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The map label for this gene is gpsA [H]

Identifier: 167040604

GI number: 167040604

Start: 1993283

End: 1994275

Strand: Reverse

Name: gpsA [H]

Synonym: Teth514_1981

Alternate gene names: 167040604

Gene position: 1994275-1993283 (Counterclockwise)

Preceding gene: 167040605

Following gene: 167040603

Centisome position: 81.16

GC content: 36.86

Gene sequence:

>993_bases
ATGAAAATATCAGTATTAGGTGCGGGAAGTTGGGGAACAGCTATAGCGATACACTTAAACCGACTTGGGCATCAAATTAC
ATTGTGGCTGAGAGATAAAAATCAGTTTGAGGAAATTGTGTCTACTCGTCACAATAAAAAATATCTTGATGTTGATATTC
CTCAAGAAATTTCCATTACTACTGATTTAAAAGAGGCAGTAACTAACTCTGAAATAGTAGTAATCGCAGTACCTTCTCAT
GCTGTGAGAGAGATATCGGAAAAATTAAAAGAGGTAGCTGATAAAAACTTTATTGTGGTAAATCTTGCAAAGGGAATAGA
GACTTCCACTTTAAAAAGAATGTCTGAAGTCATAAAAGAATATCTTTCAAATGATGTAGTTGTTTTGTCAGGTCCTAGTC
ATGCTGAGGAAGTAGTCAGGCAAATTCCTACAGCCTGTGTTTTAGCCTCTTTAAATGTTAAAGCTTGTGAGGTAGTGCAA
GATGCCTTTATGGATGAAAACTTTAGGTTGTATATAAACAAGGACGTTGTGGGAGTGGAATTAGGAGGATCATTAAAGAA
TATTATAGCCTTGGGAGCTGGAATTTCAGACGGGCTTGGATTTGGCGATAATACCAAAGCTGCTCTTATGACAAGAGGTC
TTGCGGAAATTACTCGTTTGGGTGTCGCGTTAGGTTCTGATCCGTTGACGTTTTTAGGTTTGGCAGGTGTAGGAGACCTC
ATTGTCACTTGTACCAGCATGCTTTCACGAAATAGAAGAGCAGGGATACTTATAGGTAAAGGTAAAAGTTTAGAAGAAGC
ATTAAAAGAGATAGGAATGGTAGTAGAAGGAGTTAATACTACAAAATCCGCCTACAGACTTTCTCAAATTCATAAAATAG
AAATGCCAATAACTAAAGAAATTTATTCCATACTTTTTGAGGGTAAAAATCCCTATGAGGCTGTTTATAGCCTTATGACG
AGAGATAAAAAACATGAATTGCACGGTATTTGA

Upstream 100 bases:

>100_bases
AGCAATTTTCCAACACCGTTCTAATATAAAACGTTTGCTGGCGGGAACAGAATCCAAGCTGGGACAAAAGACGGAAATAA
AATGAGAAAGGAAAGTGGTC

Downstream 100 bases:

>100_bases
TCTCCGGTTTTCCGGAGATTTTATTATATTTCAATATTTTTTACATATAAATGTACTGTTAAAGCATATATATATGAGTG
AGAAGAAAAGGATATGGGGA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKISVLGAGSWGTAIAIHLNRLGHQITLWLRDKNQFEEIVSTRHNKKYLDVDIPQEISITTDLKEAVTNSEIVVIAVPSH
AVREISEKLKEVADKNFIVVNLAKGIETSTLKRMSEVIKEYLSNDVVVLSGPSHAEEVVRQIPTACVLASLNVKACEVVQ
DAFMDENFRLYINKDVVGVELGGSLKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVALGSDPLTFLGLAGVGDL
IVTCTSMLSRNRRAGILIGKGKSLEEALKEIGMVVEGVNTTKSAYRLSQIHKIEMPITKEIYSILFEGKNPYEAVYSLMT
RDKKHELHGI

Sequences:

>Translated_330_residues
MKISVLGAGSWGTAIAIHLNRLGHQITLWLRDKNQFEEIVSTRHNKKYLDVDIPQEISITTDLKEAVTNSEIVVIAVPSH
AVREISEKLKEVADKNFIVVNLAKGIETSTLKRMSEVIKEYLSNDVVVLSGPSHAEEVVRQIPTACVLASLNVKACEVVQ
DAFMDENFRLYINKDVVGVELGGSLKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVALGSDPLTFLGLAGVGDL
IVTCTSMLSRNRRAGILIGKGKSLEEALKEIGMVVEGVNTTKSAYRLSQIHKIEMPITKEIYSILFEGKNPYEAVYSLMT
RDKKHELHGI
>Mature_330_residues
MKISVLGAGSWGTAIAIHLNRLGHQITLWLRDKNQFEEIVSTRHNKKYLDVDIPQEISITTDLKEAVTNSEIVVIAVPSH
AVREISEKLKEVADKNFIVVNLAKGIETSTLKRMSEVIKEYLSNDVVVLSGPSHAEEVVRQIPTACVLASLNVKACEVVQ
DAFMDENFRLYINKDVVGVELGGSLKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVALGSDPLTFLGLAGVGDL
IVTCTSMLSRNRRAGILIGKGKSLEEALKEIGMVVEGVNTTKSAYRLSQIHKIEMPITKEIYSILFEGKNPYEAVYSLMT
RDKKHELHGI

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=344, Percent_Identity=31.6860465116279, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24307999, Length=348, Percent_Identity=29.5977011494253, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=42.9878048780488, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI32564399, Length=344, Percent_Identity=32.2674418604651, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32564403, Length=363, Percent_Identity=31.6804407713499, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193210136, Length=353, Percent_Identity=32.0113314447592, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=28.7323943661972, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193210134, Length=341, Percent_Identity=27.8592375366569, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324513, Length=339, Percent_Identity=26.8436578171091, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320181, Length=339, Percent_Identity=29.2035398230088, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136202, Length=327, Percent_Identity=31.4984709480122, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136200, Length=327, Percent_Identity=31.4984709480122, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136204, Length=327, Percent_Identity=31.4984709480122, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI22026922, Length=287, Percent_Identity=27.1777003484321, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45551945, Length=284, Percent_Identity=27.4647887323944, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281362270, Length=284, Percent_Identity=27.4647887323944, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648969, Length=237, Percent_Identity=28.2700421940928, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36009; Mature: 36009

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVLGAGSWGTAIAIHLNRLGHQITLWLRDKNQFEEIVSTRHNKKYLDVDIPQEISIT
CEEEEEECCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCEEC
TDLKEAVTNSEIVVIAVPSHAVREISEKLKEVADKNFIVVNLAKGIETSTLKRMSEVIKE
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
YLSNDVVVLSGPSHAEEVVRQIPTACVLASLNVKACEVVQDAFMDENFRLYINKDVVGVE
HHCCCEEEEECCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCEEEEE
LGGSLKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVALGSDPLTFLGLAGVGDL
ECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHH
IVTCTSMLSRNRRAGILIGKGKSLEEALKEIGMVVEGVNTTKSAYRLSQIHKIEMPITKE
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
IYSILFEGKNPYEAVYSLMTRDKKHELHGI
HHHHHHCCCCHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MKISVLGAGSWGTAIAIHLNRLGHQITLWLRDKNQFEEIVSTRHNKKYLDVDIPQEISIT
CEEEEEECCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCEEC
TDLKEAVTNSEIVVIAVPSHAVREISEKLKEVADKNFIVVNLAKGIETSTLKRMSEVIKE
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
YLSNDVVVLSGPSHAEEVVRQIPTACVLASLNVKACEVVQDAFMDENFRLYINKDVVGVE
HHCCCEEEEECCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCEEEEE
LGGSLKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVALGSDPLTFLGLAGVGDL
ECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHH
IVTCTSMLSRNRRAGILIGKGKSLEEALKEIGMVVEGVNTTKSAYRLSQIHKIEMPITKE
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
IYSILFEGKNPYEAVYSLMTRDKKHELHGI
HHHHHHCCCCHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA