Click here to switch to the map view.

The map label for this gene is lytB [H]

Identifier: 167040080

GI number: 167040080

Start: 1476731

End: 1479019

Strand: Direct

Name: lytB [H]

Synonym: Teth514_1440

Alternate gene names: 167040080

Gene position: 1476731-1479019 (Clockwise)

Preceding gene: 167040079

Following gene: 167040081

Centisome position: 60.1

GC content: 34.08

Gene sequence:

>2289_bases
ATGAATAACAAAAAAGTAATTAGCGTTTTACTTTCTTCAACTTTAGTTTTGTCATTAGCTAATAGTGCTTATGCTGCTAC
AATTTTAAAGTATGGAATGCGCAGCCCAGAAGTTAGGCATCTACAGCAAAATCTCAATAAGGCAGGTTACTTTGTTACTG
CTAATCCTACTGATTATTTTGGACCAGCTACTAAGAATGCTGTTATGCGTTTGCAGAAGGATTATAATTTAGTACCGGAT
GGTATTTATGGGCCGTTAACAGAAAAAGCTCTTATGGATAAATTAAATGCTATTTCTAAGGCAACAACTCAAACTTCTAA
TACTTCACTGCAAACTCAAAGTACAGTGACAAGGACTTTGAAGTATGGAATGCAAGGGAACGATGTAAAAGAGCTTCAAA
ATGCTCTTGCAAAATTAGGATATTTTAATACTACACCGACAGGCTATTTTGGTTCGATAACACGGGATGCAGTTATAAAA
TTTCAAAAGGCAAATAATTTGACTCCGGATGGAATTGTGGGACCTCTCACACAAAAAGCTATTTCGGAGAAGTTAAATGT
AAGTTTACCTTCCAGAGGAGATGTAAATAGAAGTACTAACACGACACAGAACTCCAGCAATTCAAACCAAACTCAAAGTA
CAGTGACAAGGACTTTGAAGTATGGAATGCAAGGGAACGATGTAAAAGAGCTTCAAAATGCTCTTGCAAAATTAGGATAT
TTTAATACTACACCGACAGGCTATTTTGGTTCGATAACACGGGATGCAGTTATAAAATTTCAAAAGGCAAATAATTTGAC
TCCGGATGGAATTGTGGGACCTCTAACACAAAAAACAATACAAGGTTTATTGGCTGGAAAAGACCAGCAAGCATCTCAAC
CTACAGACTCACCAAAAATTCAGTATCCCAGTGGGTTTTCAAGGAATATGAAAAAAGGGGATACTGGCGATGATGTAAAA
TTATTACAAACATTACTTAAGGAAATAGGCTATTATACAAAAGATATTACAGGAACTTATGATGATAATACATTAAATGC
AGTAATGGATTTTCAAAAATATTATTCTTTAGCTGTTGACGGAATTGCTGGTATAAATACTATCACAAAAGTAATAGAAA
TAAACAATCAGGTGAAAGCTGTAAAAGGTTTTTATGTCCAAGGAAAAGGCGGATATGGCCATGGAGTGGGTATGACTCAA
TTTGGTGCAAAGGGTATGGCGGAACAAGAATATAAATATGATGAGATAATTAAATACTATTATACAGGTGTCAATATAGA
AAAACGTAATACGGATAATGTTAATATCAAAGTAAAGATTTCTTTAGATTTAGGAAGTCCAGATATAAACATTACCAGCG
ACCAGCCGTATAGTGTAGTATACAAAACAAAAGATAACGATACAGAACAAATAGTAGAAAACCAAATAGCGTGTCCAGCA
CAATCTACAACATCTTTCAAATATATGGATGGAAATATTGTAATTACCAATGATAAAGTAATAGATGATAGTACTCAACT
TCCACAAACGATAGTAAGCATAGATGCTGTTAGAGTAATACCAAGTGACACGGGAGTACTGTCATACATAAATAAAGGTA
ATCCACTTCCTTATGCAGGCGAATTTAAGATATATCCAAATAATAGTTCTAAGAATTTGGATTTAATAAACATATTGCCT
TTAGAAGAATATTTAAGAGGTGTAGTACCTGCAGAAATGCCTTCTTCTTGGCATGAGGAAGCTTTAAAAGCTCAAACATT
AGCAGCCAGGACATACGCGTTAAGACGGATTAGTGATAAAAAGATTTTTGATGTATATGATTCTACATTATCACAAGCAT
ATAAAGGACTTTCTGTAGTAAATGATAAGGTCGATAATTTGATAAAAGCTACTAAAGGTGAAGTTGTAACTTACAATGGT
GGCTTAGCAGATACTGTGTACAGTGCATCTGCAGGAGGATATACAGTGGATTCGACTTTTGCATGGGGTGGTAGCGATGT
TCCTTATCTAAAAGGAAAACCCGATCCTTATGATAATTCTAAATATGCTACATACTGGTGGAATGTAAATATTACAAGAG
ATCAAATATCGTCAGCATATCCTCAAGTAGGTGTTGTTTTAAATGTAGAGATTACAAATAAGATGTTTGATAGGCCAGTA
GAGCTCAAAATTACAGGAACAAAAGGTACTATTGTAGTAAAAAATAAAGATTTCAGAGATGCCATAGAAAAGGCCGTAGG
TAAAAAGTTATTTATCTCAGAGTATTATACTATTAGTTTACAAAAATAA

Upstream 100 bases:

>100_bases
GATTGGTGTCTCTTACTTTATATACATAATCTAAAAAAACGTAATTTTTAATGTCTTCCTAAGTTGAAACACTTGGGAAG
AAGGGAGAGGAGAAGCTATA

Downstream 100 bases:

>100_bases
AAAATAATATAAAGAGGGAGCCTTTTAAAATAGAAAGAAGGCTCCTTTTTATCTGGAACCATAATTTAAAAAGAATTGCT
TTTTGTCTAAAAATAAAATA

Product: SpoIID/LytB domain-containing protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP76; CWBP76; Modifier protein of major autolysin [H]

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MNNKKVISVLLSSTLVLSLANSAYAATILKYGMRSPEVRHLQQNLNKAGYFVTANPTDYFGPATKNAVMRLQKDYNLVPD
GIYGPLTEKALMDKLNAISKATTQTSNTSLQTQSTVTRTLKYGMQGNDVKELQNALAKLGYFNTTPTGYFGSITRDAVIK
FQKANNLTPDGIVGPLTQKAISEKLNVSLPSRGDVNRSTNTTQNSSNSNQTQSTVTRTLKYGMQGNDVKELQNALAKLGY
FNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKTIQGLLAGKDQQASQPTDSPKIQYPSGFSRNMKKGDTGDDVK
LLQTLLKEIGYYTKDITGTYDDNTLNAVMDFQKYYSLAVDGIAGINTITKVIEINNQVKAVKGFYVQGKGGYGHGVGMTQ
FGAKGMAEQEYKYDEIIKYYYTGVNIEKRNTDNVNIKVKISLDLGSPDINITSDQPYSVVYKTKDNDTEQIVENQIACPA
QSTTSFKYMDGNIVITNDKVIDDSTQLPQTIVSIDAVRVIPSDTGVLSYINKGNPLPYAGEFKIYPNNSSKNLDLINILP
LEEYLRGVVPAEMPSSWHEEALKAQTLAARTYALRRISDKKIFDVYDSTLSQAYKGLSVVNDKVDNLIKATKGEVVTYNG
GLADTVYSASAGGYTVDSTFAWGGSDVPYLKGKPDPYDNSKYATYWWNVNITRDQISSAYPQVGVVLNVEITNKMFDRPV
ELKITGTKGTIVVKNKDFRDAIEKAVGKKLFISEYYTISLQK

Sequences:

>Translated_762_residues
MNNKKVISVLLSSTLVLSLANSAYAATILKYGMRSPEVRHLQQNLNKAGYFVTANPTDYFGPATKNAVMRLQKDYNLVPD
GIYGPLTEKALMDKLNAISKATTQTSNTSLQTQSTVTRTLKYGMQGNDVKELQNALAKLGYFNTTPTGYFGSITRDAVIK
FQKANNLTPDGIVGPLTQKAISEKLNVSLPSRGDVNRSTNTTQNSSNSNQTQSTVTRTLKYGMQGNDVKELQNALAKLGY
FNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKTIQGLLAGKDQQASQPTDSPKIQYPSGFSRNMKKGDTGDDVK
LLQTLLKEIGYYTKDITGTYDDNTLNAVMDFQKYYSLAVDGIAGINTITKVIEINNQVKAVKGFYVQGKGGYGHGVGMTQ
FGAKGMAEQEYKYDEIIKYYYTGVNIEKRNTDNVNIKVKISLDLGSPDINITSDQPYSVVYKTKDNDTEQIVENQIACPA
QSTTSFKYMDGNIVITNDKVIDDSTQLPQTIVSIDAVRVIPSDTGVLSYINKGNPLPYAGEFKIYPNNSSKNLDLINILP
LEEYLRGVVPAEMPSSWHEEALKAQTLAARTYALRRISDKKIFDVYDSTLSQAYKGLSVVNDKVDNLIKATKGEVVTYNG
GLADTVYSASAGGYTVDSTFAWGGSDVPYLKGKPDPYDNSKYATYWWNVNITRDQISSAYPQVGVVLNVEITNKMFDRPV
ELKITGTKGTIVVKNKDFRDAIEKAVGKKLFISEYYTISLQK
>Mature_762_residues
MNNKKVISVLLSSTLVLSLANSAYAATILKYGMRSPEVRHLQQNLNKAGYFVTANPTDYFGPATKNAVMRLQKDYNLVPD
GIYGPLTEKALMDKLNAISKATTQTSNTSLQTQSTVTRTLKYGMQGNDVKELQNALAKLGYFNTTPTGYFGSITRDAVIK
FQKANNLTPDGIVGPLTQKAISEKLNVSLPSRGDVNRSTNTTQNSSNSNQTQSTVTRTLKYGMQGNDVKELQNALAKLGY
FNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKTIQGLLAGKDQQASQPTDSPKIQYPSGFSRNMKKGDTGDDVK
LLQTLLKEIGYYTKDITGTYDDNTLNAVMDFQKYYSLAVDGIAGINTITKVIEINNQVKAVKGFYVQGKGGYGHGVGMTQ
FGAKGMAEQEYKYDEIIKYYYTGVNIEKRNTDNVNIKVKISLDLGSPDINITSDQPYSVVYKTKDNDTEQIVENQIACPA
QSTTSFKYMDGNIVITNDKVIDDSTQLPQTIVSIDAVRVIPSDTGVLSYINKGNPLPYAGEFKIYPNNSSKNLDLINILP
LEEYLRGVVPAEMPSSWHEEALKAQTLAARTYALRRISDKKIFDVYDSTLSQAYKGLSVVNDKVDNLIKATKGEVVTYNG
GLADTVYSASAGGYTVDSTFAWGGSDVPYLKGKPDPYDNSKYATYWWNVNITRDQISSAYPQVGVVLNVEITNKMFDRPV
ELKITGTKGTIVVKNKDFRDAIEKAVGKKLFISEYYTISLQK

Specific function: Possibly involved in cell wall metabolism during spore formation. Enhances the amidase activity approximately threefold [H]

COG id: COG2385

COG function: function code D; Sporulation protein and related proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133 [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR013486
- InterPro:   IPR013693 [H]

Pfam domain/function: PF04122 CW_binding_2; PF08486 SpoIID [H]

EC number: NA

Molecular weight: Translated: 83884; Mature: 83884

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKKVISVLLSSTLVLSLANSAYAATILKYGMRSPEVRHLQQNLNKAGYFVTANPTDYF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCC
GPATKNAVMRLQKDYNLVPDGIYGPLTEKALMDKLNAISKATTQTSNTSLQTQSTVTRTL
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
KYGMQGNDVKELQNALAKLGYFNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKA
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCHHHHHH
ISEKLNVSLPSRGDVNRSTNTTQNSSNSNQTQSTVTRTLKYGMQGNDVKELQNALAKLGY
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
FNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKTIQGLLAGKDQQASQPTDSPKI
CCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
QYPSGFSRNMKKGDTGDDVKLLQTLLKEIGYYTKDITGTYDDNTLNAVMDFQKYYSLAVD
ECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHH
GIAGINTITKVIEINNQVKAVKGFYVQGKGGYGHGVGMTQFGAKGMAEQEYKYDEIIKYY
HHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCHHHCCHHHHHHHH
YTGVNIEKRNTDNVNIKVKISLDLGSPDINITSDQPYSVVYKTKDNDTEQIVENQIACPA
HCCCEEECCCCCCEEEEEEEEEECCCCCEEECCCCCEEEEEEECCCCHHHHHHHHCCCCC
QSTTSFKYMDGNIVITNDKVIDDSTQLPQTIVSIDAVRVIPSDTGVLSYINKGNPLPYAG
CCCCEEEEECCEEEEECCEEECCCHHHHHHHHHHEEEEEECCCCCHHHHHCCCCCCCCCC
EFKIYPNNSSKNLDLINILPLEEYLRGVVPAEMPSSWHEEALKAQTLAARTYALRRISDK
EEEEEECCCCCCEEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KIFDVYDSTLSQAYKGLSVVNDKVDNLIKATKGEVVTYNGGLADTVYSASAGGYTVDSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHEECCCCCEEECCEE
AWGGSDVPYLKGKPDPYDNSKYATYWWNVNITRDQISSAYPQVGVVLNVEITNKMFDRPV
ECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHHHCCCCCEEEEEEEEECHHHHCCCE
ELKITGTKGTIVVKNKDFRDAIEKAVGKKLFISEYYTISLQK
EEEEECCCCEEEEECCCHHHHHHHHHCCEEEEEEEEEEEEEC
>Mature Secondary Structure
MNNKKVISVLLSSTLVLSLANSAYAATILKYGMRSPEVRHLQQNLNKAGYFVTANPTDYF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCC
GPATKNAVMRLQKDYNLVPDGIYGPLTEKALMDKLNAISKATTQTSNTSLQTQSTVTRTL
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
KYGMQGNDVKELQNALAKLGYFNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKA
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCHHHHHH
ISEKLNVSLPSRGDVNRSTNTTQNSSNSNQTQSTVTRTLKYGMQGNDVKELQNALAKLGY
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
FNTTPTGYFGSITRDAVIKFQKANNLTPDGIVGPLTQKTIQGLLAGKDQQASQPTDSPKI
CCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
QYPSGFSRNMKKGDTGDDVKLLQTLLKEIGYYTKDITGTYDDNTLNAVMDFQKYYSLAVD
ECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHH
GIAGINTITKVIEINNQVKAVKGFYVQGKGGYGHGVGMTQFGAKGMAEQEYKYDEIIKYY
HHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCHHHCCHHHHHHHH
YTGVNIEKRNTDNVNIKVKISLDLGSPDINITSDQPYSVVYKTKDNDTEQIVENQIACPA
HCCCEEECCCCCCEEEEEEEEEECCCCCEEECCCCCEEEEEEECCCCHHHHHHHHCCCCC
QSTTSFKYMDGNIVITNDKVIDDSTQLPQTIVSIDAVRVIPSDTGVLSYINKGNPLPYAG
CCCCEEEEECCEEEEECCEEECCCHHHHHHHHHHEEEEEECCCCCHHHHHCCCCCCCCCC
EFKIYPNNSSKNLDLINILPLEEYLRGVVPAEMPSSWHEEALKAQTLAARTYALRRISDK
EEEEEECCCCCCEEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KIFDVYDSTLSQAYKGLSVVNDKVDNLIKATKGEVVTYNGGLADTVYSASAGGYTVDSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHEECCCCCEEECCEE
AWGGSDVPYLKGKPDPYDNSKYATYWWNVNITRDQISSAYPQVGVVLNVEITNKMFDRPV
ECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHHHCCCCCEEEEEEEEECHHHHCCCE
ELKITGTKGTIVVKNKDFRDAIEKAVGKKLFISEYYTISLQK
EEEEECCCCEEEEECCCHHHHHHHHHCCEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1357079; 1356138; 9384377 [H]