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The map label for this gene is ackA [H]

Identifier: 16273124

GI number: 16273124

Start: 1270934

End: 1272139

Strand: Reverse

Name: ackA [H]

Synonym: HI1204

Alternate gene names: 16273124

Gene position: 1272139-1270934 (Counterclockwise)

Preceding gene: 16273128

Following gene: 16273123

Centisome position: 69.51

GC content: 39.88

Gene sequence:

>1206_bases
ATGTCAAAACTTGTTCTTATCCTTAACTGTGGTAGTTCTTCACTCAAATTTGCAATTCTTGATCCAGCAACAGGGGAAGA
AAAATTATCTGGCTTAGCCGAAGCATTTTTCTTACCAGAAGCACGTATCAAATGGAAACTCAATGGAGAGAAAGGTAACG
CAGATTTAGGCGCAGGCGCAGCGCATACTGAAGCACTTAATTTTATCGCATCTAACATTCTGAATGATGAGCTTAAAAAT
TCTATCGCGGCAATTGGTCATCGTATCGTTCACGGTGGCGAAAAATACACTCAATCTGTCATCGTAACAGATGAAGTTGT
TAAAGGAATTGAAGATGCTGCACAATTTGCGCCACTTCACAACCCTGCTCACTTAATTGGTATTCGCGAAGCATTCAAGG
CATTCCCACACTTAAAAGATAAAAACGTGGTAGTTTTTGATACAGCATTCCACCAAACTATGCCTGAAGAAGCCTTCCTT
TATGCCCTTCCATACTCTTTATATAAAGAACACGGCGTACGTCGCTATGGTGCACACGGCACAAGTCACTACTTCGTTTC
TCGTGAAGTCGCTAAATATGTAGGCAAACCTGCAGATCAAGTAAATGCTATTATTTGTCACTTAGGTAATGGTGGTTCTG
TTTCTGTTGTGCGTAACGGTCAATGTATTGATACTTCAATGGGCTTAACTCCGCTAGAAGGTTTAGTAATGGGTACGCGT
TGTGGCGATATTGACCCTGCAATCGTATTCTACCTATACAAAACACTAGGTATGTCTATGGATCAAATCGAAGAGACTTT
AGTGAAAAAATCGGGTCTTTTAGGTTTAACTGAAGTAACAAGCGACTGCCGTTATGCTGAAGATAACTACGATGATGAAT
CTAAACCAGAAACAAGACGTGCTTTAAATGTTTATAGCTATCGTTTAGCGAAATACATTGGTGCTTATATGGCTGTGTTG
GGCGATGATCACTTAGATGCAATTGCATTCACTGGTGGTATTGGCGAAAACTCAGCGCACGTTCGTGAATTAGCCTTAAA
TCACTTAAAATTATTCGGCATTAAAATCGATAACGAACGAAATCTTGCCACACGTTTTGGTAAAGATGGTGTAATCACCA
CTGATGATTCCGCATTTAAAGCAATTGTTCTTCCAACTAACGAAGAATTGGTTATCGCACAAGATACCGCAAAACTTTGT
TTCTAA

Upstream 100 bases:

>100_bases
TGAATTTATTTTATTCATCAAAAGGTGTATTCTATGTCTGATTTTTCAAACCATCTTAGATGATGGATTTCTATTAACCT
CAATCAAATATAGGGTTCCT

Downstream 100 bases:

>100_bases
TTTAACAACAAGCTGCCGAATTTTTCGGCAGTTTTTATTTATAAAATATACATATTAAGGTTTAACTATGTCTCGCACGA
TTATTCTTATCCCTGTAAGT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILNDELKN
SIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFL
YALPYSLYKEHGVRRYGAHGTSHYFVSREVAKYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTR
CGDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETRRALNVYSYRLAKYIGAYMAVL
GDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNERNLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLC
F

Sequences:

>Translated_401_residues
MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILNDELKN
SIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFL
YALPYSLYKEHGVRRYGAHGTSHYFVSREVAKYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTR
CGDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETRRALNVYSYRLAKYIGAYMAVL
GDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNERNLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLC
F
>Mature_400_residues
SKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILNDELKNS
IAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFLY
ALPYSLYKEHGVRRYGAHGTSHYFVSREVAKYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTRC
GDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETRRALNVYSYRLAKYIGAYMAVLG
DDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNERNLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLCF

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=68.75, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=42.1717171717172, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43758; Mature: 43627

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGA
CCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
AHTEALNFIASNILNDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHHHHHHCCCC
NPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFLYALPYSLYKEHGVRRYGAHG
CCHHHHHHHHHHHHCCCCCCCCEEEEECHHHHCCCCCCEEEECCHHHHHHCCCEECCCCC
TSHYFVSREVAKYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTR
CCCHHHHHHHHHHHCCCHHHCCEEEEECCCCCEEEEEECCEEEECCCCCCCHHHEEEECC
CGDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETRR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCCHHHH
ALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNER
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHEEEEEEEECCCC
NLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLCF
CHHHHCCCCCCEECCCCCEEEEEECCCCCEEEEECCHHHCC
>Mature Secondary Structure 
SKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGA
CCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
AHTEALNFIASNILNDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHHHHHHCCCC
NPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFLYALPYSLYKEHGVRRYGAHG
CCHHHHHHHHHHHHCCCCCCCCEEEEECHHHHCCCCCCEEEECCHHHHHHCCCEECCCCC
TSHYFVSREVAKYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTR
CCCHHHHHHHHHHHCCCHHHCCEEEEECCCCCEEEEEECCEEEECCCCCCCHHHEEEECC
CGDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETRR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCCHHHH
ALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNER
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHEEEEEEEECCCC
NLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLCF
CHHHHCCCCCCEECCCCCEEEEEECCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA