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIESLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTQYHKTYYAPNNAVVVIAGDVKLAEVKKLADKYFAPIPAQT
PPREVKTVEPLQKGERRVFVQKPSVSTPNVMLGYHIPATSNADYYALDLLSSILATGNSSRMYQGLVDKQVAIEVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTAEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSYD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=306, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI155969707, Length=266, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI94538354, Length=418, Percent_Identity=23.6842105263158, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1787770, Length=385, Percent_Identity=22.8571428571429, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367164, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=224, Percent_Identity=28.125, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553678, Length=236, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146563, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25146566, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994338, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32566665, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115533970, Length=216, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=289, Percent_Identity=24.2214532871972, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323421, Length=197, Percent_Identity=26.3959390862944, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357875, Length=451, Percent_Identity=23.7250554323725, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24646943, Length=451, Percent_Identity=23.7250554323725, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI221513245, Length=218, Percent_Identity=24.3119266055046, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49456; Mature: 49456

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYTKALLLSIGMLLAAPMVQATQAKDVQSFTLDNGMKIMVLEDSSIPNANMYLFWKVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCEEEEEECCCCCCCCEEEEEEEC
SRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPAN
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCH
ALETIFDLEADRIESLDINEQMVESERGVVASERLTGLENSNWRVLQEELKGAAFRAHPY
HHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCC
SWSVIGHESDIAAWTLEDLTQYHKTYYAPNNAVVVIAGDVKLAEVKKLADKYFAPIPAQT
EEEEECCCCCCCEEEHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCC
PPREVKTVEPLQKGERRVFVQKPSVSTPNVMLGYHIPATSNADYYALDLLSSILATGNSS
CCCCCCHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
RMYQGLVDKQVAIEVDTYMPMSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVT
HHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
AEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSYDKLFNAPEAYNKVTPEDIQRV
HHHHHHHHCCEEEHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCHHHCCCCHHHHHHH
AQTYLKRANRTVAVLAATEEADQ
HHHHHHHCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKRYTKALLLSIGMLLAAPMVQATQAKDVQSFTLDNGMKIMVLEDSSIPNANMYLFWKVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCEEEEEECCCCCCCCEEEEEEEC
SRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPAN
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCH
ALETIFDLEADRIESLDINEQMVESERGVVASERLTGLENSNWRVLQEELKGAAFRAHPY
HHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCC
SWSVIGHESDIAAWTLEDLTQYHKTYYAPNNAVVVIAGDVKLAEVKKLADKYFAPIPAQT
EEEEECCCCCCCEEEHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCC
PPREVKTVEPLQKGERRVFVQKPSVSTPNVMLGYHIPATSNADYYALDLLSSILATGNSS
CCCCCCHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
RMYQGLVDKQVAIEVDTYMPMSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVT
HHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
AEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSYDKLFNAPEAYNKVTPEDIQRV
HHHHHHHHCCEEEHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCHHHCCCCHHHHHHH
AQTYLKRANRTVAVLAATEEADQ
HHHHHHHCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]