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The map label for this gene is y4uB

Identifier: 16519967

GI number: 16519967

Start: 169066

End: 170469

Strand: Reverse

Name: y4uB

Synonym: NGR_a01380

Alternate gene names: 16519967

Gene position: 170469-169066 (Counterclockwise)

Preceding gene: 16519966

Following gene: 16519968

Centisome position: 31.79

GC content: 60.61

Gene sequence:

>1404_bases
ATGACCATCGATATTAAGGACATCAGCGAGAAGGACCGCAATACGGTCCTGCATCCGTTCACACAGCTGAAGGACTTTGC
GACCGGAAAGCTTCGTGAGCCGACGATCGTCGAGACGGGCAAGGGGATCCGCATCCAGGACGCGCGTGGTAACCAGCTGA
TCGACGGCTTTGCCGGCCTCTATTGCGTCAATGTCGGCTACGGCCGCACCGAAGTCGCGGAGGCGATCTCACGCCAGGCC
TATCGCCTTGCCTATTATCATTCATATGCGGCACACACGACGGATGAACTCGCAATTCTGTCGGATCGCCTCGTGAAGAT
GGCCCCGGGCAAGATGAGCAAGGTGTTTTACGGCATGTCCGGTTCGGACGCCAATGAGACCCAGGCCAAGCTCGTCTGGT
ACTACAACAATCTGCGTGGCAAGCCGACGAAGAAGAAGATTATCTCGCGCGAACGCGGCTATCATGGCTGCAGCGTCGTC
TCCGGCTCGATGACCGGCATGAGCTTCTATCACGATCACATGGACCTGCCGCTGCCGCAGATCTGCCACACCGGCGTGCC
GCACCATTATTGGGGTGCAAACCCGGGCGAGACGGAACGCGAGTTCTCCGCCCGTCGCGCCGCCGAGCTCGACGAGATGA
TCGAAACACTGGGTCCCGATAATGTCGGCGCCTTTATCGCCGAGCCTGTGCTTGGTACCGGCGGTATCACGCCGCCGCCG
GAAGGCTATTGGGAAGCGATCCAGGCCGTGTTGAAGAAGCACGACGTGCTGCTGATCGCCGACGAAGTCATCACCGGCTT
CGGCCGCACCGGCTCCATGTTTGGCTCGCAGCATTACGGCATCGAGCCTGACCTGATCACCGTCGCCAAGGGTCTGACCT
CGGCCTACTTCCCGCTCTCAGCCTCAATCGTCGGCGAGAAGGTCTACAAGGTGCTGGAAGACGGCGCCGATCGCGTCGGC
GCCTTCTCCCATGGCTATACCTATTCCGGTCATCCCATTGGGGCGGCCGCAGCAAATGCGGTGCTCGACATCGTCGAAAA
GGAAGATTTGCCGGGCAATGCCCGTGAGGTCGGCGGCTATTTCCAGGCGCAGCTCAAGGAGAAGTTCGCCCAGCTGCCGA
TCGTCGGCGAAGTGCGCGGTGTCGGCCTGATGGGCGCCATCGAGTTCGTTGGCGATCGTGAGAACAAGAAGCGTTTCGAC
CCATTGCTGAAGGTCGGAGCTCGTGTCTCCAAAGCTGCCCGCGATCGCGGCCTTATTGCCCGCGCCATGCCGCATGGCGA
CATTCTCGGCTTTGCGCCGCCGCTCGTCACCACCAAAGAGGAAGTCGATGAGATCGTCGCCATGGCCGAGAAGGCCGTTC
GCTCTGTCATGGATGAGTTGGTCCGCGACGGTCAGAAGCTCTGA

Upstream 100 bases:

>100_bases
ATTTCATGGTCACGTACATTTTAGGTCGAAACAAGCGCGTTCGAGCGCCTGACAACAGGAACTCATCGCCAAATCCTTCG
CAGCCCGAGAGGAAGCATTT

Downstream 100 bases:

>100_bases
GCGATAGTTAAGCCTTCGGCGGCGGTGGATGCCGGCCGCCGAAGGCTTGTGATCAACGACTGCATGAAGCCGGAAAGGGG
CAGGAGATCACCTTTGCCTC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGLYCVNVGYGRTEVAEAISRQA
YRLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMSGSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVV
SGSMTGMSFYHDHMDLPLPQICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPP
EGYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLSASIVGEKVYKVLEDGADRVG
AFSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGYFQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFD
PLLKVGARVSKAARDRGLIARAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL

Sequences:

>Translated_467_residues
MTIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGLYCVNVGYGRTEVAEAISRQA
YRLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMSGSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVV
SGSMTGMSFYHDHMDLPLPQICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPP
EGYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLSASIVGEKVYKVLEDGADRVG
AFSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGYFQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFD
PLLKVGARVSKAARDRGLIARAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL
>Mature_466_residues
TIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGLYCVNVGYGRTEVAEAISRQAY
RLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMSGSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVVS
GSMTGMSFYHDHMDLPLPQICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPPE
GYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLSASIVGEKVYKVLEDGADRVGA
FSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGYFQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFDP
LLKVGARVSKAARDRGLIARAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI13994255, Length=457, Percent_Identity=28.2275711159737, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI4557809, Length=426, Percent_Identity=28.6384976525822, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=28, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=27.7251184834123, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI226442709, Length=373, Percent_Identity=28.9544235924933, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI284507298, Length=237, Percent_Identity=33.7552742616034, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI24119277, Length=442, Percent_Identity=25.3393665158371, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI145693181, Length=412, Percent_Identity=31.7961165048544, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI1788044, Length=426, Percent_Identity=28.4037558685446, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1789759, Length=418, Percent_Identity=27.7511961722488, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789016, Length=416, Percent_Identity=28.125, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787560, Length=431, Percent_Identity=26.9141531322506, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786991, Length=454, Percent_Identity=26.6519823788546, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786349, Length=421, Percent_Identity=26.3657957244656, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32564660, Length=450, Percent_Identity=28.4444444444444, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=431, Percent_Identity=27.6102088167053, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=31.9548872180451, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=26.1467889908257, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=450, Percent_Identity=22.8888888888889, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=435, Percent_Identity=29.1954022988506, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324432, Length=434, Percent_Identity=29.4930875576037, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324386, Length=490, Percent_Identity=27.3469387755102, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321456, Length=357, Percent_Identity=24.9299719887955, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI161085790, Length=457, Percent_Identity=30.4157549234136, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI28574759, Length=453, Percent_Identity=30.0220750551876, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21357415, Length=430, Percent_Identity=28.1395348837209, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356575, Length=439, Percent_Identity=26.879271070615, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281366494, Length=396, Percent_Identity=22.4747474747475, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667139, Length=396, Percent_Identity=22.4747474747475, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667143, Length=396, Percent_Identity=22.4747474747475, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4UB_RHISN (Q53196)

Other databases:

- EMBL:   Z68203
- EMBL:   U00090
- RefSeq:   NP_444087.1
- ProteinModelPortal:   Q53196
- SMR:   Q53196
- GeneID:   962455
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a01380
- HOGENOM:   HBG725944
- ProtClustDB:   PRK07482
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 51006; Mature: 50875

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGL
CEECCCCCCCCCCCCEECHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCHHHHHHHCE
YCVNVGYGRTEVAEAISRQAYRLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCC
GSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVVSGSMTGMSFYHDHMDLPLPQ
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHCCCCCHHH
ICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
EGYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLS
CHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH
ASIVGEKVYKVLEDGADRVGAFSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGY
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
FQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFDPLLKVGARVSKAARDRGLIA
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
RAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGL
EECCCCCCCCCCCCEECHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCHHHHHHHCE
YCVNVGYGRTEVAEAISRQAYRLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCC
GSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVVSGSMTGMSFYHDHMDLPLPQ
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHCCCCCHHH
ICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
EGYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLS
CHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH
ASIVGEKVYKVLEDGADRVGAFSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGY
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
FQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFDPLLKVGARVSKAARDRGLIA
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
RAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424