Click here to switch to the map view.

The map label for this gene is vmrA [H]

Identifier: 167622147

GI number: 167622147

Start: 247116

End: 248498

Strand: Reverse

Name: vmrA [H]

Synonym: Shal_0206

Alternate gene names: 167622147

Gene position: 248498-247116 (Counterclockwise)

Preceding gene: 167622150

Following gene: 167622143

Centisome position: 4.75

GC content: 48.01

Gene sequence:

>1383_bases
ATGTTAGCCCAAAGTATCGAAAACAACTCAAACGACTCCATTAGCCGTACCTTTTGGCGTTACACCCTGCCAGCAATTGC
TGCAATGCTGGTTAACGGCCTATATCAAATTGTCGATGGCATCTTTATCGGCCATTACATCGGTTATGAAGGCTTAGCCG
CCATCAACATGGCCTGGCCGGTTATCTACTTTATGGTGGGTTTTGGCATCATGATCGGTATGGGCAGTGGTAGCTTGTTG
TCGATTCAACGTGGCAAGGGCGATACTAGCGCTGCCCCGACAATTTTGACCACCAGCTTGCTGAGCATGTTGGCACTAGC
AGTCGCCTCCAGTGCAATATTATCAATCTTAAGCACCTTCTTCCTTGAGGCTCAAGGCGGCGCAGGCACAACCTTAGTCA
TGGCCCAAGACTATATTAGCGTCTTCAGCTGGGGCACCGCTATCACCATCATAGCCTCGGCACTGCCACTACTGATCCGC
AATGATGAGAGCCCCAATATCGCAACAGGTCTAATGGTATTGGGCGCCTTTATTAATATTGCACTCGATTATCTATTGAT
CGGTGTCTTCGAGTTTGGCTTACTTGGCGCCGCGATTGCGACAATTACCGCCCAGCTAACGGTTTGTATACTCGGGCTGG
TGTACTTTTGCTCGCGCATTAGCAATATCAGCTGGCCAAGTAAATTTCGCTATTTCAATGCGTCCTTTGCCAAGCAGATC
GTACTCTTAGGTTCATCGAGCCTATTTATGTACCTGTATACCAGCTTCGTTTTTGCCCTGCATAATCGACTCTTTATCGA
ATATGGCACACCGTTAACTGTAGGGGCATTTGCGATTGTTGGCTACCTTATGGTGCTGTATTACTTGGTCTCCGAGGGAA
TTGCTGAGGGTCTGCAGCCTCCGGTGAGTTATTACTATGGCGCCGAGCAACACGCCAACATAAATAAGATGCTTAAGCTT
TCTATCAAGGTGACACTCATTGCGGGTACGAGCTGGATTCTATTACTCAATGCGATCCCTGAGACTATGGTAAAGCTGTT
CAACAGCAGTGATAGTGAGTTGATTGCAACGGCTGTCGATGGCATACGCATGCATCTATTTGCCATGCCTCTAGACGGTT
TTATTGTTCTGTCTTCAGTGTACTTTATGGCGACTAATCAAGGCGTCAAAGCACTGGTTATCGCTTGCGGCAATATGCTT
ATTCAGCTGCCATTCTTGATGATTCTACCTAAGTTTTTCGGCGTCGACGGAGTGTGGATGGCGATGCCAATCTCCAACAT
CGCTCTGTGTCTAATTGTGGTGCCTTTAGTTTGGTTAGATGTCAAAGCGCGGGCTCGCAAATTCGGGCCGACAACAACTG
AGGCTGTGATAGCAACCGCCTGA

Upstream 100 bases:

>100_bases
AACCTGCCCAACCTATATCTAAAACAGATAGAAGCTAACTTTATTCAATCTGAATAACAGAGTAACTTGCCGCTCATTAT
TCTCCAAATTTTGTACCTAA

Downstream 100 bases:

>100_bases
ACCCGGCACTAGGTTCTACGATAGCGCTTTAGCAATATCTGCACTCGCTCAACATAGGCTTGGGTCTCGGGGTAAGGTGG
CACCCCATTATACTGCTCTA

Product: multidrug efflux pump VmrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLAQSIENNSNDSISRTFWRYTLPAIAAMLVNGLYQIVDGIFIGHYIGYEGLAAINMAWPVIYFMVGFGIMIGMGSGSLL
SIQRGKGDTSAAPTILTTSLLSMLALAVASSAILSILSTFFLEAQGGAGTTLVMAQDYISVFSWGTAITIIASALPLLIR
NDESPNIATGLMVLGAFINIALDYLLIGVFEFGLLGAAIATITAQLTVCILGLVYFCSRISNISWPSKFRYFNASFAKQI
VLLGSSSLFMYLYTSFVFALHNRLFIEYGTPLTVGAFAIVGYLMVLYYLVSEGIAEGLQPPVSYYYGAEQHANINKMLKL
SIKVTLIAGTSWILLLNAIPETMVKLFNSSDSELIATAVDGIRMHLFAMPLDGFIVLSSVYFMATNQGVKALVIACGNML
IQLPFLMILPKFFGVDGVWMAMPISNIALCLIVVPLVWLDVKARARKFGPTTTEAVIATA

Sequences:

>Translated_460_residues
MLAQSIENNSNDSISRTFWRYTLPAIAAMLVNGLYQIVDGIFIGHYIGYEGLAAINMAWPVIYFMVGFGIMIGMGSGSLL
SIQRGKGDTSAAPTILTTSLLSMLALAVASSAILSILSTFFLEAQGGAGTTLVMAQDYISVFSWGTAITIIASALPLLIR
NDESPNIATGLMVLGAFINIALDYLLIGVFEFGLLGAAIATITAQLTVCILGLVYFCSRISNISWPSKFRYFNASFAKQI
VLLGSSSLFMYLYTSFVFALHNRLFIEYGTPLTVGAFAIVGYLMVLYYLVSEGIAEGLQPPVSYYYGAEQHANINKMLKL
SIKVTLIAGTSWILLLNAIPETMVKLFNSSDSELIATAVDGIRMHLFAMPLDGFIVLSSVYFMATNQGVKALVIACGNML
IQLPFLMILPKFFGVDGVWMAMPISNIALCLIVVPLVWLDVKARARKFGPTTTEAVIATA
>Mature_460_residues
MLAQSIENNSNDSISRTFWRYTLPAIAAMLVNGLYQIVDGIFIGHYIGYEGLAAINMAWPVIYFMVGFGIMIGMGSGSLL
SIQRGKGDTSAAPTILTTSLLSMLALAVASSAILSILSTFFLEAQGGAGTTLVMAQDYISVFSWGTAITIIASALPLLIR
NDESPNIATGLMVLGAFINIALDYLLIGVFEFGLLGAAIATITAQLTVCILGLVYFCSRISNISWPSKFRYFNASFAKQI
VLLGSSSLFMYLYTSFVFALHNRLFIEYGTPLTVGAFAIVGYLMVLYYLVSEGIAEGLQPPVSYYYGAEQHANINKMLKL
SIKVTLIAGTSWILLLNAIPETMVKLFNSSDSELIATAVDGIRMHLFAMPLDGFIVLSSVYFMATNQGVKALVIACGNML
IQLPFLMILPKFFGVDGVWMAMPISNIALCLIVVPLVWLDVKARARKFGPTTTEAVIATA

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49725; Mature: 49725

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQSIENNSNDSISRTFWRYTLPAIAAMLVNGLYQIVDGIFIGHYIGYEGLAAINMAWP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VIYFMVGFGIMIGMGSGSLLSIQRGKGDTSAAPTILTTSLLSMLALAVASSAILSILSTF
HHHHHHHHHHHEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLEAQGGAGTTLVMAQDYISVFSWGTAITIIASALPLLIRNDESPNIATGLMVLGAFINI
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHH
ALDYLLIGVFEFGLLGAAIATITAQLTVCILGLVYFCSRISNISWPSKFRYFNASFAKQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEECHHHHHHH
VLLGSSSLFMYLYTSFVFALHNRLFIEYGTPLTVGAFAIVGYLMVLYYLVSEGIAEGLQP
HEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVSYYYGAEQHANINKMLKLSIKVTLIAGTSWILLLNAIPETMVKLFNSSDSELIATAVD
CHHHHCCCCCCCCHHHEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GIRMHLFAMPLDGFIVLSSVYFMATNQGVKALVIACGNMLIQLPFLMILPKFFGVDGVWM
HHHHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AMPISNIALCLIVVPLVWLDVKARARKFGPTTTEAVIATA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECC
>Mature Secondary Structure
MLAQSIENNSNDSISRTFWRYTLPAIAAMLVNGLYQIVDGIFIGHYIGYEGLAAINMAWP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VIYFMVGFGIMIGMGSGSLLSIQRGKGDTSAAPTILTTSLLSMLALAVASSAILSILSTF
HHHHHHHHHHHEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLEAQGGAGTTLVMAQDYISVFSWGTAITIIASALPLLIRNDESPNIATGLMVLGAFINI
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHH
ALDYLLIGVFEFGLLGAAIATITAQLTVCILGLVYFCSRISNISWPSKFRYFNASFAKQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEECHHHHHHH
VLLGSSSLFMYLYTSFVFALHNRLFIEYGTPLTVGAFAIVGYLMVLYYLVSEGIAEGLQP
HEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVSYYYGAEQHANINKMLKLSIKVTLIAGTSWILLLNAIPETMVKLFNSSDSELIATAVD
CHHHHCCCCCCCCHHHEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GIRMHLFAMPLDGFIVLSSVYFMATNQGVKALVIACGNMLIQLPFLMILPKFFGVDGVWM
HHHHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AMPISNIALCLIVVPLVWLDVKARARKFGPTTTEAVIATA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA