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The map label for this gene is phoB [H]

Identifier: 167040602

GI number: 167040602

Start: 1989499

End: 1990299

Strand: Reverse

Name: phoB [H]

Synonym: Teth514_1977

Alternate gene names: 167040602

Gene position: 1990299-1989499 (Counterclockwise)

Preceding gene: 167040603

Following gene: 167040601

Centisome position: 81.0

GC content: 34.71

Gene sequence:

>801_bases
ATGGAGGAAAGGAAAGATAGTAAAAATATTCTAGTAATAGATGATTCTGTATTAATACGGCTTATGGCTAAAAATATATT
AGAGGCAGAAGGATATAACGTTGAAGCTGCAGCTACCGCTGAAGAAGCGATGCTGAAAGTAAAAAATAGAAAAGAATTAT
TTGATTTAGTAATTGTAGACATTAATCTGCCGAATCAGAATGGTTTTGAATTTATACGGAAATTAAAGTCAGAGGAAAAA
TACAGAGACATCCCGGTAATGATATTGAGCGCAGATGCTACAGCACCTTCAATTAGACAGGCAGTAGAAGCTGGTGCGGT
AGAATATCTCATTAAGCCCTTTAAAGCAGCTGAGCTTGTAAAACGTGTAGTAAAACTAATAGGATACATTAAAGAAGAAG
ATCACTATCCGGAACTTAAAGAGCTGCTAAAAAAAGAAATAAACCGGGCCAAGAGAAGCAATGTAAATCTTTCTTTAGTT
CTGGCACAATGCGAAGGAAAAATCAGAGTAGAAATTTCAAAAATAGCAAAACAGGTAAAGAACAGACTTCGCGACATAGA
TACAGTATTTGAGATTGATAAAAATACTTTGGCTTTAGTTCTTCCTGTTACAGGAGCTAATGGCGCAGTGGTTGTAATAA
AAAAAGTTAAAGGTAAACTGCCGGGTAAATGGTATTTTGGTATAAGTACATATCCCGATAACGGCAAAGATGAAGAGGAG
CTAATTAATTTTGCAAAAGAAAGCTTAATGAAAGAAATATCGAATTTAAAACAAGAGACGGCAGAAAGGAAAGAAATATA
G

Upstream 100 bases:

>100_bases
GGAAGAAATTGTGTAAAAAGCGAATAAAAAATGGAAATGAAATATAATGTGGGAGGAGGATAAAAAGAGAGGCTTGTAAT
GAAGCCTCACTAAAAGAACT

Downstream 100 bases:

>100_bases
GAGTTATACAGACAGTAATTTTTTGGTATTATATTTTTAGACAAAAAAATAATAAAATTGCTATTGCAAAGGAAATGTTA
AAAAAAGCTGCTAAATTAAA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEERKDSKNILVIDDSVLIRLMAKNILEAEGYNVEAAATAEEAMLKVKNRKELFDLVIVDINLPNQNGFEFIRKLKSEEK
YRDIPVMILSADATAPSIRQAVEAGAVEYLIKPFKAAELVKRVVKLIGYIKEEDHYPELKELLKKEINRAKRSNVNLSLV
LAQCEGKIRVEISKIAKQVKNRLRDIDTVFEIDKNTLALVLPVTGANGAVVVIKKVKGKLPGKWYFGISTYPDNGKDEEE
LINFAKESLMKEISNLKQETAERKEI

Sequences:

>Translated_266_residues
MEERKDSKNILVIDDSVLIRLMAKNILEAEGYNVEAAATAEEAMLKVKNRKELFDLVIVDINLPNQNGFEFIRKLKSEEK
YRDIPVMILSADATAPSIRQAVEAGAVEYLIKPFKAAELVKRVVKLIGYIKEEDHYPELKELLKKEINRAKRSNVNLSLV
LAQCEGKIRVEISKIAKQVKNRLRDIDTVFEIDKNTLALVLPVTGANGAVVVIKKVKGKLPGKWYFGISTYPDNGKDEEE
LINFAKESLMKEISNLKQETAERKEI
>Mature_266_residues
MEERKDSKNILVIDDSVLIRLMAKNILEAEGYNVEAAATAEEAMLKVKNRKELFDLVIVDINLPNQNGFEFIRKLKSEEK
YRDIPVMILSADATAPSIRQAVEAGAVEYLIKPFKAAELVKRVVKLIGYIKEEDHYPELKELLKKEINRAKRSNVNLSLV
LAQCEGKIRVEISKIAKQVKNRLRDIDTVFEIDKNTLALVLPVTGANGAVVVIKKVKGKLPGKWYFGISTYPDNGKDEEE
LINFAKESLMKEISNLKQETAERKEI

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=115, Percent_Identity=37.3913043478261, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=35.042735042735, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=32.7731092436975, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=30.2521008403361, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=33.0578512396694, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=29.6610169491525, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790552, Length=120, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30126; Mature: 30126

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERKDSKNILVIDDSVLIRLMAKNILEAEGYNVEAAATAEEAMLKVKNRKELFDLVIVD
CCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEE
INLPNQNGFEFIRKLKSEEKYRDIPVMILSADATAPSIRQAVEAGAVEYLIKPFKAAELV
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVVKLIGYIKEEDHYPELKELLKKEINRAKRSNVNLSLVLAQCEGKIRVEISKIAKQVK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHHHH
NRLRDIDTVFEIDKNTLALVLPVTGANGAVVVIKKVKGKLPGKWYFGISTYPDNGKDEEE
HHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCHHH
LINFAKESLMKEISNLKQETAERKEI
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEERKDSKNILVIDDSVLIRLMAKNILEAEGYNVEAAATAEEAMLKVKNRKELFDLVIVD
CCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEE
INLPNQNGFEFIRKLKSEEKYRDIPVMILSADATAPSIRQAVEAGAVEYLIKPFKAAELV
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVVKLIGYIKEEDHYPELKELLKKEINRAKRSNVNLSLVLAQCEGKIRVEISKIAKQVK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHHHH
NRLRDIDTVFEIDKNTLALVLPVTGANGAVVVIKKVKGKLPGKWYFGISTYPDNGKDEEE
HHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCHHH
LINFAKESLMKEISNLKQETAERKEI
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2115874; 10984043 [H]