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The map label for this gene is gatC [H]

Identifier: 167038796

GI number: 167038796

Start: 119096

End: 120475

Strand: Direct

Name: gatC [H]

Synonym: Teth514_0123

Alternate gene names: 167038796

Gene position: 119096-120475 (Clockwise)

Preceding gene: 167038795

Following gene: 167038797

Centisome position: 4.85

GC content: 35.87

Gene sequence:

>1380_bases
ATGTTTACGATGATTGTGAAAACCTTTGGGGCTGCTGTTCTACTTCCTATTGTAATACTAATTTTTGAATTAATTCTTGG
AGTAAAGTTTTCTAAAGCTCTCAGATCAGCACTTTACATAGGTGTAGGTCTTAATGGTTTAGTATCAGTCTTAAATCCGT
ATTTCATGGGATTAATTGGGAAAGCAGTTTCGGATATGATAACTACGGGAGGAGTGCATTTACCATATGTTGATACTGGT
TGGGCTCTTTTAGCAGCAGTGGGTTATTCAACACAAATTGGGGCACTGATTATTCCTATTGGTATAATTGTTAACATTAT
AATGCTTTTATTACACTGGACAGATACTTTAGACTTGGACGTATGGAATTTCTGGCATTGGGCTTTTATAGGCAGCATGG
TTTATTATGCGACTAATAATCTGGTATATGGGTTATTAACTGCGGTAGCAGTTGAAATGTTCCTTCTTATACTTGCCGAT
ATAACTGCTCCTACCATGCAAAAATTCTTTAATTTACCAGGGCTTGCTTTTCCGCATGCAAGTGGTCAAGGAGGAACATT
AATAGCTGTTCCTTTGAAATGGTTCTTTGATAAAATTGGATTAACCAAGATACAAATTAGTTCACGAACTATAAGAGAAA
AATTTGGTATTTTAGGAGATTCTGTTGTTGTGGGCTTTATAATAGCTACAATTATAGGGTTTATTGCATGGAGAAATAAA
TTAGGTGATATGCAAACTTGGTCTGGGATATTGGCATTAGGCATAGGAACAGGTGCTTTTATCTACTTATATCCCAAAGC
AACCGGAGCTCTCTTGGAAGGATTTGTACCTCTTAATGAGAGAGTAAGAGAGATACTTTCTAAGAGAGGCGTTAATAGAA
AATTAAATTTTGGGATGGATTCAGCTCTTACTATTGGACATCCGGATGTTCTTACTACAGGGCTTCTGACTATGTTGACT
ACTGTACCTCTTATATTTTTGCTACCAGGTAATAAATTTATCATGTTAGCAGATTTAGGAGTAACACCCTTTTTCTTAGC
TTCAGCTGTAACAGCAATAATGGGAGGAAATATTATTGCTTCTTATATCACTACAGTTATTGCTGTAATTATAACATTAT
ACTTTTCCAGTGCAGCATCTCCACTTTTTGCCCATATAGTAACTTTGATAGGAACCCAGTTACCTGATACTGGTAAAGCC
ATTGTTGGCGCTGATATGAGACCTTTACATGGATTGTTTTGGTTACTGGGGCAATCACCTATAGGACTTGTTGTAGCATT
TATAGGTATTTTTGCGATGCTATTTTTCTTTAAGAGAAGTCCTGAAGTATGGTATAAAGCATTTGGTTATAAAGGCAACG
AAAGCAAAGCAAAAATTTAA

Upstream 100 bases:

>100_bases
TTATTAGTGGAGTTCCGTTCTTAACTGGCATAGGAAAAGACCAAGTTTTTACTCAAATTCAAGATATTATTAACAATAAA
GAAAGAGGGGGTAAGTAAAA

Downstream 100 bases:

>100_bases
ACATATTATAATAAAATGCAATTAGTTGTACCAAACAAGAATAGTTGATAGTTTATTCTTGTTTGGTACTATAATTTGTT
GATGTGAATCATAATAATGA

Product: PTS system galactitol-specific IIC component

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MFTMIVKTFGAAVLLPIVILIFELILGVKFSKALRSALYIGVGLNGLVSVLNPYFMGLIGKAVSDMITTGGVHLPYVDTG
WALLAAVGYSTQIGALIIPIGIIVNIIMLLLHWTDTLDLDVWNFWHWAFIGSMVYYATNNLVYGLLTAVAVEMFLLILAD
ITAPTMQKFFNLPGLAFPHASGQGGTLIAVPLKWFFDKIGLTKIQISSRTIREKFGILGDSVVVGFIIATIIGFIAWRNK
LGDMQTWSGILALGIGTGAFIYLYPKATGALLEGFVPLNERVREILSKRGVNRKLNFGMDSALTIGHPDVLTTGLLTMLT
TVPLIFLLPGNKFIMLADLGVTPFFLASAVTAIMGGNIIASYITTVIAVIITLYFSSAASPLFAHIVTLIGTQLPDTGKA
IVGADMRPLHGLFWLLGQSPIGLVVAFIGIFAMLFFFKRSPEVWYKAFGYKGNESKAKI

Sequences:

>Translated_459_residues
MFTMIVKTFGAAVLLPIVILIFELILGVKFSKALRSALYIGVGLNGLVSVLNPYFMGLIGKAVSDMITTGGVHLPYVDTG
WALLAAVGYSTQIGALIIPIGIIVNIIMLLLHWTDTLDLDVWNFWHWAFIGSMVYYATNNLVYGLLTAVAVEMFLLILAD
ITAPTMQKFFNLPGLAFPHASGQGGTLIAVPLKWFFDKIGLTKIQISSRTIREKFGILGDSVVVGFIIATIIGFIAWRNK
LGDMQTWSGILALGIGTGAFIYLYPKATGALLEGFVPLNERVREILSKRGVNRKLNFGMDSALTIGHPDVLTTGLLTMLT
TVPLIFLLPGNKFIMLADLGVTPFFLASAVTAIMGGNIIASYITTVIAVIITLYFSSAASPLFAHIVTLIGTQLPDTGKA
IVGADMRPLHGLFWLLGQSPIGLVVAFIGIFAMLFFFKRSPEVWYKAFGYKGNESKAKI
>Mature_459_residues
MFTMIVKTFGAAVLLPIVILIFELILGVKFSKALRSALYIGVGLNGLVSVLNPYFMGLIGKAVSDMITTGGVHLPYVDTG
WALLAAVGYSTQIGALIIPIGIIVNIIMLLLHWTDTLDLDVWNFWHWAFIGSMVYYATNNLVYGLLTAVAVEMFLLILAD
ITAPTMQKFFNLPGLAFPHASGQGGTLIAVPLKWFFDKIGLTKIQISSRTIREKFGILGDSVVVGFIIATIIGFIAWRNK
LGDMQTWSGILALGIGTGAFIYLYPKATGALLEGFVPLNERVREILSKRGVNRKLNFGMDSALTIGHPDVLTTGLLTMLT
TVPLIFLLPGNKFIMLADLGVTPFFLASAVTAIMGGNIIASYITTVIAVIITLYFSSAASPLFAHIVTLIGTQLPDTGKA
IVGADMRPLHGLFWLLGQSPIGLVVAFIGIFAMLFFFKRSPEVWYKAFGYKGNESKAKI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=381, Percent_Identity=32.5459317585302, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1790758, Length=389, Percent_Identity=31.3624678663239, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 49752; Mature: 49752

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTMIVKTFGAAVLLPIVILIFELILGVKFSKALRSALYIGVGLNGLVSVLNPYFMGLIG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KAVSDMITTGGVHLPYVDTGWALLAAVGYSTQIGALIIPIGIIVNIIMLLLHWTDTLDLD
HHHHHHHHCCCEECCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VWNFWHWAFIGSMVYYATNNLVYGLLTAVAVEMFLLILADITAPTMQKFFNLPGLAFPHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
SGQGGTLIAVPLKWFFDKIGLTKIQISSRTIREKFGILGDSVVVGFIIATIIGFIAWRNK
CCCCCEEEEEEHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LGDMQTWSGILALGIGTGAFIYLYPKATGALLEGFVPLNERVREILSKRGVNRKLNFGMD
CCCHHHHHHHHHEEECCCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCCCC
SALTIGHPDVLTTGLLTMLTTVPLIFLLPGNKFIMLADLGVTPFFLASAVTAIMGGNIIA
CCEECCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCHHHH
SYITTVIAVIITLYFSSAASPLFAHIVTLIGTQLPDTGKAIVGADMRPLHGLFWLLGQSP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCH
IGLVVAFIGIFAMLFFFKRSPEVWYKAFGYKGNESKAKI
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFTMIVKTFGAAVLLPIVILIFELILGVKFSKALRSALYIGVGLNGLVSVLNPYFMGLIG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KAVSDMITTGGVHLPYVDTGWALLAAVGYSTQIGALIIPIGIIVNIIMLLLHWTDTLDLD
HHHHHHHHCCCEECCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VWNFWHWAFIGSMVYYATNNLVYGLLTAVAVEMFLLILADITAPTMQKFFNLPGLAFPHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
SGQGGTLIAVPLKWFFDKIGLTKIQISSRTIREKFGILGDSVVVGFIIATIIGFIAWRNK
CCCCCEEEEEEHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LGDMQTWSGILALGIGTGAFIYLYPKATGALLEGFVPLNERVREILSKRGVNRKLNFGMD
CCCHHHHHHHHHEEECCCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCCCC
SALTIGHPDVLTTGLLTMLTTVPLIFLLPGNKFIMLADLGVTPFFLASAVTAIMGGNIIA
CCEECCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCHHHH
SYITTVIAVIITLYFSSAASPLFAHIVTLIGTQLPDTGKAIVGADMRPLHGLFWLLGQSP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCH
IGLVVAFIGIFAMLFFFKRSPEVWYKAFGYKGNESKAKI
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]