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The map label for this gene is suhB [H]

Identifier: 162419350

GI number: 162419350

Start: 460396

End: 461199

Strand: Direct

Name: suhB [H]

Synonym: YpAngola_A0438

Alternate gene names: 162419350

Gene position: 460396-461199 (Clockwise)

Preceding gene: 162420670

Following gene: 162418375

Centisome position: 10.22

GC content: 49.5

Gene sequence:

>804_bases
ATGCATCCGATGCTGACTATCGCCATACGCGCTGCGCGTAAGGCCGGTAACCTGATTGCCAAAAATTATGAAACCCCGGA
CGCTGTCGAAGCGAGCCAGAAAGGCAGTAATGACTTTGTTACTAACGTTGACCGCGATGCAGAGCATCTGATCATTGACG
TTATCCGTAAATCTTACCCAAAACACACTATTATTAGTGAAGAATGCGGTGAGTTGGTCGGCGAAGATGATGATGTACAA
TGGGTTATTGATCCACTGGATGGCACTACCAACTTCATCAAACGCCTCCCTCACTTTGCAGTCTCTATTGCCGTGCGCAT
TAAAGGCCGGACAGAAGTCGCCGTGGTTTACGATCCAATGCGTAACGAACTGTTCACCGCCAGCCGTGGTCAAGGCGCCC
AGTTAAATGGTTATCGTCTGCGTGGTACCAACGCTAAAGATTTAGATGGCACTATTCTGGCTACCGGTTTCCCATTCAAA
GTGAAGCAACACGCCCCTGCTTATATTCGCGTCGTCGGTAAGCTATTTGAGCAGTGTGCAGATTTCCGTCGCACCGGTTC
AGCCGCATTGGATCTGGCTTATGTCGCAGCAGGCCGTGTTGATGGCTTCTTTGAGATTGGGTTGAAACCGTGGGATTTCG
CAGGTGGCGAGCTATTGGTTCGTGAGTCTGGTGGTATCGTGACTGACTTTGCCGGCGGCCATAACCATTTCAGCTCTGGC
AATATCGTGGCCGGTAATCCACGTATTGTTAAATCTATCGTTCAAGCCATGAGCAACGAAATCAGTGATGCGTTAAAGCG
TTAA

Upstream 100 bases:

>100_bases
GGATAATCGCCATATCTTAACACAGACATAGGCATTTATCAGATCCCCTGCTATACTGTGCGCCGTTTCTCGTTCTTTAA
CATCCTAGTGGAAGATACCC

Downstream 100 bases:

>100_bases
TTCCACGCAAATAGCCGTTTCAGATAAAAAGCCAGTCAGGGTTAGCCGACTGGCTTTTTTTATTGGGAACCCCTCTGCAG
CGTCAAGGTCGAAGGGTATC

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHPMLTIAIRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDRDAEHLIIDVIRKSYPKHTIISEECGELVGEDDDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTASRGQGAQLNGYRLRGTNAKDLDGTILATGFPFK
VKQHAPAYIRVVGKLFEQCADFRRTGSAALDLAYVAAGRVDGFFEIGLKPWDFAGGELLVRESGGIVTDFAGGHNHFSSG
NIVAGNPRIVKSIVQAMSNEISDALKR

Sequences:

>Translated_267_residues
MHPMLTIAIRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDRDAEHLIIDVIRKSYPKHTIISEECGELVGEDDDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTASRGQGAQLNGYRLRGTNAKDLDGTILATGFPFK
VKQHAPAYIRVVGKLFEQCADFRRTGSAALDLAYVAAGRVDGFFEIGLKPWDFAGGELLVRESGGIVTDFAGGHNHFSSG
NIVAGNPRIVKSIVQAMSNEISDALKR
>Mature_267_residues
MHPMLTIAIRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDRDAEHLIIDVIRKSYPKHTIISEECGELVGEDDDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTASRGQGAQLNGYRLRGTNAKDLDGTILATGFPFK
VKQHAPAYIRVVGKLFEQCADFRRTGSAALDLAYVAAGRVDGFFEIGLKPWDFAGGELLVRESGGIVTDFAGGHNHFSSG
NIVAGNPRIVKSIVQAMSNEISDALKR

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=251, Percent_Identity=33.4661354581673, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI221625487, Length=251, Percent_Identity=33.4661354581673, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI7657236, Length=258, Percent_Identity=32.9457364341085, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI221625507, Length=137, Percent_Identity=36.4963503649635, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=83.8951310861423, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1790659, Length=207, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=233, Percent_Identity=33.0472103004292, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193202570, Length=234, Percent_Identity=31.1965811965812, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6321836, Length=234, Percent_Identity=30.3418803418803, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320493, Length=201, Percent_Identity=30.8457711442786, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357329, Length=266, Percent_Identity=34.9624060150376, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24664926, Length=260, Percent_Identity=30.7692307692308, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357303, Length=240, Percent_Identity=34.1666666666667, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24664922, Length=256, Percent_Identity=30.078125, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21357957, Length=266, Percent_Identity=31.9548872180451, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24664918, Length=235, Percent_Identity=35.3191489361702, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29155; Mature: 29155

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLTIAIRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDRDAEHLIIDVIRKSYP
CCCCEEHHHHHHHHHCCEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
KHTIISEECGELVGEDDDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPM
CCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEEEECCCEEEEEEECCC
RNELFTASRGQGAQLNGYRLRGTNAKDLDGTILATGFPFKVKQHAPAYIRVVGKLFEQCA
CCCEEECCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHH
DFRRTGSAALDLAYVAAGRVDGFFEIGLKPWDFAGGELLVRESGGIVTDFAGGHNHFSSG
HHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCC
NIVAGNPRIVKSIVQAMSNEISDALKR
CEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPMLTIAIRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDRDAEHLIIDVIRKSYP
CCCCEEHHHHHHHHHCCEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
KHTIISEECGELVGEDDDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPM
CCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEEEECCCEEEEEEECCC
RNELFTASRGQGAQLNGYRLRGTNAKDLDGTILATGFPFKVKQHAPAYIRVVGKLFEQCA
CCCEEECCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHH
DFRRTGSAALDLAYVAAGRVDGFFEIGLKPWDFAGGELLVRESGGIVTDFAGGHNHFSSG
HHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCC
NIVAGNPRIVKSIVQAMSNEISDALKR
CEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]