Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 167040155

GI number: 167040155

Start: 1545467

End: 1545982

Strand: Direct

Name: aroK [H]

Synonym: Teth514_1517

Alternate gene names: 167040155

Gene position: 1545467-1545982 (Clockwise)

Preceding gene: 167040154

Following gene: 167040156

Centisome position: 62.89

GC content: 33.53

Gene sequence:

>516_bases
ATGAAAAACATCGTTTTAACGGGTTTTATGGCTACCGGGAAAACTACTGTTGGCAAAAAAGTAGCTACCACCATGTCCTT
TGGTTTTATAGATACGGATAAAATGATTGAAAAAATGGCAAATATGACTGTTTCAGATATTTTTGAAAAATATGGAGAAA
ATTATTTTAGAAAATTAGAAAAAGCAGCGGTTAAAAAAGCAGCCCGATTAAAAAATTTTGTCATAGCTACAGGAGGGGGA
GTTGTATTAAACCCCTCAAATATTGTACAATTAAGAAAAAATGGTGTAGTCATTTGCTTTGTAGCCAGGCCAGAAATTAT
ATTGAGGAATATAGGAAAGAATAAAGACAGGCCTCTTCTTATGGTGGATAATCCAGAAGAGAAAATAAGACAGCTTCTAA
AAGAAAGAGAGCCTTTTTATAGGTTTGCCGACTATACTATTGATGTATCCGATATGACAATAGATGAAGTAGCAGAGGAA
GTTATAAAGGCTTACATTAGACTTAAGAAAGGATGA

Upstream 100 bases:

>100_bases
TAAAATCTTCAGAATATAGATGTAAATAAAATAATAAATGATACTATAGAAAAAGTTTTGAAAGAGAAAATACCTTCATT
GCCTTAGGGAGGAAATATTC

Downstream 100 bases:

>100_bases
GAGGATTGGCTATAAAATTTGGACCATCTGGGAATTCTGATAGTTTCTACAAAGAAGGGCATAAATCTTCTTTAGAAATG
CCTGAATGGCTCCATAACAT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLEKAAVKKAARLKNFVIATGGG
VVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLLMVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEE
VIKAYIRLKKG

Sequences:

>Translated_171_residues
MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLEKAAVKKAARLKNFVIATGGG
VVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLLMVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEE
VIKAYIRLKKG
>Mature_171_residues
MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLEKAAVKKAARLKNFVIATGGG
VVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLLMVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEE
VIKAYIRLKKG

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=34.7560975609756, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786587, Length=154, Percent_Identity=32.4675324675325, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19374; Mature: 19374

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLE
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KAAVKKAARLKNFVIATGGGVVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLL
HHHHHHHHHHHHEEEEECCCEEECCHHHEEEECCCEEEEEECCCHHHHHHCCCCCCCCEE
MVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEEVIKAYIRLKKG
EECCCHHHHHHHHHHCCCCEEHHCCEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLE
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KAAVKKAARLKNFVIATGGGVVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLL
HHHHHHHHHHHHEEEEECCCEEECCHHHEEEECCCEEEEEECCCHHHHHHCCCCCCCCEE
MVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEEVIKAYIRLKKG
EECCCHHHHHHHHHHCCCCEEHHCCEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA