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The map label for this gene is spoIIAB

Identifier: 167040196

GI number: 167040196

Start: 1580596

End: 1581027

Strand: Direct

Name: spoIIAB

Synonym: Teth514_1558

Alternate gene names: 167040196

Gene position: 1580596-1581027 (Clockwise)

Preceding gene: 167040195

Following gene: 167040197

Centisome position: 64.32

GC content: 35.65

Gene sequence:

>432_bases
ATGGAATACACAAACATGATGGAGTTAAATTTTTTAAGTAAGTCGCAAAATGAGTCTTTTGCAAGGACTGTTGTTGCAGC
TTTTGCTGCTCAACTAGATCCGACAATTGAGGAAATTGCAGATATAAAAACTGCTGTTTCAGAAGCAGTTACTAACTGCA
TAATTCACGGATATGAGAATAAAATCGGCATCATTACTATTAAAGCTTTTATTTCAGGTAACAAAATAACAATTGAAGTC
ATAGATGAGGGAAAAGGGATTGAAGATATTGAGAAAGCTATGCAACCTCTTTTTACTACTCGCTTAGAAGAAGAGCGAGC
AGGAATGGGTTTTACTGTCATGCAGACCTTTATGGATGAATTAGAAGTTGAATCAACTCCAGGAAAGGGAACTCTTGTCC
GAATGACAAAATATATAGGGTCTGATAAATGA

Upstream 100 bases:

>100_bases
CAATTACATAAAATTATTGAAGTTTCTGGGTTGTTGCGTATAATTAAATGTTATAATGACATTGAAGAAGCCTTAAAGGA
AATATAGAAGGGGGATTATC

Downstream 100 bases:

>100_bases
GGTGACTTTATGAAAGAAGGGAATTTTGAAAAAAGTGATGAGAATTTGGAATTGATAAGAGCAGCACAAAAGAATGATAA
AGAAAGCTTGGAAAAATTAA

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYENKIGIITIKAFISGNKITIEV
IDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDELEVESTPGKGTLVRMTKYIGSDK

Sequences:

>Translated_143_residues
MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYENKIGIITIKAFISGNKITIEV
IDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDELEVESTPGKGTLVRMTKYIGSDK
>Mature_143_residues
MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYENKIGIITIKAFISGNKITIEV
IDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDELEVESTPGKGTLVRMTKYIGSDK

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP2AB_THEP3 (B0K9G3)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665112.1
- ProteinModelPortal:   B0K9G3
- SMR:   B0K9G3
- GeneID:   5875326
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1121
- HOGENOM:   HBG425195
- OMA:   IIHAYEN
- ProtClustDB:   PRK03660
- BioCyc:   TPSE340099:TETH39_1121-MONOMER
- HAMAP:   MF_00637
- InterPro:   IPR010194
- InterPro:   IPR003594
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- TIGRFAMs:   TIGR01925

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.11.1

Molecular weight: Translated: 15881; Mature: 15881

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYEN
CCCCCHHEEHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KIGIITIKAFISGNKITIEVIDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDE
CEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LEVESTPGKGTLVRMTKYIGSDK
HCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYEN
CCCCCHHEEHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KIGIITIKAFISGNKITIEVIDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDE
CEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LEVESTPGKGTLVRMTKYIGSDK
HCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA