Click here to switch to the map view.

The map label for this gene is engA [H]

Identifier: 167040606

GI number: 167040606

Start: 1994907

End: 1996226

Strand: Reverse

Name: engA [H]

Synonym: Teth514_1983

Alternate gene names: 167040606

Gene position: 1996226-1994907 (Counterclockwise)

Preceding gene: 167040607

Following gene: 167040605

Centisome position: 81.24

GC content: 34.02

Gene sequence:

>1320_bases
ATGGCAGGTGCAATGGTGAGTATTGTAGGTAGGCCAAATGTGGGTAAATCTACTCTTTTTAATAAGATTATGGGAAAGAG
AATTTCTATTGTTGAAGACAAACCAGGAGTTACAAGGGATAGAATATACGGTAATGCAGAATGGCTGGACAAAAAATTTA
TATTAGTAGACACAGGAGGATTAGACCCAAATGCTGAAGATATTCTCTTTTCAAAAGTTCGTTTACAAGTGGAAGCAGCA
ATTGATACTTCTGACGTAATATTATTTTTAGTTGATGCAAAAGAAGGTTTAATGCCAGAAGATGAAGAAATAGCAAACAT
TTTAAGAAGAGCAAAAAAAGAAGTTATTTTGGTTTGCAACAAGGTGGACAGTTTTAAAGAAATGCCTCCTACTTATTATG
ACTTTTTTAGTCTTGGTTTAGGCAATCCCATTCCAATTTCAGCGTCAAATGGGTTGGGCATCGGAGAACTTTTAGACGAA
GTAGTAAAAAGATTGCCACAGGAAGAGTTAGAATACACTGAAGAGACAATTAAAATTGCTGTTATTGGCAAACCTAATGT
GGGGAAATCCTCACTAGTTAACAAAATATTAGGAGAAGAAAGGGTAATAGTCAGTAACATACCTGGCACTACACGGGATG
CAATAGATACTCCTTTTTCAAAAGATGGGAAGAACTATGTTCTTATTGATACAGCAGGGATACGTAGAAAAAGTAGAATT
AGCGAATCTATAGAAAGGTACAGTGTACTAAGAGCTTTAGCTGCAATTGAAAGGTCTGATATATGCCTTTTGATGATAGA
TGCTACAGAAGGTCCAACAGAACAGGACACTAAAATAGCAGGATATGCGTTTGAGAATGGAAAAGGAATCATCATAGTTG
TTAATAAATGGGATGCAATAAAAAAAGATAATAATACTGTTAATGAGTATACTAAGATGGTAAGAGAAAAACTATCTTTT
ATATCTTTTGCTCCTATACTATTTATTTCAGCGAAAACAGGGCAAAGAGTACACAGAGTTTTAGAGACTGTAGATAAAGT
GTGGGAGGAATATAATAAAAGAATTACTACTGGTCTTTTAAATAATGTGCTAAATGAAGCTATACTTATGTTTCCGCCAC
CTGCTGATAAGGGCAAACCATTAAAAGTATATTATACTTCACAAGTAGGAATTAAGCCACCTTCTTTTGTAGTATTTGTC
AATGAACCAGAGCTGATGCATTTTTCCTATTTAAGATTTATTGAGAATACATTAAGACAAAATTTTGGCTTTGAAGGGGT
ACCTATTGTGATTTCTACTAAAAAAAGAGGAGAAAATTAA

Upstream 100 bases:

>100_bases
ACAGTTGAAGAAGTAGAAAAGGAACTTGGTGCACAAATTATGGTTTCACCAGTGGATGGAAAAGAATTTTTACAAAAGAT
ACAGAGTGGAAGGTGATAGT

Downstream 100 bases:

>100_bases
AAGAGAAAGGGGGGGAAATATGTACGCTGTTTTAACGGCCATCATTGCTTATTTGATTGGTTGCATAAACAATGCATATA
TTTTTACAAAATACACGCGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGGLDPNAEDILFSKVRLQVEAA
IDTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCNKVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDE
VVKRLPQEELEYTEETIKIAVIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRI
SESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAIKKDNNTVNEYTKMVREKLSF
ISFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLLNNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFV
NEPELMHFSYLRFIENTLRQNFGFEGVPIVISTKKRGEN

Sequences:

>Translated_439_residues
MAGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGGLDPNAEDILFSKVRLQVEAA
IDTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCNKVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDE
VVKRLPQEELEYTEETIKIAVIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRI
SESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAIKKDNNTVNEYTKMVREKLSF
ISFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLLNNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFV
NEPELMHFSYLRFIENTLRQNFGFEGVPIVISTKKRGEN
>Mature_438_residues
AGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGGLDPNAEDILFSKVRLQVEAAI
DTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCNKVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDEV
VKRLPQEELEYTEETIKIAVIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRIS
ESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAIKKDNNTVNEYTKMVREKLSFI
SFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLLNNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFVN
EPELMHFSYLRFIENTLRQNFGFEGVPIVISTKKRGEN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Homo sapiens, GI193082988, Length=94, Percent_Identity=41.4893617021277, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI193082991, Length=94, Percent_Identity=41.4893617021277, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082120, Length=465, Percent_Identity=40.8602150537634, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1788919, Length=178, Percent_Identity=34.2696629213483, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=43.1578947368421, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17507259, Length=115, Percent_Identity=34.7826086956522, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=226, Percent_Identity=35.3982300884956, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45550813, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49051; Mature: 48920

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGG
CCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHCCCCHHHCCCEEEEEECCC
LDPNAEDILFSKVRLQVEAAIDTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCN
CCCCHHHHHHHHHEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEC
KVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDEVVKRLPQEELEYTEETIKIA
CHHHHHHCCCHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEE
VIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRI
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHH
SESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAI
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEECCCCC
KKDNNTVNEYTKMVREKLSFISFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLL
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFVNEPELMHFSYLRFIENTLRQ
HHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
NFGFEGVPIVISTKKRGEN
CCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
AGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGG
CCCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHCCCCHHHCCCEEEEEECCC
LDPNAEDILFSKVRLQVEAAIDTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCN
CCCCHHHHHHHHHEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEC
KVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDEVVKRLPQEELEYTEETIKIA
CHHHHHHCCCHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEE
VIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRI
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHH
SESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAI
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEECCCCC
KKDNNTVNEYTKMVREKLSFISFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLL
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFVNEPELMHFSYLRFIENTLRQ
HHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
NFGFEGVPIVISTKKRGEN
CCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA