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The map label for this gene is murQ

Identifier: 167038842

GI number: 167038842

Start: 174096

End: 175004

Strand: Direct

Name: murQ

Synonym: Teth514_0172

Alternate gene names: 167038842

Gene position: 174096-175004 (Clockwise)

Preceding gene: 167038841

Following gene: 167038843

Centisome position: 7.08

GC content: 33.0

Gene sequence:

>909_bases
ATGGATTTAGATAAACTTATAACGGAAGGAAGAAACCCTGATACACTTGATATTGATAGATTAAGTACAGAAGATATGTT
AAAAAAAATAAATAATGAAGATAAAAAAGTTCCAATAGCTGTTGAAAAAGAAATACCTAATATAGCAAAAGCTGTTGATA
TTATAGCAGAAAAATTAAAACAAGGAGGAAGACTTATATACATTGGTGCTGGTACAAGTGGAAGGCTGGGAATTCTCGAT
GCATCCGAATGCCCACCAACTTTTGGAGTAGATCCAGAAATGGTGCAAGGGATTATTGCAGGTGGAGATGTTGCAATAAG
AAGGTCAGTAGAAGATGCGGAAGACAAAGAAGACCTTGGTAAAGAAGATTTAAAGAAAAAGAATTTGTCAAGTAAGGATG
TTGTAGTAGGTATTGCAGCCAGTGGTCGGACGCCTTATGTATTAGGAGCACTTAGATATGCTAAAGAAGTTGGTGCACAT
ACAGTAGGGATATCCTGCAATCCGGATAGTGAGATGAAAAAAATAGTTGATATAATGATAGCGCCTGTTGTAGGGCCAGA
AGTAATTATGGGTTCTACCAGAATGAAAGCAGGAACTGCACAAAAATTAGTATTAAATATGCTATCTACAGGTGCTATGA
TAAAACTTGGTAAAGTTTACAGCAATTTAATGGTGGATGTAAAAGCTACAAATGAAAAATTAATTAACAGAGCAAAACGC
ATTGTAAAATTAGCAACGGATGCAGATGAAAAAGTAATTGAAAAAATACTTAAGGAAACTAATTATAATGTTAAATTAAC
AATTTTAATGATATTAACAGGACTTAACCAAAATAAAGCAAAAGAACTTTTAGATAGGTCTAATGGTTATATTGCAAAGG
CATTAATGCTTAATGAAAATAAGTCTTAA

Upstream 100 bases:

>100_bases
GAAAGAGTAAATGTGGTAGGACATATACCTGAAGAAGAACATATATTGGTAGATTTAATTAGACCGGGGACAAAATTTAA
ATTTAGAAAGGGTTGATACA

Downstream 100 bases:

>100_bases
GAATAAATTTGAAGAGAAATTGAATTTATTAGGAAGTTTTATTTAAACTGAAAGGCGGATTAGTTTCCGCCTTTTATAAA
AAATTTTTCGAAATCATATT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDLDKLITEGRNPDTLDIDRLSTEDMLKKINNEDKKVPIAVEKEIPNIAKAVDIIAEKLKQGGRLIYIGAGTSGRLGILD
ASECPPTFGVDPEMVQGIIAGGDVAIRRSVEDAEDKEDLGKEDLKKKNLSSKDVVVGIAASGRTPYVLGALRYAKEVGAH
TVGISCNPDSEMKKIVDIMIAPVVGPEVIMGSTRMKAGTAQKLVLNMLSTGAMIKLGKVYSNLMVDVKATNEKLINRAKR
IVKLATDADEKVIEKILKETNYNVKLTILMILTGLNQNKAKELLDRSNGYIAKALMLNENKS

Sequences:

>Translated_302_residues
MDLDKLITEGRNPDTLDIDRLSTEDMLKKINNEDKKVPIAVEKEIPNIAKAVDIIAEKLKQGGRLIYIGAGTSGRLGILD
ASECPPTFGVDPEMVQGIIAGGDVAIRRSVEDAEDKEDLGKEDLKKKNLSSKDVVVGIAASGRTPYVLGALRYAKEVGAH
TVGISCNPDSEMKKIVDIMIAPVVGPEVIMGSTRMKAGTAQKLVLNMLSTGAMIKLGKVYSNLMVDVKATNEKLINRAKR
IVKLATDADEKVIEKILKETNYNVKLTILMILTGLNQNKAKELLDRSNGYIAKALMLNENKS
>Mature_302_residues
MDLDKLITEGRNPDTLDIDRLSTEDMLKKINNEDKKVPIAVEKEIPNIAKAVDIIAEKLKQGGRLIYIGAGTSGRLGILD
ASECPPTFGVDPEMVQGIIAGGDVAIRRSVEDAEDKEDLGKEDLKKKNLSSKDVVVGIAASGRTPYVLGALRYAKEVGAH
TVGISCNPDSEMKKIVDIMIAPVVGPEVIMGSTRMKAGTAQKLVLNMLSTGAMIKLGKVYSNLMVDVKATNEKLINRAKR
IVKLATDADEKVIEKILKETNYNVKLTILMILTGLNQNKAKELLDRSNGYIAKALMLNENKS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=57.2881355932203, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_THEPX (B0K1N2)

Other databases:

- EMBL:   CP000923
- RefSeq:   YP_001661827.1
- ProteinModelPortal:   B0K1N2
- SMR:   B0K1N2
- GeneID:   5875683
- GenomeReviews:   CP000923_GR
- KEGG:   tex:Teth514_0172
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- ProtClustDB:   PRK05441
- BioCyc:   TSP1755:TETH514_0172-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32786; Mature: 32786

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 83-83 ACT_SITE 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDKLITEGRNPDTLDIDRLSTEDMLKKINNEDKKVPIAVEKEIPNIAKAVDIIAEKLK
CCHHHHHHCCCCCCCCCHHCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHH
QGGRLIYIGAGTSGRLGILDASECPPTFGVDPEMVQGIIAGGDVAIRRSVEDAEDKEDLG
HCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHCC
KEDLKKKNLSSKDVVVGIAASGRTPYVLGALRYAKEVGAHTVGISCNPDSEMKKIVDIMI
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHH
APVVGPEVIMGSTRMKAGTAQKLVLNMLSTGAMIKLGKVYSNLMVDVKATNEKLINRAKR
HCCCCCHHEECCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHEEEEECHHHHHHHHHHH
IVKLATDADEKVIEKILKETNYNVKLTILMILTGLNQNKAKELLDRSNGYIAKALMLNEN
HHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCC
KS
CC
>Mature Secondary Structure
MDLDKLITEGRNPDTLDIDRLSTEDMLKKINNEDKKVPIAVEKEIPNIAKAVDIIAEKLK
CCHHHHHHCCCCCCCCCHHCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHH
QGGRLIYIGAGTSGRLGILDASECPPTFGVDPEMVQGIIAGGDVAIRRSVEDAEDKEDLG
HCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHCC
KEDLKKKNLSSKDVVVGIAASGRTPYVLGALRYAKEVGAHTVGISCNPDSEMKKIVDIMI
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHH
APVVGPEVIMGSTRMKAGTAQKLVLNMLSTGAMIKLGKVYSNLMVDVKATNEKLINRAKR
HCCCCCHHEECCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHEEEEECHHHHHHHHHHH
IVKLATDADEKVIEKILKETNYNVKLTILMILTGLNQNKAKELLDRSNGYIAKALMLNEN
HHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA