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The map label for this gene is ppa [H]

Identifier: 162149259

GI number: 162149259

Start: 3586665

End: 3587189

Strand: Direct

Name: ppa [H]

Synonym: GDI_3491

Alternate gene names: 162149259

Gene position: 3586665-3587189 (Clockwise)

Preceding gene: 162149256

Following gene: 162149270

Centisome position: 90.94

GC content: 63.62

Gene sequence:

>525_bases
ATGGATGTGTCGAAAATCTCGCCCGGCAAGGACGTACCGTTCGATATCAACGTCGTCATCGAGATCCCGCAGGGATCGTC
GGTGAAATACGAGATCGACAAGGACAGCGGCGCCATCGTCGTCGACCGCGTCCTGTTCACGCCGATGGCCTATCCGGCCG
CCTACGGCTTCATTCCCAACACGCTGGCCGCCGATGGCGACCCGGCCGACGCGCTGGTGCTGATCCCGGCCCCGGTGGTG
CCCGGCGCCGTGATCCGCGCGCGCCCGATCGGCATGCTGCGCATGGAAGACGAAAGCGGCCAGGACGAAAAGATCGTCTG
CGTGCCGCACGACAAGGTGCACCCGTACTATTCCAAGGTCGAGAAGATCGAGGACCTGCCCGAAATCGTCATCCAGGAGA
TCGAGCATTTCTTCACCCGCTACAAGGACCTGGAGAAGGGCAAGTGGGTCAAGGTGGCCGGCTGGGCCGGTCGCGAGGAA
GCGGGCGAGGTGATCAAGGCCTCGCTGGCGGCGGCCGAGAAGTAA

Upstream 100 bases:

>100_bases
TCGGCCGTTTGGCAAGCCTTATAGGGATGCTTGGCAATGGGGACACGCCTCGATAGGTTCGACGGTCTCTTTTCTGTTCC
GTAGAGTGTGGAGCGCCGCC

Downstream 100 bases:

>100_bases
GCCGGTGGGCCGGGGCCCCGCCCCGGCCTTTCCCGCCCCTACCGTTCCGCCCCGCGTCCGGCGGACAGGATGATCGCGGC
GCCCGCCAGGCAGATCGCGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDVSKISPGKDVPFDINVVIEIPQGSSVKYEIDKDSGAIVVDRVLFTPMAYPAAYGFIPNTLAADGDPADALVLIPAPVV
PGAVIRARPIGMLRMEDESGQDEKIVCVPHDKVHPYYSKVEKIEDLPEIVIQEIEHFFTRYKDLEKGKWVKVAGWAGREE
AGEVIKASLAAAEK

Sequences:

>Translated_174_residues
MDVSKISPGKDVPFDINVVIEIPQGSSVKYEIDKDSGAIVVDRVLFTPMAYPAAYGFIPNTLAADGDPADALVLIPAPVV
PGAVIRARPIGMLRMEDESGQDEKIVCVPHDKVHPYYSKVEKIEDLPEIVIQEIEHFFTRYKDLEKGKWVKVAGWAGREE
AGEVIKASLAAAEK
>Mature_174_residues
MDVSKISPGKDVPFDINVVIEIPQGSSVKYEIDKDSGAIVVDRVLFTPMAYPAAYGFIPNTLAADGDPADALVLIPAPVV
PGAVIRARPIGMLRMEDESGQDEKIVCVPHDKVHPYYSKVEKIEDLPEIVIQEIEHFFTRYKDLEKGKWVKVAGWAGREE
AGEVIKASLAAAEK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=175, Percent_Identity=52.5714285714286, Blast_Score=187, Evalue=4e-49,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19059; Mature: 19059

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSKISPGKDVPFDINVVIEIPQGSSVKYEIDKDSGAIVVDRVLFTPMAYPAAYGFIPN
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEHHHHHCCCHHHHHHCCCCC
TLAADGDPADALVLIPAPVVPGAVIRARPIGMLRMEDESGQDEKIVCVPHDKVHPYYSKV
CCCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCHHHHHH
EKIEDLPEIVIQEIEHFFTRYKDLEKGKWVKVAGWAGREEAGEVIKASLAAAEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVSKISPGKDVPFDINVVIEIPQGSSVKYEIDKDSGAIVVDRVLFTPMAYPAAYGFIPN
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEHHHHHCCCHHHHHHCCCCC
TLAADGDPADALVLIPAPVVPGAVIRARPIGMLRMEDESGQDEKIVCVPHDKVHPYYSKV
CCCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCHHHHHH
EKIEDLPEIVIQEIEHFFTRYKDLEKGKWVKVAGWAGREEAGEVIKASLAAAEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9055427 [H]