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The map label for this gene is cirA [H]

Identifier: 162149477

GI number: 162149477

Start: 3792478

End: 3795135

Strand: Direct

Name: cirA [H]

Synonym: GDI_3715

Alternate gene names: 162149477

Gene position: 3792478-3795135 (Clockwise)

Preceding gene: 162149476

Following gene: 162149478

Centisome position: 96.15

GC content: 65.69

Gene sequence:

>2658_bases
ATGACCCTGAGGCGAAGCCTTATCGCGGCCACGATTTTAGCAATGCAGTTTGACCTGTCGGCGGCCCTGGCCCAGACAGC
GCCATCCCAGACGGCAACGCCCCAAAAACCCGCTACCTCCGGTCATCGCCATGTCGCGAAGGCCGGGAAGAAGGCCGGCG
CCCCCAAGGCGCATGCCGCGACGGCTTCGGCCGCGACGCCGGGCGTGGTGCCGGCTGCCGCGGTATCGACCGCCGCCGTG
GCGCCCGTGGTCCCGGTCGCGCCCGTCTATCATGCGCCGCCGCCGGATGCCGGCGAGGCGGTGATCGTCACCGGCACCCA
CGCCTATAACCGGCATGCCCGCGATTCCACGGCGCCGATCACGGTCATTTCCGCCGCCACCCTGCAACGGACCGGCGCGG
TCAACCTCGCCGACGCGCTGACGCGCATGGACCCGTCGATCACCGAGCAGACGATGGGCGCCGACGCGGGCGCGCTGACC
TCGTCCATCCGCATGCGCGGCCTGAACCCGAACGAAGTGCTGGTCCTGGTGGATGGCAAGCGCCGCCACACCACGGCCAA
CATCTATGCCGACCAGGGGCCGCAGCAGGGTTCGACGCCGGTCGACCTGAACATGCTGCCGGCGAATGCGATCGACCATA
TCGAAATCCTGCGTGACGGCGCGGCGGCCATGTACGGCTCGGACGCCATCGCGGGCGTGGTCAACATCATCACGAAGAAG
ACGGCGCACGGGCTGAACCTGACCGGGCAGACCGGGGCCAATGCCTATAACGGCGACGGCTGGCAGTACCAGACCGGTAT
CGATGGCGGCTTCAGCTTCCTGGGCGATGGCTATGTCCATATTTCCGGACAGGTCGAGCATGCCGACCACATGGTGCCGA
AGGGCGCGTCCGACCTGCGTACGGACCCGAACAACGCGGATTACGGGGGGGTGAACTTCCCTAGCAATTCGAACATGATC
ATGAGCACGCCGGAGGAGACGCGCGAAAACCTGCTGATCAATTTCGGCAAGACGGTGACCGAGGGCATCGATTTCTACGG
CCAGATCACCTACGCCCATCGCCACAGCGAGGCGTACGAGAACTACCGCACGCCGACGAAGGCGCCGCAGATCTATCCGG
CCGGCTTCTCGCCGCTCGAGACGATCGACGAAAACGACTTCGCCGCGACGCTGGGCCTGAAGGGCGACAATTTCCTGGGC
TTCGACTGGGATGTCAGCACGACCTACGGCCAGGATGACGATACGATCGGCAACAAGAACACCGCCAATCCGAACATGCT
GAGCACCGACCCCACGGTGTGCGGCACGAACCCGGCGAACGCGGCCACCTATTCGACGGACGGCTGCGGCTGGTCGCCGA
CCACGGTGCTGGCCGAGCGGTATTCGCTGGCGCAATGGACGAACAACGCGGATTTCCGCCGTCGCCTGAAGATTGCCAAC
GTCGTGCCGGTGACGGTGGCCTTCGGCGCCGAGCATCGTCTGGAACAGTACCAGATCTGGCCGGGCAATCCGCCGTCCTA
CCAGATCGGCGGCACGCAGGGTTATGCCGGCCTGATGCCGGAAAACGCGGGCAAGTGGGGCCGTGACATCTGGGCCGGCT
ACCTGGACGGCGACTTCCACCTGCTGCCGCACTGGGACCTGGATTTCGCGGGCCGGTTCGAGCACTACACCGATTTCGGC
AACACCGAGAACGGCAAGGTCTCGACGCGCTACGATTTCACCAAGCGCATCGCCATCCGTGGCACGGTCAGCAACGGCTT
CCGCGCGCCGACCCTGCCGGAAGAACATTTCAGCGCCCTGAACGTGTCGCCCACCGGCGCCACGGGCCTGCTGTCGACCA
CCAGCGCCGCGGGCCAGTCGGTCGGCGCGCTGCCGCTGAAGCCGGAGCGCTCGTTCAGCGCCGAGGCCGGCCTGGTGCTG
GAGCCGGTCGACGGCTGGCACGTGTCGGCCGACGTCTACCAGATCAACATCCGCGACCGCATTTTCGGCAGCTCGACCTT
CAGTGACAGCGATGCGCTGAATGCGATCGCCATGACCGGTGCCTCGCTGCCGGCCGGCATCACCAATTCCGACGTGTTCG
TGAACTACTTCGCCAATGTCGGCAGCACGAAGACGCAGGGCCTGGACATCATGTCCGACTACCTGCTGCGCCTGAACCAG
TACGGCAACGTGGACCTGAGCCTGGGCGTCAACCTGAACCGCACGAAGGTGACCCGCACCAACACCCTGGCCAACGGCCT
GCCGGCGCTGAACGCGCAGACCGCGTCCTACCTGACCAACGGCGCGCCGAAGAACAAGATCGTCCTGCAGGCGCACTGGA
CCATCGGCCAGTGGGACGTCAACGTCCGCCAGACCCGCTATGGCGCGACCACGATCCTGCAGACCTACGAGGACCAGGCC
CCGGCGGCGCTGCAGTACTCGAACACCCAGTGGCTGTCGTTCAAGAACACCGCCGCGTGGATGACCGACCTGGAAGTGGG
CTATCGCCTGAACCACATCTGGCACTTCGCCGTGGGTGCGAACAACATCTTCAACGTCCGCCCGCGCCGCCTGCCGCTGA
TCGCCAACTACCTGGGCGCCAACCAGTTCGACCAGAACTCGTCCGGCATCCCCTTCACCGGCGGCTACTACTACGGCCGG
ATCAACGCATCGTTTTGA

Upstream 100 bases:

>100_bases
GGAATCGATACGAGTGATTCCAGTTTCGTATTGAAGCGCCGGTTGGATTCGGTTCCACTGGGAGTGTTAAATAATAACGT
ATGCAGGAGCGGTTGAGTCT

Downstream 100 bases:

>100_bases
CCCGGTTTTTCCAGTCCGACGCTTCGGGGCCCGCGGTTGCATTGCAACCGCGGGTTTCGTCGTTCTGGGACGCATGACGC
AACGGTATGACCGCATGCGG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 885; Mature: 884

Protein sequence:

>885_residues
MTLRRSLIAATILAMQFDLSAALAQTAPSQTATPQKPATSGHRHVAKAGKKAGAPKAHAATASAATPGVVPAAAVSTAAV
APVVPVAPVYHAPPPDAGEAVIVTGTHAYNRHARDSTAPITVISAATLQRTGAVNLADALTRMDPSITEQTMGADAGALT
SSIRMRGLNPNEVLVLVDGKRRHTTANIYADQGPQQGSTPVDLNMLPANAIDHIEILRDGAAAMYGSDAIAGVVNIITKK
TAHGLNLTGQTGANAYNGDGWQYQTGIDGGFSFLGDGYVHISGQVEHADHMVPKGASDLRTDPNNADYGGVNFPSNSNMI
MSTPEETRENLLINFGKTVTEGIDFYGQITYAHRHSEAYENYRTPTKAPQIYPAGFSPLETIDENDFAATLGLKGDNFLG
FDWDVSTTYGQDDDTIGNKNTANPNMLSTDPTVCGTNPANAATYSTDGCGWSPTTVLAERYSLAQWTNNADFRRRLKIAN
VVPVTVAFGAEHRLEQYQIWPGNPPSYQIGGTQGYAGLMPENAGKWGRDIWAGYLDGDFHLLPHWDLDFAGRFEHYTDFG
NTENGKVSTRYDFTKRIAIRGTVSNGFRAPTLPEEHFSALNVSPTGATGLLSTTSAAGQSVGALPLKPERSFSAEAGLVL
EPVDGWHVSADVYQINIRDRIFGSSTFSDSDALNAIAMTGASLPAGITNSDVFVNYFANVGSTKTQGLDIMSDYLLRLNQ
YGNVDLSLGVNLNRTKVTRTNTLANGLPALNAQTASYLTNGAPKNKIVLQAHWTIGQWDVNVRQTRYGATTILQTYEDQA
PAALQYSNTQWLSFKNTAAWMTDLEVGYRLNHIWHFAVGANNIFNVRPRRLPLIANYLGANQFDQNSSGIPFTGGYYYGR
INASF

Sequences:

>Translated_885_residues
MTLRRSLIAATILAMQFDLSAALAQTAPSQTATPQKPATSGHRHVAKAGKKAGAPKAHAATASAATPGVVPAAAVSTAAV
APVVPVAPVYHAPPPDAGEAVIVTGTHAYNRHARDSTAPITVISAATLQRTGAVNLADALTRMDPSITEQTMGADAGALT
SSIRMRGLNPNEVLVLVDGKRRHTTANIYADQGPQQGSTPVDLNMLPANAIDHIEILRDGAAAMYGSDAIAGVVNIITKK
TAHGLNLTGQTGANAYNGDGWQYQTGIDGGFSFLGDGYVHISGQVEHADHMVPKGASDLRTDPNNADYGGVNFPSNSNMI
MSTPEETRENLLINFGKTVTEGIDFYGQITYAHRHSEAYENYRTPTKAPQIYPAGFSPLETIDENDFAATLGLKGDNFLG
FDWDVSTTYGQDDDTIGNKNTANPNMLSTDPTVCGTNPANAATYSTDGCGWSPTTVLAERYSLAQWTNNADFRRRLKIAN
VVPVTVAFGAEHRLEQYQIWPGNPPSYQIGGTQGYAGLMPENAGKWGRDIWAGYLDGDFHLLPHWDLDFAGRFEHYTDFG
NTENGKVSTRYDFTKRIAIRGTVSNGFRAPTLPEEHFSALNVSPTGATGLLSTTSAAGQSVGALPLKPERSFSAEAGLVL
EPVDGWHVSADVYQINIRDRIFGSSTFSDSDALNAIAMTGASLPAGITNSDVFVNYFANVGSTKTQGLDIMSDYLLRLNQ
YGNVDLSLGVNLNRTKVTRTNTLANGLPALNAQTASYLTNGAPKNKIVLQAHWTIGQWDVNVRQTRYGATTILQTYEDQA
PAALQYSNTQWLSFKNTAAWMTDLEVGYRLNHIWHFAVGANNIFNVRPRRLPLIANYLGANQFDQNSSGIPFTGGYYYGR
INASF
>Mature_884_residues
TLRRSLIAATILAMQFDLSAALAQTAPSQTATPQKPATSGHRHVAKAGKKAGAPKAHAATASAATPGVVPAAAVSTAAVA
PVVPVAPVYHAPPPDAGEAVIVTGTHAYNRHARDSTAPITVISAATLQRTGAVNLADALTRMDPSITEQTMGADAGALTS
SIRMRGLNPNEVLVLVDGKRRHTTANIYADQGPQQGSTPVDLNMLPANAIDHIEILRDGAAAMYGSDAIAGVVNIITKKT
AHGLNLTGQTGANAYNGDGWQYQTGIDGGFSFLGDGYVHISGQVEHADHMVPKGASDLRTDPNNADYGGVNFPSNSNMIM
STPEETRENLLINFGKTVTEGIDFYGQITYAHRHSEAYENYRTPTKAPQIYPAGFSPLETIDENDFAATLGLKGDNFLGF
DWDVSTTYGQDDDTIGNKNTANPNMLSTDPTVCGTNPANAATYSTDGCGWSPTTVLAERYSLAQWTNNADFRRRLKIANV
VPVTVAFGAEHRLEQYQIWPGNPPSYQIGGTQGYAGLMPENAGKWGRDIWAGYLDGDFHLLPHWDLDFAGRFEHYTDFGN
TENGKVSTRYDFTKRIAIRGTVSNGFRAPTLPEEHFSALNVSPTGATGLLSTTSAAGQSVGALPLKPERSFSAEAGLVLE
PVDGWHVSADVYQINIRDRIFGSSTFSDSDALNAIAMTGASLPAGITNSDVFVNYFANVGSTKTQGLDIMSDYLLRLNQY
GNVDLSLGVNLNRTKVTRTNTLANGLPALNAQTASYLTNGAPKNKIVLQAHWTIGQWDVNVRQTRYGATTILQTYEDQAP
AALQYSNTQWLSFKNTAAWMTDLEVGYRLNHIWHFAVGANNIFNVRPRRLPLIANYLGANQFDQNSSGIPFTGGYYYGRI
NASF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=171, Percent_Identity=32.1637426900585, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790405, Length=168, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 94999; Mature: 94867

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRRSLIAATILAMQFDLSAALAQTAPSQTATPQKPATSGHRHVAKAGKKAGAPKAHAA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHC
TASAATPGVVPAAAVSTAAVAPVVPVAPVYHAPPPDAGEAVIVTGTHAYNRHARDSTAPI
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCE
TVISAATLQRTGAVNLADALTRMDPSITEQTMGADAGALTSSIRMRGLNPNEVLVLVDGK
EEEEEHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHEECCCCCCCEEEEECCC
RRHTTANIYADQGPQQGSTPVDLNMLPANAIDHIEILRDGAAAMYGSDAIAGVVNIITKK
CCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHH
TAHGLNLTGQTGANAYNGDGWQYQTGIDGGFSFLGDGYVHISGQVEHADHMVPKGASDLR
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCCEEEEECEECHHHCCCCCCCHHCC
TDPNNADYGGVNFPSNSNMIMSTPEETRENLLINFGKTVTEGIDFYGQITYAHRHSEAYE
CCCCCCCCCCCCCCCCCCEEEECCHHHHCCEEEECCCHHHHCCCCEEEEEEEEHHHHHHH
NYRTPTKAPQIYPAGFSPLETIDENDFAATLGLKGDNFLGFDWDVSTTYGQDDDTIGNKN
HCCCCCCCCEEEECCCCHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCC
TANPNMLSTDPTVCGTNPANAATYSTDGCGWSPTTVLAERYSLAQWTNNADFRRRLKIAN
CCCCCEECCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHEECCC
VVPVTVAFGAEHRLEQYQIWPGNPPSYQIGGTQGYAGLMPENAGKWGRDIWAGYLDGDFH
EEEEEEEECCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCHHHEEEEECCCEE
LLPHWDLDFAGRFEHYTDFGNTENGKVSTRYDFTKRIAIRGTVSNGFRAPTLPEEHFSAL
ECCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCHHHHCEE
NVSPTGATGLLSTTSAAGQSVGALPLKPERSFSAEAGLVLEPVDGWHVSADVYQINIRDR
ECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEHHE
IFGSSTFSDSDALNAIAMTGASLPAGITNSDVFVNYFANVGSTKTQGLDIMSDYLLRLNQ
ECCCCCCCCCHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
YGNVDLSLGVNLNRTKVTRTNTLANGLPALNAQTASYLTNGAPKNKIVLQAHWTIGQWDV
CCCEEEEECCCCCCEEEEECHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEECEEEEEEC
NVRQTRYGATTILQTYEDQAPAALQYSNTQWLSFKNTAAWMTDLEVGYRLNHIWHFAVGA
CEEEEECCHHHHHHHHCCCCCCEEEECCCEEEEECCCEEEEEEHHCCEEEEEEEEEEECC
NNIFNVRPRRLPLIANYLGANQFDQNSSGIPFTGGYYYGRINASF
CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCEECCEEEEEEECCC
>Mature Secondary Structure 
TLRRSLIAATILAMQFDLSAALAQTAPSQTATPQKPATSGHRHVAKAGKKAGAPKAHAA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHC
TASAATPGVVPAAAVSTAAVAPVVPVAPVYHAPPPDAGEAVIVTGTHAYNRHARDSTAPI
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCE
TVISAATLQRTGAVNLADALTRMDPSITEQTMGADAGALTSSIRMRGLNPNEVLVLVDGK
EEEEEHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHEECCCCCCCEEEEECCC
RRHTTANIYADQGPQQGSTPVDLNMLPANAIDHIEILRDGAAAMYGSDAIAGVVNIITKK
CCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHH
TAHGLNLTGQTGANAYNGDGWQYQTGIDGGFSFLGDGYVHISGQVEHADHMVPKGASDLR
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCCEEEEECEECHHHCCCCCCCHHCC
TDPNNADYGGVNFPSNSNMIMSTPEETRENLLINFGKTVTEGIDFYGQITYAHRHSEAYE
CCCCCCCCCCCCCCCCCCEEEECCHHHHCCEEEECCCHHHHCCCCEEEEEEEEHHHHHHH
NYRTPTKAPQIYPAGFSPLETIDENDFAATLGLKGDNFLGFDWDVSTTYGQDDDTIGNKN
HCCCCCCCCEEEECCCCHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCC
TANPNMLSTDPTVCGTNPANAATYSTDGCGWSPTTVLAERYSLAQWTNNADFRRRLKIAN
CCCCCEECCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHEECCC
VVPVTVAFGAEHRLEQYQIWPGNPPSYQIGGTQGYAGLMPENAGKWGRDIWAGYLDGDFH
EEEEEEEECCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCHHHEEEEECCCEE
LLPHWDLDFAGRFEHYTDFGNTENGKVSTRYDFTKRIAIRGTVSNGFRAPTLPEEHFSAL
ECCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCHHHHCEE
NVSPTGATGLLSTTSAAGQSVGALPLKPERSFSAEAGLVLEPVDGWHVSADVYQINIRDR
ECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEHHE
IFGSSTFSDSDALNAIAMTGASLPAGITNSDVFVNYFANVGSTKTQGLDIMSDYLLRLNQ
ECCCCCCCCCHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
YGNVDLSLGVNLNRTKVTRTNTLANGLPALNAQTASYLTNGAPKNKIVLQAHWTIGQWDV
CCCEEEEECCCCCCEEEEECHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEECEEEEEEC
NVRQTRYGATTILQTYEDQAPAALQYSNTQWLSFKNTAAWMTDLEVGYRLNHIWHFAVGA
CEEEEECCHHHHHHHHCCCCCCEEEECCCEEEEECCCEEEEEEHHCCEEEEEEEEEEECC
NNIFNVRPRRLPLIANYLGANQFDQNSSGIPFTGGYYYGRINASF
CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]