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The map label for this gene is hexR [C]

Identifier: 167038838

GI number: 167038838

Start: 170094

End: 170936

Strand: Direct

Name: hexR [C]

Synonym: Teth514_0168

Alternate gene names: 167038838

Gene position: 170094-170936 (Clockwise)

Preceding gene: 167038837

Following gene: 167038839

Centisome position: 6.92

GC content: 31.79

Gene sequence:

>843_bases
ATGCCAGGAGATATAGAGAAAATTAGGGCAGTTATTAATAATTTAAAACCATCAGAAAGAAAAATTGCTGAGTATATAAT
TGAAAATGCTGATAAGATTTCAGATTTATCTGTAGCTGAACTTGCAAAAAACAGCAATACCAGTGAAGCAAGTGTTGTGA
GATTTTGCAAAAGTCTCGGATACAAAGGATATCAAGATTTAAAAATAAAAATTGCTGCAGACTACACATATAAGACAAAA
AGTATTCAAGGTTTTGTTAATATAGATGATGATATTAATACCATAATTGTGAAAATATCTAAAAATAATATGGACTCAAT
AGAAAAAACAATGGATATGTTAGATAGAAACGAAGTAGAAAGAGCTGTTATTGCTATTTTAAATGCCAATAAAATAGACA
TTTATGGAGTTGGAGCATCTGCTATTGTTGCACAAGATATGTTGCAAAAATTTATGAGGATAAATAAATCTTGTACGGCA
TACAGTGATTCTCACATGCAACTTGCATCTGCGGCTAATCTTCGCCAAGGAGATGTGGCAATTGGTATTTCGTATTCAGG
TCAAACAGCAGATACTGTTGATGCTTTAAGGATAGCTAAAAATTCGGGCGCTACAACAATTTGTATAACAAGGTTTGGTA
ATTCACCTATAACAGAAGTTTCAGATATAAAACTTTTTGTATATTCTACTGAAGCAATCTTTAGAAGTGGTGCAATGGCA
TCAAGGATGGCACAACTTAATGTAGTAGATATATTGTTTTCTATAATAGCCTGCAGGAAATACGATGAGGTAATAAAATA
TTTAGAAAATACAAGTGAAGCGGTCTCATCAAGAAAATACTGA

Upstream 100 bases:

>100_bases
AAAACATTTTATGAAACCAAATTACAAAACCATAAAAAATACTTGAAATATTATTTCATAAGTAGTATAATATAAACTAG
AAAGGAGTGCAAACATTAAC

Downstream 100 bases:

>100_bases
AGGAGAGGTTTGTATGTTTAATATATTTAAAAAAAAGACTGATAAACTATTAATTAAAGCACCTGTTGATGGAGATGTGG
TAGAAATAGTAGATGTTCCA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPGDIEKIRAVINNLKPSERKIAEYIIENADKISDLSVAELAKNSNTSEASVVRFCKSLGYKGYQDLKIKIAADYTYKTK
SIQGFVNIDDDINTIIVKISKNNMDSIEKTMDMLDRNEVERAVIAILNANKIDIYGVGASAIVAQDMLQKFMRINKSCTA
YSDSHMQLASAANLRQGDVAIGISYSGQTADTVDALRIAKNSGATTICITRFGNSPITEVSDIKLFVYSTEAIFRSGAMA
SRMAQLNVVDILFSIIACRKYDEVIKYLENTSEAVSSRKY

Sequences:

>Translated_280_residues
MPGDIEKIRAVINNLKPSERKIAEYIIENADKISDLSVAELAKNSNTSEASVVRFCKSLGYKGYQDLKIKIAADYTYKTK
SIQGFVNIDDDINTIIVKISKNNMDSIEKTMDMLDRNEVERAVIAILNANKIDIYGVGASAIVAQDMLQKFMRINKSCTA
YSDSHMQLASAANLRQGDVAIGISYSGQTADTVDALRIAKNSGATTICITRFGNSPITEVSDIKLFVYSTEAIFRSGAMA
SRMAQLNVVDILFSIIACRKYDEVIKYLENTSEAVSSRKY
>Mature_279_residues
PGDIEKIRAVINNLKPSERKIAEYIIENADKISDLSVAELAKNSNTSEASVVRFCKSLGYKGYQDLKIKIAADYTYKTKS
IQGFVNIDDDINTIIVKISKNNMDSIEKTMDMLDRNEVERAVIAILNANKIDIYGVGASAIVAQDMLQKFMRINKSCTAY
SDSHMQLASAANLRQGDVAIGISYSGQTADTVDALRIAKNSGATTICITRFGNSPITEVSDIKLFVYSTEAIFRSGAMAS
RMAQLNVVDILFSIIACRKYDEVIKYLENTSEAVSSRKY

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=276, Percent_Identity=31.1594202898551, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788767, Length=276, Percent_Identity=29.7101449275362, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87082369, Length=239, Percent_Identity=27.1966527196653, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082130, Length=257, Percent_Identity=27.6264591439689, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30909; Mature: 30778

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDIEKIRAVINNLKPSERKIAEYIIENADKISDLSVAELAKNSNTSEASVVRFCKSLG
CCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHHCCCCCCHHHHHHHHHHCC
YKGYQDLKIKIAADYTYKTKSIQGFVNIDDDINTIIVKISKNNMDSIEKTMDMLDRNEVE
CCCCCCEEEEEEECCEEECCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
RAVIAILNANKIDIYGVGASAIVAQDMLQKFMRINKSCTAYSDSHMQLASAANLRQGDVA
HHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
IGISYSGQTADTVDALRIAKNSGATTICITRFGNSPITEVSDIKLFVYSTEAIFRSGAMA
EEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHHHHCCHHH
SRMAQLNVVDILFSIIACRKYDEVIKYLENTSEAVSSRKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PGDIEKIRAVINNLKPSERKIAEYIIENADKISDLSVAELAKNSNTSEASVVRFCKSLG
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHHCCCCCCHHHHHHHHHHCC
YKGYQDLKIKIAADYTYKTKSIQGFVNIDDDINTIIVKISKNNMDSIEKTMDMLDRNEVE
CCCCCCEEEEEEECCEEECCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
RAVIAILNANKIDIYGVGASAIVAQDMLQKFMRINKSCTAYSDSHMQLASAANLRQGDVA
HHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
IGISYSGQTADTVDALRIAKNSGATTICITRFGNSPITEVSDIKLFVYSTEAIFRSGAMA
EEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHHHHCCHHH
SRMAQLNVVDILFSIIACRKYDEVIKYLENTSEAVSSRKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]