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The map label for this gene is trpB [H]

Identifier: 167040117

GI number: 167040117

Start: 1511700

End: 1513094

Strand: Direct

Name: trpB [H]

Synonym: Teth514_1479

Alternate gene names: 167040117

Gene position: 1511700-1513094 (Clockwise)

Preceding gene: 167040116

Following gene: 167040118

Centisome position: 61.52

GC content: 37.85

Gene sequence:

>1395_bases
ATGAGTAGGTATAAGCATGTAATGGCTAGGAAAAACGAAATAATGAAAAGATCTTTGGGAATAGATTATGAAAAATTTGA
ATCAGGTGGAATTGCTTTTGAATATGAAAAAATGATGAAAGAAACAGGTTACACCTTAGAAGAAATTGTTAAAATACAAA
GGGAAGCAAATGTAGGAAATACTCCTCTTATAGAGTTAAAAAACTTGACAGAATTAGCGAGAAAAGTTTCGCCAACAGGA
AAAGCTGCCAGAATCTTTATAAAAGATGAAGCTTGTAACCATTCAGGAAGCTTTAAAGAAAGGCGGGCTAGTGTTTCTAT
ATATCACGCAAAACAAAAGGGATATAAGGGAGTCATAGCTGCCACTAGTGGTAATTACGGAGCAGCAGTGGCTTCACAAG
CTGCCATGAAAGGTTTAAAATGCATCGTAGTGCAAGAAGCTTATGATAGTAGAGGTATAGGGCAGCCAGAAATATTGGAA
AAAGGAAGAAAGTGTGAAACATTTGGAGCGGAAGTCATACAACTAACTGTTGGACCGGAATTATTTTATGTAAACTTGAT
GTTATTAGAAGAGACGGGATATTTTAATGCTTCTTTGTACACTCCTTTTGGAGTTGCTGGTATTGAAACATTGGGATATG
AAATAGCTCAGCAAGTAAAAGAGAGGACTGGTAAGTTTCCTGATGTTGTTGTAGCCACCCATGCTGGTGGAGGCAATTTG
ACGGGTACTGCAAGAGGACTTATGAAAGCGGGAGCAGTAAACACAAAAATATACGGCGTGAGCGTTGATTTAACAGGGCT
TCATATGGCTTCAGACAAGGATTTTAACAGAAAATCTTTTACAACAGGACATACAGGATTTGGAATCCCATTTGCAACTT
GGCCGGATAGAGCAGATGTGCCTCGAAATGCTGCAAGGCCTTTAAGGTACATGGATGGGTATTACCTTGTCAAGCAAGGG
GAAGTCTTTTACATGACAGAGCTTTTAGCTCAATTAGAAGGTTTAGAAAGAGGACCAGCGGGAAATACCTCTTTAGCGGC
AGCTTTCAGTTTGGCACAGCAAATGGAAAATGACCAGATAATAGTGGTGCAGGAGACAGAATATACAGGAGCAGGTAAAA
ATCCAACGGCTCAGCTTACTTTTGCTATGCAAAATGGTATAAAAATTCTAGTAGGAAATCCTGATGATGAGATACCAGGA
CAAAACATAATTTTACCTGAACATCCTTCTATGATAAAGGCGAGAGAAGTTTATCTTTTGAATTTGAAAAAGTCTTACAT
TAAAAACTGCATTCAACACTTTGGATTGCCTAAAGATGATAGAGACATTAAATTTTTGGCTGAAGATACCAAGTCCAGTC
AGGAATTTGTAAGAGAAATAATTTCAGAATTATAG

Upstream 100 bases:

>100_bases
AAATCAATCCACGGCATATTCACGATTTTGGCAATCCAATTCCTGAGCTTATAAAAGCAGGTATAAAAGCAAGAGAGATA
TTGTATGGCGGTGAAGAAGA

Downstream 100 bases:

>100_bases
GATGGGGTGATAATGTGAAAAGAGTAGACGATTTTGAAACGAGGAGTAAACACCTTCAACACATGACAGATGAAGAATTA
GACGCATATTTCTGGGAATT

Product: pyridoxal-5'-phosphate-dependent enzyme subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSRYKHVMARKNEIMKRSLGIDYEKFESGGIAFEYEKMMKETGYTLEEIVKIQREANVGNTPLIELKNLTELARKVSPTG
KAARIFIKDEACNHSGSFKERRASVSIYHAKQKGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILE
KGRKCETFGAEVIQLTVGPELFYVNLMLLEETGYFNASLYTPFGVAGIETLGYEIAQQVKERTGKFPDVVVATHAGGGNL
TGTARGLMKAGAVNTKIYGVSVDLTGLHMASDKDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQG
EVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAMQNGIKILVGNPDDEIPG
QNIILPEHPSMIKAREVYLLNLKKSYIKNCIQHFGLPKDDRDIKFLAEDTKSSQEFVREIISEL

Sequences:

>Translated_464_residues
MSRYKHVMARKNEIMKRSLGIDYEKFESGGIAFEYEKMMKETGYTLEEIVKIQREANVGNTPLIELKNLTELARKVSPTG
KAARIFIKDEACNHSGSFKERRASVSIYHAKQKGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILE
KGRKCETFGAEVIQLTVGPELFYVNLMLLEETGYFNASLYTPFGVAGIETLGYEIAQQVKERTGKFPDVVVATHAGGGNL
TGTARGLMKAGAVNTKIYGVSVDLTGLHMASDKDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQG
EVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAMQNGIKILVGNPDDEIPG
QNIILPEHPSMIKAREVYLLNLKKSYIKNCIQHFGLPKDDRDIKFLAEDTKSSQEFVREIISEL
>Mature_463_residues
SRYKHVMARKNEIMKRSLGIDYEKFESGGIAFEYEKMMKETGYTLEEIVKIQREANVGNTPLIELKNLTELARKVSPTGK
AARIFIKDEACNHSGSFKERRASVSIYHAKQKGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEK
GRKCETFGAEVIQLTVGPELFYVNLMLLEETGYFNASLYTPFGVAGIETLGYEIAQQVKERTGKFPDVVVATHAGGGNLT
GTARGLMKAGAVNTKIYGVSVDLTGLHMASDKDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQGE
VFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAMQNGIKILVGNPDDEIPGQ
NIILPEHPSMIKAREVYLLNLKKSYIKNCIQHFGLPKDDRDIKFLAEDTKSSQEFVREIISEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321412, Length=333, Percent_Identity=28.5285285285285, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 51207; Mature: 51076

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYKHVMARKNEIMKRSLGIDYEKFESGGIAFEYEKMMKETGYTLEEIVKIQREANVGN
CCHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCC
TPLIELKNLTELARKVSPTGKAARIFIKDEACNHSGSFKERRASVSIYHAKQKGYKGVIA
CCEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHCEEEEEEECCCCCCEEEE
ATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETFGAEVIQLTVGPE
EECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCE
LFYVNLMLLEETGYFNASLYTPFGVAGIETLGYEIAQQVKERTGKFPDVVVATHAGGGNL
EEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
TGTARGLMKAGAVNTKIYGVSVDLTGLHMASDKDFNRKSFTTGHTGFGIPFATWPDRADV
CHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRNAARPLRYMDGYYLVKQGEVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQI
CCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCE
IVVQETEYTGAGKNPTAQLTFAMQNGIKILVGNPDDEIPGQNIILPEHPSMIKAREVYLL
EEEEECCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCCCCCCCEEEEEEEE
NLKKSYIKNCIQHFGLPKDDRDIKFLAEDTKSSQEFVREIISEL
ECHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SRYKHVMARKNEIMKRSLGIDYEKFESGGIAFEYEKMMKETGYTLEEIVKIQREANVGN
CHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCC
TPLIELKNLTELARKVSPTGKAARIFIKDEACNHSGSFKERRASVSIYHAKQKGYKGVIA
CCEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHCEEEEEEECCCCCCEEEE
ATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETFGAEVIQLTVGPE
EECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCE
LFYVNLMLLEETGYFNASLYTPFGVAGIETLGYEIAQQVKERTGKFPDVVVATHAGGGNL
EEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
TGTARGLMKAGAVNTKIYGVSVDLTGLHMASDKDFNRKSFTTGHTGFGIPFATWPDRADV
CHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRNAARPLRYMDGYYLVKQGEVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQI
CCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCE
IVVQETEYTGAGKNPTAQLTFAMQNGIKILVGNPDDEIPGQNIILPEHPSMIKAREVYLL
EEEEECCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCCCCCCCEEEEEEEE
NLKKSYIKNCIQHFGLPKDDRDIKFLAEDTKSSQEFVREIISEL
ECHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA