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The map label for this gene is nifM [H]

Identifier: 167622122

GI number: 167622122

Start: 213950

End: 214765

Strand: Direct

Name: nifM [H]

Synonym: Shal_0181

Alternate gene names: 167622122

Gene position: 213950-214765 (Clockwise)

Preceding gene: 167622121

Following gene: 167622129

Centisome position: 4.09

GC content: 46.32

Gene sequence:

>816_bases
ATGGGTTCTTGTGGACAACATGCATCAGCGACTCCTTCTGAACAGAAGTTGCCAATCATTAGCGTGAATGGCGTTACCAT
TAAAGAAGAAGTGCTTGCGAACGAACTGCAGTATCACTCAAATAGTGATTTTGACGTAGTGGTTCAACAGGCAGGGCAAA
CGTTGGTTATTCGTCAGTTGTTGATTGAGCAAGCGAAACAAAATGGTGTGGATGTTACTGCCGATAATGAGGAGCAGGGT
ATCGGACAGCTATTGGCAGATAAAGTCGTTTATCAAGAGCCTAGCGAAGAGGATTGCCTGCGCTATTTTCAAAATAACCG
AGAAAAATTTGTCACCGCTCCGCTATTGGAGGTTGACCATATTTTACTTCCGGCTTCAGCAGAAGATGAAGAGGCCAAGG
AAGTTGCTAGACAAAATGCTGAAAACATATTGGTACAGTTATCACAAGACATTAGCTGTTTCGCCGAGTTAGCGAAAAAG
TACTCTGCTTGTCCCTCAAAAGAAACGGGCGGCTCGCTTGGGCAGATCAGTAGTGGCCAGACGGTGCCGGAGTTTGAACA
GCAACTGATGCAACATGGTGAAGGACTGGTTGAGCAGCCACTGGCTTCACGCTACGGTTTTCATGTCGTGAATATTGCCA
GGAAAGTGGATGGCAAGCAGCTCGACTACAACATGGTTGCCGACAAGGTTAAAGGTTACTTAGTTCACCGAGCTTCTAGA
CTCGCCATCCAAGCCTATATCCATGGGCTGGTAGAGGTTGCCGAAATCGAAGGGATAGAGGTGGGTTTTGCACCTGAGCT
AAATATTCATCTATAG

Upstream 100 bases:

>100_bases
TGAGCCCTTTTTTTAGTAATTAACACATTTTTATTTAGCGGGATTGAGAAGAGCAGATCGAGTCTTCCGCCCTAAAACAA
AAAGACAAGGTAATTTTCTT

Downstream 100 bases:

>100_bases
GCTTTAATCCTATTACTCAACTGTCGTTTGGGTATAACCGCATGTCTCAGCCCCTACCGTTAATAACGTAGGGGTTTTTT
TCTCTAAATGATCCCACCGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: peptidylproline (omega=0) [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGSCGQHASATPSEQKLPIISVNGVTIKEEVLANELQYHSNSDFDVVVQQAGQTLVIRQLLIEQAKQNGVDVTADNEEQG
IGQLLADKVVYQEPSEEDCLRYFQNNREKFVTAPLLEVDHILLPASAEDEEAKEVARQNAENILVQLSQDISCFAELAKK
YSACPSKETGGSLGQISSGQTVPEFEQQLMQHGEGLVEQPLASRYGFHVVNIARKVDGKQLDYNMVADKVKGYLVHRASR
LAIQAYIHGLVEVAEIEGIEVGFAPELNIHL

Sequences:

>Translated_271_residues
MGSCGQHASATPSEQKLPIISVNGVTIKEEVLANELQYHSNSDFDVVVQQAGQTLVIRQLLIEQAKQNGVDVTADNEEQG
IGQLLADKVVYQEPSEEDCLRYFQNNREKFVTAPLLEVDHILLPASAEDEEAKEVARQNAENILVQLSQDISCFAELAKK
YSACPSKETGGSLGQISSGQTVPEFEQQLMQHGEGLVEQPLASRYGFHVVNIARKVDGKQLDYNMVADKVKGYLVHRASR
LAIQAYIHGLVEVAEIEGIEVGFAPELNIHL
>Mature_270_residues
GSCGQHASATPSEQKLPIISVNGVTIKEEVLANELQYHSNSDFDVVVQQAGQTLVIRQLLIEQAKQNGVDVTADNEEQGI
GQLLADKVVYQEPSEEDCLRYFQNNREKFVTAPLLEVDHILLPASAEDEEAKEVARQNAENILVQLSQDISCFAELAKKY
SACPSKETGGSLGQISSGQTVPEFEQQLMQHGEGLVEQPLASRYGFHVVNIARKVDGKQLDYNMVADKVKGYLVHRASRL
AIQAYIHGLVEVAEIEGIEVGFAPELNIHL

Specific function: Required for the activation and stabilization of the iron-component (nifH) of nitrogenase. Probable PPIase [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014282
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 29796; Mature: 29665

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSCGQHASATPSEQKLPIISVNGVTIKEEVLANELQYHSNSDFDVVVQQAGQTLVIRQL
CCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHH
LIEQAKQNGVDVTADNEEQGIGQLLADKVVYQEPSEEDCLRYFQNNREKFVTAPLLEVDH
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHEEECCHHHHHH
ILLPASAEDEEAKEVARQNAENILVQLSQDISCFAELAKKYSACPSKETGGSLGQISSGQ
EEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TVPEFEQQLMQHGEGLVEQPLASRYGFHVVNIARKVDGKQLDYNMVADKVKGYLVHRASR
CCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LAIQAYIHGLVEVAEIEGIEVGFAPELNIHL
HHHHHHHHHHHHHHHHCCEEECCCCCCEEEC
>Mature Secondary Structure 
GSCGQHASATPSEQKLPIISVNGVTIKEEVLANELQYHSNSDFDVVVQQAGQTLVIRQL
CCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHH
LIEQAKQNGVDVTADNEEQGIGQLLADKVVYQEPSEEDCLRYFQNNREKFVTAPLLEVDH
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHEEECCHHHHHH
ILLPASAEDEEAKEVARQNAENILVQLSQDISCFAELAKKYSACPSKETGGSLGQISSGQ
EEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TVPEFEQQLMQHGEGLVEQPLASRYGFHVVNIARKVDGKQLDYNMVADKVKGYLVHRASR
CCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LAIQAYIHGLVEVAEIEGIEVGFAPELNIHL
HHHHHHHHHHHHHHHHCCEEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Peptidoproline (omega=180) [C]

Specific reaction: Peptidoproline (omega=180) = peptidylproline (omega=0) [C]

General reaction: Rotation (Single bond) [C]

Inhibitor: cyclosporins [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1885524 [H]