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The map label for this gene is perR [H]

Identifier: 167622169

GI number: 167622169

Start: 275174

End: 276064

Strand: Direct

Name: perR [H]

Synonym: Shal_0228

Alternate gene names: 167622169

Gene position: 275174-276064 (Clockwise)

Preceding gene: 167622168

Following gene: 167622174

Centisome position: 5.26

GC content: 43.21

Gene sequence:

>891_bases
ATGAATAATAACATCCCATTAAGGGCGTTACAGGTTTTTGAATCATGCGCAAGGCTGGAAAGCTGCTCGCTTGCTGCGAA
TGAGTTATGCATCACTCAGAGCGCGGTCTCTCAACAGATAAAGCTGCTTGAAGATTACTTCTTAGAAAAGCTATTTCACC
GCAATGCGGGCAAAATTACTCTGACTGAATCAGGGCTTGAACTTAGGCAAAGATTAGCGCCGGTTTTTTATGATTTAAAC
AGTGTGTGTGCCAGTTTGGTGCCCGATATGTCTAACGAAGTTCGAGTACATTCTTATAACTCTTTAGCCGCCCGTTGGTT
AGTACCTAAGATGGCTAAGCTGAGAAAAGAGCACCCTGAGTTCAACATCAATGTTGGTATGTTTCAAGATGATGTAGAGA
TGAGCGATATGATCGCCGATATCTTTATTATCACCCGCGAATGCCAAGACGGCTATACCATTACTCCGTTAGTCGAAGAG
AAGCTGGTGGCTTTTTGTAGCCCTGAATATTTGCAAAAACACCCAGAGATCTCCTTAAGTACTTTCCATGAGCAGACACT
ACTTTACTCAAAACACAAAGATTATGGTGTCGATTGGGAAGGCTGGTTTAGAGATAACAAAGTCGCTGTCGGCCCATTAC
AGCGAAAAATTATTTTCAACCATAATATGTTGGCAGTTCAGGCAGCAATTTTTGGTCAGGGGATCGTGCTAGGCCTAGAG
CAAACGCTACAAGTAGAATTAGACTCAGGAAACCTGGTGAAGTTAGATCTCCCCCATTGCTATACAGGCTGGACCTACTC
AATCGCTTATAAGTCTTCAAGAAAGCGGGACGCCCGTATAACCAAGATTGTCGATTGGATAATTAAAGAATATGCGGGCA
GCGTATCTTAG

Upstream 100 bases:

>100_bases
GAAAAATTAATTCGCATCTTATTGTGCTCACAGTTACATTTTTACTCTAAAACCTTGTGCTAGTCTCGTGCATCATGCAC
TTAAACTATGTATATAAAAT

Downstream 100 bases:

>100_bases
CCGCAATTGTTATTTATCTGATTAAAGCTGTATCAGTACTAATCGAGAAGCTGAGGGAGAAGGTTTACTCGTGATTGGGG
AAACTGTGGAAGAGAGTTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Peroxide resistance protein perR [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNNNIPLRALQVFESCARLESCSLAANELCITQSAVSQQIKLLEDYFLEKLFHRNAGKITLTESGLELRQRLAPVFYDLN
SVCASLVPDMSNEVRVHSYNSLAARWLVPKMAKLRKEHPEFNINVGMFQDDVEMSDMIADIFIITRECQDGYTITPLVEE
KLVAFCSPEYLQKHPEISLSTFHEQTLLYSKHKDYGVDWEGWFRDNKVAVGPLQRKIIFNHNMLAVQAAIFGQGIVLGLE
QTLQVELDSGNLVKLDLPHCYTGWTYSIAYKSSRKRDARITKIVDWIIKEYAGSVS

Sequences:

>Translated_296_residues
MNNNIPLRALQVFESCARLESCSLAANELCITQSAVSQQIKLLEDYFLEKLFHRNAGKITLTESGLELRQRLAPVFYDLN
SVCASLVPDMSNEVRVHSYNSLAARWLVPKMAKLRKEHPEFNINVGMFQDDVEMSDMIADIFIITRECQDGYTITPLVEE
KLVAFCSPEYLQKHPEISLSTFHEQTLLYSKHKDYGVDWEGWFRDNKVAVGPLQRKIIFNHNMLAVQAAIFGQGIVLGLE
QTLQVELDSGNLVKLDLPHCYTGWTYSIAYKSSRKRDARITKIVDWIIKEYAGSVS
>Mature_296_residues
MNNNIPLRALQVFESCARLESCSLAANELCITQSAVSQQIKLLEDYFLEKLFHRNAGKITLTESGLELRQRLAPVFYDLN
SVCASLVPDMSNEVRVHSYNSLAARWLVPKMAKLRKEHPEFNINVGMFQDDVEMSDMIADIFIITRECQDGYTITPLVEE
KLVAFCSPEYLQKHPEISLSTFHEQTLLYSKHKDYGVDWEGWFRDNKVAVGPLQRKIIFNHNMLAVQAAIFGQGIVLGLE
QTLQVELDSGNLVKLDLPHCYTGWTYSIAYKSSRKRDARITKIVDWIIKEYAGSVS

Specific function: Apparent regulatory gene involved in peroxide resistance in stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786448, Length=251, Percent_Identity=31.0756972111554, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=32.1428571428571, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788706, Length=258, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=26.4214046822742, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=22.5165562913907, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787128, Length=258, Percent_Identity=25.968992248062, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33785; Mature: 33785

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNIPLRALQVFESCARLESCSLAANELCITQSAVSQQIKLLEDYFLEKLFHRNAGKIT
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LTESGLELRQRLAPVFYDLNSVCASLVPDMSNEVRVHSYNSLAARWLVPKMAKLRKEHPE
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCC
FNINVGMFQDDVEMSDMIADIFIITRECQDGYTITPLVEEKLVAFCSPEYLQKHPEISLS
EEEEEECEECCCHHHHHHHHHHHEEEECCCCCEECHHHHHHHHHHCCHHHHHHCCCCCHH
TFHEQTLLYSKHKDYGVDWEGWFRDNKVAVGPLQRKIIFNHNMLAVQAAIFGQGIVLGLE
HHHHHHHHHHCCCCCCCCCCCEECCCCEEECCHHEEEEECCCHHHHHHHHHCCCEEEEEC
QTLQVELDSGNLVKLDLPHCYTGWTYSIAYKSSRKRDARITKIVDWIIKEYAGSVS
EEEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNNIPLRALQVFESCARLESCSLAANELCITQSAVSQQIKLLEDYFLEKLFHRNAGKIT
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LTESGLELRQRLAPVFYDLNSVCASLVPDMSNEVRVHSYNSLAARWLVPKMAKLRKEHPE
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCC
FNINVGMFQDDVEMSDMIADIFIITRECQDGYTITPLVEEKLVAFCSPEYLQKHPEISLS
EEEEEECEECCCHHHHHHHHHHHEEEECCCCCEECHHHHHHHHHHCCHHHHHHCCCCCHH
TFHEQTLLYSKHKDYGVDWEGWFRDNKVAVGPLQRKIIFNHNMLAVQAAIFGQGIVLGLE
HHHHHHHHHHCCCCCCCCCCCEECCCCEEECCHHEEEEECCCHHHHHHHHHCCCEEEEEC
QTLQVELDSGNLVKLDLPHCYTGWTYSIAYKSSRKRDARITKIVDWIIKEYAGSVS
EEEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]