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The map label for this gene is cymR [H]

Identifier: 167040123

GI number: 167040123

Start: 1518552

End: 1519001

Strand: Direct

Name: cymR [H]

Synonym: Teth514_1485

Alternate gene names: 167040123

Gene position: 1518552-1519001 (Clockwise)

Preceding gene: 167040122

Following gene: 167040124

Centisome position: 61.8

GC content: 39.78

Gene sequence:

>450_bases
GTGAAACTATCTACAAAAGGTCGATATGGGATACAAGCTATGTTTGAATTAGCCCTTTACTACGGGGAAGGCCCCATTTC
TTTAAAGACAATTGCCGAAAATGAAGGACTTTCTGAGCATTATCTAGAACAGCTTATAGCAATCCTTAGAAAAGCTGACC
TTGTGAAAAGTGTCAGAGGAGCACAAGGGGGATATATGCTAGCGGCTCCTCCTGATAAGATAACTGTTGGAGATGTGATA
AGAACGTTGGAAGGTTCATTGGCTCCTGCAGATTGCGTTTTGGAAGATACTCCTTTTGAATGCAGCAGAGCAGGAGGTTG
TCCGACGAAGTTGGTGATGGAAAGAATAAGAGACAGTATAAATAAAGTGATAGACTCTATTACTTTACAGGATATGGTGG
ATGATTACAGGCGATTAAATCAAAAAAGTGCTTTTATGTATTACATTTAG

Upstream 100 bases:

>100_bases
AAAGAATTATAGAAAATTAAGTGTTGACAACCACTTTTTTAAGTGGTATTCTTTTTGGTGAAATCCGGGTAAAATAGTAG
GAATTCAGGGGTGGATAATC

Downstream 100 bases:

>100_bases
GGAAATAATAATTTTAGGACTTTTAAAGGAGGATTTTATATATAACATGGAGATAAACAATAGAGTAGCAATTGGAATGA
GTGGAGGAGTAGATAGCTCT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLIAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVLEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVDDYRRLNQKSAFMYYI

Sequences:

>Translated_149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLIAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVLEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVDDYRRLNQKSAFMYYI
>Mature_149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLIAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVLEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVDDYRRLNQKSAFMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=140, Percent_Identity=36.4285714285714, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16556; Mature: 16556

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLIAILRKADLVKSVRG
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQGGYMLAAPPDKITVGDVIRTLEGSLAPADCVLEDTPFECSRAGGCPTKLVMERIRDSI
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
NKVIDSITLQDMVDDYRRLNQKSAFMYYI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLIAILRKADLVKSVRG
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQGGYMLAAPPDKITVGDVIRTLEGSLAPADCVLEDTPFECSRAGGCPTKLVMERIRDSI
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
NKVIDSITLQDMVDDYRRLNQKSAFMYYI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]