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The map label for this gene is ilvE [H]

Identifier: 167040722

GI number: 167040722

Start: 2108684

End: 2109559

Strand: Reverse

Name: ilvE [H]

Synonym: Teth514_2099

Alternate gene names: 167040722

Gene position: 2109559-2108684 (Counterclockwise)

Preceding gene: 167040723

Following gene: 167040721

Centisome position: 85.85

GC content: 35.5

Gene sequence:

>876_bases
ATGGGGTTAGTATATGTGAATGGAGAATTTGTAGACAGTGAGAAAGCTTCAGTCTCGGTTTTTGACCATGGCTATCTTTA
TGGGGACGGTATTTTTGAGGGCATAAGGGCTTATGATGGAGTTATATTCAAACTTGATGAGCACTTAAAAAGACTTTATA
GTATGGCAAAAGCCCTTCTTCTCGACATTCCTATGACGATAGAAGAGATGAAAGAAAAAGTTGTGGAAACGGTAAGAGTT
AATAATTTAAGGGATGCCTATATAAGGCTTGTAGTGTCAAGAGGAAAAGGTGATTTAGGCCTTGACCCATATAAATGTCC
TAAACCCACAGTCGTAATAATAGCTGATAAGATTACTTTATATCCTGAATCTATGTATCAAAACGGTTTAAAAATTATTA
CCTCTACTTATAGAAGAAATTCTATTCAGGCTTTAGATCCCCAGATAAAGTCATTAAATTATTTAAATAATATTCTTGCA
AAAATTGAAGCAGTAAAAGCTGGGTATCCTGAAGCTCTTATACTAAACCAAGAAGGATATGTGGCTGAATGTACTGGTGA
CAATATTTTTATAGTTTCAAATGGCACCTTGTATTCTCCTCCTTCGGCAGTAGGAGCATTAGGAGGAATTACAAGGGCTA
CTGTAATTGATATAGCAAAGCAATTAGGAATCCCTTTTGAAGAAAGGTATTTTTCCTTGTTTAACGTGTATACTGCAGAT
GAATGTTTCTTGACAGGTACAGCTGCTGAAGCAATACCAGTGGTAGAAGTAGATCATAGGGTAATAGGAGATGGAAAACC
TGGTCCCATAACGAAAAAGATAATAGAAGAGTTTAGAAAACTTACTACTGCTTTAGGAACAAAGGTTTATGAATAA

Upstream 100 bases:

>100_bases
TCATTTTGGGGCTTTTTGTTTTTTATATTACATTGACTAAACTCTTTTAAAGTGATAAAATTTTGCTAAATTAATTTGAA
GTAAAGGAGGAGTCATAAGT

Downstream 100 bases:

>100_bases
GAATTGCATGGATGACTTCCATGCAATTTCTTATAAAGAAGGGATGATTTTTATGACTGAAAAGCTTTTTTATGAAAATA
ACTATGTTACCTAGTTTGAT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MGLVYVNGEFVDSEKASVSVFDHGYLYGDGIFEGIRAYDGVIFKLDEHLKRLYSMAKALLLDIPMTIEEMKEKVVETVRV
NNLRDAYIRLVVSRGKGDLGLDPYKCPKPTVVIIADKITLYPESMYQNGLKIITSTYRRNSIQALDPQIKSLNYLNNILA
KIEAVKAGYPEALILNQEGYVAECTGDNIFIVSNGTLYSPPSAVGALGGITRATVIDIAKQLGIPFEERYFSLFNVYTAD
ECFLTGTAAEAIPVVEVDHRVIGDGKPGPITKKIIEEFRKLTTALGTKVYE

Sequences:

>Translated_291_residues
MGLVYVNGEFVDSEKASVSVFDHGYLYGDGIFEGIRAYDGVIFKLDEHLKRLYSMAKALLLDIPMTIEEMKEKVVETVRV
NNLRDAYIRLVVSRGKGDLGLDPYKCPKPTVVIIADKITLYPESMYQNGLKIITSTYRRNSIQALDPQIKSLNYLNNILA
KIEAVKAGYPEALILNQEGYVAECTGDNIFIVSNGTLYSPPSAVGALGGITRATVIDIAKQLGIPFEERYFSLFNVYTAD
ECFLTGTAAEAIPVVEVDHRVIGDGKPGPITKKIIEEFRKLTTALGTKVYE
>Mature_290_residues
GLVYVNGEFVDSEKASVSVFDHGYLYGDGIFEGIRAYDGVIFKLDEHLKRLYSMAKALLLDIPMTIEEMKEKVVETVRVN
NLRDAYIRLVVSRGKGDLGLDPYKCPKPTVVIIADKITLYPESMYQNGLKIITSTYRRNSIQALDPQIKSLNYLNNILAK
IEAVKAGYPEALILNQEGYVAECTGDNIFIVSNGTLYSPPSAVGALGGITRATVIDIAKQLGIPFEERYFSLFNVYTADE
CFLTGTAAEAIPVVEVDHRVIGDGKPGPITKKIIEEFRKLTTALGTKVYE

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=288, Percent_Identity=37.8472222222222, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787338, Length=261, Percent_Identity=26.8199233716475, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32206; Mature: 32074

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVYVNGEFVDSEKASVSVFDHGYLYGDGIFEGIRAYDGVIFKLDEHLKRLYSMAKALL
CEEEEECCEEECCCCCEEEEEECCEEECCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHH
LDIPMTIEEMKEKVVETVRVNNLRDAYIRLVVSRGKGDLGLDPYKCPKPTVVIIADKITL
HCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCEEE
YPESMYQNGLKIITSTYRRNSIQALDPQIKSLNYLNNILAKIEAVKAGYPEALILNQEGY
CCHHHHHCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
VAECTGDNIFIVSNGTLYSPPSAVGALGGITRATVIDIAKQLGIPFEERYFSLFNVYTAD
EEEECCCEEEEEECCEEECCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEECC
ECFLTGTAAEAIPVVEVDHRVIGDGKPGPITKKIIEEFRKLTTALGTKVYE
CEEEECCHHHCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLVYVNGEFVDSEKASVSVFDHGYLYGDGIFEGIRAYDGVIFKLDEHLKRLYSMAKALL
EEEEECCEEECCCCCEEEEEECCEEECCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHH
LDIPMTIEEMKEKVVETVRVNNLRDAYIRLVVSRGKGDLGLDPYKCPKPTVVIIADKITL
HCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCEEE
YPESMYQNGLKIITSTYRRNSIQALDPQIKSLNYLNNILAKIEAVKAGYPEALILNQEGY
CCHHHHHCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
VAECTGDNIFIVSNGTLYSPPSAVGALGGITRATVIDIAKQLGIPFEERYFSLFNVYTAD
EEEECCCEEEEEECCEEECCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEECC
ECFLTGTAAEAIPVVEVDHRVIGDGKPGPITKKIIEEFRKLTTALGTKVYE
CEEEECCHHHCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]