| Definition | Thermoanaerobacter sp. X514 chromosome, complete genome. |
|---|---|
| Accession | NC_010320 |
| Length | 2,457,259 |
Click here to switch to the map view.
The map label for this gene is pbpA [H]
Identifier: 167038911
GI number: 167038911
Start: 255763
End: 258252
Strand: Direct
Name: pbpA [H]
Synonym: Teth514_0242
Alternate gene names: 167038911
Gene position: 255763-258252 (Clockwise)
Preceding gene: 167038910
Following gene: 167038912
Centisome position: 10.41
GC content: 37.63
Gene sequence:
>2490_bases ATGGATAATAACGCAAATTTAAAGCGAAGTGAAAGGAGAAAACAGAAGGATAAAACTAAAAAGAAAAGCGTGGCAAAAAA CATAATAAAATTTGTCATATATACTTTTATAATTCTAATATTTGCAGCTGCTGGGGTTATTGGAGCTAAAGTATGGACAA TAATTAAAGATACTCCCGAGATATCTGAGGAAGCTTTAACAAAGCAAGCCCAATCTTCTATTGTTTATGCAGATAACGGA GAAGAAGTAGCAACTTTGTTTGGGGCAAGTAATAGGATATGGGTTCCATTAGACCAAATACCTAAAGATTTACAAAATGC TTTCGTTGCTATTGAGGACCAAAGATTTTATCAAAATAACTTAGGAATTGATCCAAAAAGAATCATTGGAGCTCTTATTG CAAATATTAAAGCGGGAGGTAAACCTGTTGAAGGTGCAAGTACTATAACTCAACAGCTTGTAAAAAATACCATGCTTTCC AGTGAAAAAACCCTTTCAAGAAAAATTAAAGAAGCGATTCTTGCTTGGAGACTGGAACAGAAATATTCAAAAGAACAAAT ACTAGAGGCTTATCTCAACACAATATACCTTGGAGGACCTAATGTAAATGCATATGGAGTGGAAGCAGCTGCAAGAGCTT ATTTCAACAAACATGTTAATGAGTTAGATTTAGCAGAAAGTGCTTTAATTGCTGGTATAACTAAGAACCCTTCCTTGTAT TCGCCTGCAGCTAACAAAGAAGCTGCAATAGAGAGGCAGCGTCTTGTTTTAAAAGAAATGCTTAAACAAGGGTACATTAC ACAAGAACAATACGATGAGGCTATTAATGAAAAGTTGGAGTTTGATATACATTATTCTGTTGTCAGCGATAAACATAAAT ATTTCATAGATCAAGTAAAAGAGGATGTGGCTAATGCTCTTTCACAAAAATTAAACATATCGTATGAAGAGGCTATGAAC AAAATATTCAATGGTGGTCTTAGAATTTACACGACAATGGATGTAAATATCCAAAATATTATGGAGGAAGCTTTCAAAAA CTCAAAACTTTTTCCGGCTGATTTAAAAGATAAAGAAGGCAACATTCGAATAGTTCAAGGTGCCATGGTAGTAATGGATT GGAGAACAGGAGAAGTTAAGGGTATAGTTGGGAGAAGAGAAACTGACGAAACTCAGGGCAAAGTAAGAGTTTTCAATTAT GCAACTACAGGTGGCAGACCACCTGGTTCTTCAATAAAGCCTATTACAGTTTATGGACCAGCATTGGAGAAAGGCTATAC AGCTGCTACAGTTGTTGATGATGTTCCTGTTTATTACAAACAGTGGAATTGGGAGCCTCACAATTATAGTAGAAATACTT ATAAAGGTCTTATGACCTTCAGAGAAGCTTTAAAAGTATCCCAAAATATACCTGCTGTAAGGATAGTTGTCGAGATGATA GGGCTTAATACTGCTGCAGAATATGGCAAAAAATTTGGGCTTGACATAACGGAAAGAATTGAAAAATCACCAGCTGCCCT TTCCCTTGGAGCAGGTGGAGAAGTTACCCCACTTCAAATGGCCGCTGCTTATGGAGCGATTGCAAATGGAGGAGTTTACA CATCTCCTATTACATTTACAAAGGTTACTGACTCAGAAGGGAATGTAATTTTAGAAAATAAACCTTCCCAGCATATAGTT TTAAGTCCGCAAAATGCTTATATATTAACAAATATGATGCAGGAGGTTGTAAAACCTGGAGGGACGGGTACGAATGCAAG ACTTCCTAATATGCCTGTTGCAGGGAAAACTGGTACAAATGAAAACTATTATGATGCCTGGTTTGCAGGGTTTACCCCTT ATTATTCGGCTTCAGTGTGGATGGGAACCGGGGAGAATATAGCAATGATATATGGTGGTAAAGGAGTTACAGGAGGTTCT TATCCAGCAATATTTTGGAAAACAGTGATGATGCAGATACACAAAAATTTACCATATAAAGATTTTGTAAGGCCACCAGG AATTATTTCTGTAACAGTATGTCGCGATTCAGGAGAACTTCCTACAGATTTGTGTCATTTGGATCCTAGAGGTGACAGAA CCTATACTGAAATTTTTGCACAGGGTACTCAACCCACAACTTATTGCACTGTTCATGTTACAGCAAAAATAAATTCTCAA AATGGTAAACTAGCAACGGATTTAACTCCTCCTGATTTGGTAAAAGATGCTGTGTTTATAGATCCACCAGGTAGAACACC AGCGCAGAATGCAGTTGCACTAGATGGAAAATATGTGGTTCCAAAAGAATACGATGATACTGTTCCGCCACCACAGAATT CTGATAATGGTGATGCTCCAGGGGATAATACTCAACCACCGCCCGCTAATAACGGTGGTACAGAGCAACCTCCTGGAGGA GAAACGACCAATCCGCCTCCTAACAATGGTAATTCTCAAACTAGTCCGCCTAGTAATAACCCTCCTTCCACAACAAATCC AATACCATGA
Upstream 100 bases:
>100_bases TTTGTTACAAATTGGACATAAAAATGGCCTGAATTTATGATATAATTTATATTAATCATTATATGCTTTCAGAAGAGTAC TTTAATATGGGGGATTTAAT
Downstream 100 bases:
>100_bases GAAAAAAGCATACTTGAAAGCATAGCTTTCAAGTATGCTTTTTTTATAAAATGTGCTATTATTAAATTAAGATATAGTTG GAGGAGTTAAATTGAAAAAG
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 829; Mature: 829
Protein sequence:
>829_residues MDNNANLKRSERRKQKDKTKKKSVAKNIIKFVIYTFIILIFAAAGVIGAKVWTIIKDTPEISEEALTKQAQSSIVYADNG EEVATLFGASNRIWVPLDQIPKDLQNAFVAIEDQRFYQNNLGIDPKRIIGALIANIKAGGKPVEGASTITQQLVKNTMLS SEKTLSRKIKEAILAWRLEQKYSKEQILEAYLNTIYLGGPNVNAYGVEAAARAYFNKHVNELDLAESALIAGITKNPSLY SPAANKEAAIERQRLVLKEMLKQGYITQEQYDEAINEKLEFDIHYSVVSDKHKYFIDQVKEDVANALSQKLNISYEEAMN KIFNGGLRIYTTMDVNIQNIMEEAFKNSKLFPADLKDKEGNIRIVQGAMVVMDWRTGEVKGIVGRRETDETQGKVRVFNY ATTGGRPPGSSIKPITVYGPALEKGYTAATVVDDVPVYYKQWNWEPHNYSRNTYKGLMTFREALKVSQNIPAVRIVVEMI GLNTAAEYGKKFGLDITERIEKSPAALSLGAGGEVTPLQMAAAYGAIANGGVYTSPITFTKVTDSEGNVILENKPSQHIV LSPQNAYILTNMMQEVVKPGGTGTNARLPNMPVAGKTGTNENYYDAWFAGFTPYYSASVWMGTGENIAMIYGGKGVTGGS YPAIFWKTVMMQIHKNLPYKDFVRPPGIISVTVCRDSGELPTDLCHLDPRGDRTYTEIFAQGTQPTTYCTVHVTAKINSQ NGKLATDLTPPDLVKDAVFIDPPGRTPAQNAVALDGKYVVPKEYDDTVPPPQNSDNGDAPGDNTQPPPANNGGTEQPPGG ETTNPPPNNGNSQTSPPSNNPPSTTNPIP
Sequences:
>Translated_829_residues MDNNANLKRSERRKQKDKTKKKSVAKNIIKFVIYTFIILIFAAAGVIGAKVWTIIKDTPEISEEALTKQAQSSIVYADNG EEVATLFGASNRIWVPLDQIPKDLQNAFVAIEDQRFYQNNLGIDPKRIIGALIANIKAGGKPVEGASTITQQLVKNTMLS SEKTLSRKIKEAILAWRLEQKYSKEQILEAYLNTIYLGGPNVNAYGVEAAARAYFNKHVNELDLAESALIAGITKNPSLY SPAANKEAAIERQRLVLKEMLKQGYITQEQYDEAINEKLEFDIHYSVVSDKHKYFIDQVKEDVANALSQKLNISYEEAMN KIFNGGLRIYTTMDVNIQNIMEEAFKNSKLFPADLKDKEGNIRIVQGAMVVMDWRTGEVKGIVGRRETDETQGKVRVFNY ATTGGRPPGSSIKPITVYGPALEKGYTAATVVDDVPVYYKQWNWEPHNYSRNTYKGLMTFREALKVSQNIPAVRIVVEMI GLNTAAEYGKKFGLDITERIEKSPAALSLGAGGEVTPLQMAAAYGAIANGGVYTSPITFTKVTDSEGNVILENKPSQHIV LSPQNAYILTNMMQEVVKPGGTGTNARLPNMPVAGKTGTNENYYDAWFAGFTPYYSASVWMGTGENIAMIYGGKGVTGGS YPAIFWKTVMMQIHKNLPYKDFVRPPGIISVTVCRDSGELPTDLCHLDPRGDRTYTEIFAQGTQPTTYCTVHVTAKINSQ NGKLATDLTPPDLVKDAVFIDPPGRTPAQNAVALDGKYVVPKEYDDTVPPPQNSDNGDAPGDNTQPPPANNGGTEQPPGG ETTNPPPNNGNSQTSPPSNNPPSTTNPIP >Mature_829_residues MDNNANLKRSERRKQKDKTKKKSVAKNIIKFVIYTFIILIFAAAGVIGAKVWTIIKDTPEISEEALTKQAQSSIVYADNG EEVATLFGASNRIWVPLDQIPKDLQNAFVAIEDQRFYQNNLGIDPKRIIGALIANIKAGGKPVEGASTITQQLVKNTMLS SEKTLSRKIKEAILAWRLEQKYSKEQILEAYLNTIYLGGPNVNAYGVEAAARAYFNKHVNELDLAESALIAGITKNPSLY SPAANKEAAIERQRLVLKEMLKQGYITQEQYDEAINEKLEFDIHYSVVSDKHKYFIDQVKEDVANALSQKLNISYEEAMN KIFNGGLRIYTTMDVNIQNIMEEAFKNSKLFPADLKDKEGNIRIVQGAMVVMDWRTGEVKGIVGRRETDETQGKVRVFNY ATTGGRPPGSSIKPITVYGPALEKGYTAATVVDDVPVYYKQWNWEPHNYSRNTYKGLMTFREALKVSQNIPAVRIVVEMI GLNTAAEYGKKFGLDITERIEKSPAALSLGAGGEVTPLQMAAAYGAIANGGVYTSPITFTKVTDSEGNVILENKPSQHIV LSPQNAYILTNMMQEVVKPGGTGTNARLPNMPVAGKTGTNENYYDAWFAGFTPYYSASVWMGTGENIAMIYGGKGVTGGS YPAIFWKTVMMQIHKNLPYKDFVRPPGIISVTVCRDSGELPTDLCHLDPRGDRTYTEIFAQGTQPTTYCTVHVTAKINSQ NGKLATDLTPPDLVKDAVFIDPPGRTPAQNAVALDGKYVVPKEYDDTVPPPQNSDNGDAPGDNTQPPPANNGGTEQPPGG ETTNPPPNNGNSQTSPPSNNPPSTTNPIP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=573, Percent_Identity=34.0314136125654, Blast_Score=226, Evalue=5e-60, Organism=Escherichia coli, GI87082258, Length=326, Percent_Identity=38.6503067484663, Blast_Score=204, Evalue=2e-53, Organism=Escherichia coli, GI1788867, Length=647, Percent_Identity=26.7387944358578, Blast_Score=139, Evalue=6e-34, Organism=Escherichia coli, GI1789601, Length=182, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=2e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 90976; Mature: 90976
Theoretical pI: Translated: 7.25; Mature: 7.25
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDNNANLKRSERRKQKDKTKKKSVAKNIIKFVIYTFIILIFAAAGVIGAKVWTIIKDTPE CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH ISEEALTKQAQSSIVYADNGEEVATLFGASNRIWVPLDQIPKDLQNAFVAIEDQRFYQNN HHHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHEEEEECCHHHHHC LGIDPKRIIGALIANIKAGGKPVEGASTITQQLVKNTMLSSEKTLSRKIKEAILAWRLEQ CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH KYSKEQILEAYLNTIYLGGPNVNAYGVEAAARAYFNKHVNELDLAESALIAGITKNPSLY HHCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCC SPAANKEAAIERQRLVLKEMLKQGYITQEQYDEAINEKLEFDIHYSVVSDKHKYFIDQVK CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHH EDVANALSQKLNISYEEAMNKIFNGGLRIYTTMDVNIQNIMEEAFKNSKLFPADLKDKEG HHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCC NIRIVQGAMVVMDWRTGEVKGIVGRRETDETQGKVRVFNYATTGGRPPGSSIKPITVYGP CEEEEECEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECC ALEKGYTAATVVDDVPVYYKQWNWEPHNYSRNTYKGLMTFREALKVSQNIPAVRIVVEMI CHHCCCEEEEEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH GLNTAAEYGKKFGLDITERIEKSPAALSLGAGGEVTPLQMAAAYGAIANGGVYTSPITFT CCCHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEECCEEEE KVTDSEGNVILENKPSQHIVLSPQNAYILTNMMQEVVKPGGTGTNARLPNMPVAGKTGTN EEECCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC ENYYDAWFAGFTPYYSASVWMGTGENIAMIYGGKGVTGGSYPAIFWKTVMMQIHKNLPYK CCCCHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHH DFVRPPGIISVTVCRDSGELPTDLCHLDPRGDRTYTEIFAQGTQPTTYCTVHVTAKINSQ HHCCCCCEEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECC NGKLATDLTPPDLVKDAVFIDPPGRTPAQNAVALDGKYVVPKEYDDTVPPPQNSDNGDAP CCEEEECCCCHHHHCCCEEECCCCCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCCC GDNTQPPPANNGGTEQPPGGETTNPPPNNGNSQTSPPSNNPPSTTNPIP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MDNNANLKRSERRKQKDKTKKKSVAKNIIKFVIYTFIILIFAAAGVIGAKVWTIIKDTPE CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH ISEEALTKQAQSSIVYADNGEEVATLFGASNRIWVPLDQIPKDLQNAFVAIEDQRFYQNN HHHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHEEEEECCHHHHHC LGIDPKRIIGALIANIKAGGKPVEGASTITQQLVKNTMLSSEKTLSRKIKEAILAWRLEQ CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH KYSKEQILEAYLNTIYLGGPNVNAYGVEAAARAYFNKHVNELDLAESALIAGITKNPSLY HHCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCC SPAANKEAAIERQRLVLKEMLKQGYITQEQYDEAINEKLEFDIHYSVVSDKHKYFIDQVK CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHH EDVANALSQKLNISYEEAMNKIFNGGLRIYTTMDVNIQNIMEEAFKNSKLFPADLKDKEG HHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCC NIRIVQGAMVVMDWRTGEVKGIVGRRETDETQGKVRVFNYATTGGRPPGSSIKPITVYGP CEEEEECEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECC ALEKGYTAATVVDDVPVYYKQWNWEPHNYSRNTYKGLMTFREALKVSQNIPAVRIVVEMI CHHCCCEEEEEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH GLNTAAEYGKKFGLDITERIEKSPAALSLGAGGEVTPLQMAAAYGAIANGGVYTSPITFT CCCHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEECCEEEE KVTDSEGNVILENKPSQHIVLSPQNAYILTNMMQEVVKPGGTGTNARLPNMPVAGKTGTN EEECCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC ENYYDAWFAGFTPYYSASVWMGTGENIAMIYGGKGVTGGSYPAIFWKTVMMQIHKNLPYK CCCCHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHH DFVRPPGIISVTVCRDSGELPTDLCHLDPRGDRTYTEIFAQGTQPTTYCTVHVTAKINSQ HHCCCCCEEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECC NGKLATDLTPPDLVKDAVFIDPPGRTPAQNAVALDGKYVVPKEYDDTVPPPQNSDNGDAP CCEEEECCCCHHHHCCCEEECCCCCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCCC GDNTQPPPANNGGTEQPPGGETTNPPPNNGNSQTSPPSNNPPSTTNPIP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA