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The map label for this gene is yegE [H]

Identifier: 162149402

GI number: 162149402

Start: 3719753

End: 3721147

Strand: Direct

Name: yegE [H]

Synonym: GDI_3640

Alternate gene names: 162149402

Gene position: 3719753-3721147 (Clockwise)

Preceding gene: 162149401

Following gene: 162149403

Centisome position: 94.31

GC content: 68.39

Gene sequence:

>1395_bases
ATGCTCGTCTGGGACTTCATGGGGATGAAGCGGGCCACGAGATCGGCCCTTCGATCGGGGACGGGACGGGGACAGGTGCG
GGGGCACACGCGGGATTTCAACGAGATCATGGCGCTGGCCGTTGCGGGCAGCGGCACCGGCATCTGGGACCGCGACGTCG
TGACCGGCGAAATCCGCTATTCCGACGGCTGGGTCGAAATCCTGGGCTATCGCCCCGACGAGGTCAGCACACGGGTCGAG
GAGAGCTACGACCGCGTGCATCCCGATGACCTGGCCTATGTCCAGGCGACGATGGACGCCCATTTCGAGGGCCGCACCGA
TTTCTACGAGGCCGAATACCGGCTGCGCTGCCGGGACGGCGGCTATAAATGGGTGCTCAGCCGTGGCCGCGTCGTCAGCC
GCGATGCCCGGGGCAGGGCGCTGCGGATGGTGGGCACGACGACCGACATCAGCTCGATGCGTGCCCTGGCCGAGCGGCTG
CAGCAGAGCATCGAGCTGATCACCAACCTGACCAACCAGGTTCCGGGCCTGGTGTTCCAGTGCCTGCGCGCGCCCGACGG
CACGGCCCACATGCCCTATGCCAGCGCCAGGATCGACGAGATCTATGAACTGACGGCGGAACAGGTGGCGGTCAGCACCA
TCCCGGTCCATGAGCGTGTGCATCCCGACGACCTGGAGACCTATCGCGCGACGCTGGCCGCGGCTGCCGCGACGCTGACG
CCCTGGCATTGCGTCTTTCGCGTGCTGCTGCCGGAGCAGGGCCTGCGCTGGCGGCAGATCGACGCCCATCCGACCGGCCT
GCCCGACGGGGGCACGCTGTGGTACGGGCTGGTGGTGGACGTGACCGCGCGCAGGCGCATGGAACAGGAACTGCACGCCC
TGGCGCGGGTCGATCACCTGACCGGCCTGCCGAACCGCCGCGCCTTCACCGAAGGAATGGAAAGGGCCTGGCAGATGCTG
CGCGGTGGCGTCAGCCGGGGGGGCGCGGTGCTGATGATCGACATCGACCGGTTCAAGACCATCAACGACCGGTACGGCCA
TGCGGCGGGTGACGCGGTGCTGCGCCATGTCGCCACGGTGCTGATGGCCACGCTGCGCGCCACCGATTTTACCGGCCGCA
TGGGGGGCGAGGAATTCGCCGCCTGCCTGCCCGATACCGGCCTGGACGAGGCCGGCCGCATCGCCGAGCGTCTGCGCCAG
GCGATTGCGGGCACGCCGGTCCCCTTCGAAAGCCACAGCATCGCGCTGACGGTCAGTATCGGGATTTCGAAGATGCGCCT
GGCCGACGCCGGCGGCGACGATGCGCTGTCGCGGGCCGACATGGCCCTGTATTCGGCCAAGGAAAACGGCCGCGACCGCG
TGGCTTTCGCGACCCTGGAAGTCGAACGGGGATAG

Upstream 100 bases:

>100_bases
GCCGGAATGGCCCGCCGTTCGCGCGCACCTGCGGTTTTCCCTCGCCGCGCGGGCGTAACCCGGGTAAGGCGTCCCCTCGA
CCGGGCAGGACGCGTGTCAT

Downstream 100 bases:

>100_bases
GGTACGTTTTTTTCGTATCGGCGGTCTTTAACGGCGACGGAATCCGATTACATTCCCGTTCTGGCTTGAATATTTCCGAA
AAAAGGAAAATTCCCAGATA

Product: GGDEF family signaling protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLVWDFMGMKRATRSALRSGTGRGQVRGHTRDFNEIMALAVAGSGTGIWDRDVVTGEIRYSDGWVEILGYRPDEVSTRVE
ESYDRVHPDDLAYVQATMDAHFEGRTDFYEAEYRLRCRDGGYKWVLSRGRVVSRDARGRALRMVGTTTDISSMRALAERL
QQSIELITNLTNQVPGLVFQCLRAPDGTAHMPYASARIDEIYELTAEQVAVSTIPVHERVHPDDLETYRATLAAAAATLT
PWHCVFRVLLPEQGLRWRQIDAHPTGLPDGGTLWYGLVVDVTARRRMEQELHALARVDHLTGLPNRRAFTEGMERAWQML
RGGVSRGGAVLMIDIDRFKTINDRYGHAAGDAVLRHVATVLMATLRATDFTGRMGGEEFAACLPDTGLDEAGRIAERLRQ
AIAGTPVPFESHSIALTVSIGISKMRLADAGGDDALSRADMALYSAKENGRDRVAFATLEVERG

Sequences:

>Translated_464_residues
MLVWDFMGMKRATRSALRSGTGRGQVRGHTRDFNEIMALAVAGSGTGIWDRDVVTGEIRYSDGWVEILGYRPDEVSTRVE
ESYDRVHPDDLAYVQATMDAHFEGRTDFYEAEYRLRCRDGGYKWVLSRGRVVSRDARGRALRMVGTTTDISSMRALAERL
QQSIELITNLTNQVPGLVFQCLRAPDGTAHMPYASARIDEIYELTAEQVAVSTIPVHERVHPDDLETYRATLAAAAATLT
PWHCVFRVLLPEQGLRWRQIDAHPTGLPDGGTLWYGLVVDVTARRRMEQELHALARVDHLTGLPNRRAFTEGMERAWQML
RGGVSRGGAVLMIDIDRFKTINDRYGHAAGDAVLRHVATVLMATLRATDFTGRMGGEEFAACLPDTGLDEAGRIAERLRQ
AIAGTPVPFESHSIALTVSIGISKMRLADAGGDDALSRADMALYSAKENGRDRVAFATLEVERG
>Mature_464_residues
MLVWDFMGMKRATRSALRSGTGRGQVRGHTRDFNEIMALAVAGSGTGIWDRDVVTGEIRYSDGWVEILGYRPDEVSTRVE
ESYDRVHPDDLAYVQATMDAHFEGRTDFYEAEYRLRCRDGGYKWVLSRGRVVSRDARGRALRMVGTTTDISSMRALAERL
QQSIELITNLTNQVPGLVFQCLRAPDGTAHMPYASARIDEIYELTAEQVAVSTIPVHERVHPDDLETYRATLAAAAATLT
PWHCVFRVLLPEQGLRWRQIDAHPTGLPDGGTLWYGLVVDVTARRRMEQELHALARVDHLTGLPNRRAFTEGMERAWQML
RGGVSRGGAVLMIDIDRFKTINDRYGHAAGDAVLRHVATVLMATLRATDFTGRMGGEEFAACLPDTGLDEAGRIAERLRQ
AIAGTPVPFESHSIALTVSIGISKMRLADAGGDDALSRADMALYSAKENGRDRVAFATLEVERG

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=439, Percent_Identity=26.6514806378132, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=40.5405405405405, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87082007, Length=187, Percent_Identity=38.5026737967914, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=35.8024691358025, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787541, Length=193, Percent_Identity=33.160621761658, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=37.037037037037, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=32.0855614973262, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=30.939226519337, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=31.3253012048193, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87081977, Length=186, Percent_Identity=29.5698924731183, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=32.2784810126582, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787056, Length=232, Percent_Identity=28.448275862069, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=34.1317365269461, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788085, Length=202, Percent_Identity=29.2079207920792, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 51448; Mature: 51448

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWDFMGMKRATRSALRSGTGRGQVRGHTRDFNEIMALAVAGSGTGIWDRDVVTGEIRY
CEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCEEEEEEEE
SDGWVEILGYRPDEVSTRVEESYDRVHPDDLAYVQATMDAHFEGRTDFYEAEYRLRCRDG
CCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEECEEEEEEECC
GYKWVLSRGRVVSRDARGRALRMVGTTTDISSMRALAERLQQSIELITNLTNQVPGLVFQ
CEEEEEECCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLRAPDGTAHMPYASARIDEIYELTAEQVAVSTIPVHERVHPDDLETYRATLAAAAATLT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
PWHCVFRVLLPEQGLRWRQIDAHPTGLPDGGTLWYGLVVDVTARRRMEQELHALARVDHL
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEHEEHHHHHHHHHHHHHHHHHHHHH
TGLPNRRAFTEGMERAWQMLRGGVSRGGAVLMIDIDRFKTINDRYGHAAGDAVLRHVATV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCCHHCCCHHHHHHHHHHHHH
LMATLRATDFTGRMGGEEFAACLPDTGLDEAGRIAERLRQAIAGTPVPFESHSIALTVSI
HHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GISKMRLADAGGDDALSRADMALYSAKENGRDRVAFATLEVERG
CCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MLVWDFMGMKRATRSALRSGTGRGQVRGHTRDFNEIMALAVAGSGTGIWDRDVVTGEIRY
CEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCEEEEEEEE
SDGWVEILGYRPDEVSTRVEESYDRVHPDDLAYVQATMDAHFEGRTDFYEAEYRLRCRDG
CCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEECEEEEEEECC
GYKWVLSRGRVVSRDARGRALRMVGTTTDISSMRALAERLQQSIELITNLTNQVPGLVFQ
CEEEEEECCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLRAPDGTAHMPYASARIDEIYELTAEQVAVSTIPVHERVHPDDLETYRATLAAAAATLT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
PWHCVFRVLLPEQGLRWRQIDAHPTGLPDGGTLWYGLVVDVTARRRMEQELHALARVDHL
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEHEEHHHHHHHHHHHHHHHHHHHHH
TGLPNRRAFTEGMERAWQMLRGGVSRGGAVLMIDIDRFKTINDRYGHAAGDAVLRHVATV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCCHHCCCHHHHHHHHHHHHH
LMATLRATDFTGRMGGEEFAACLPDTGLDEAGRIAERLRQAIAGTPVPFESHSIALTVSI
HHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GISKMRLADAGGDDALSRADMALYSAKENGRDRVAFATLEVERG
CCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]