Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 162149248

GI number: 162149248

Start: 3578334

End: 3579239

Strand: Direct

Name: yafC [H]

Synonym: GDI_3480

Alternate gene names: 162149248

Gene position: 3578334-3579239 (Clockwise)

Preceding gene: 162149246

Following gene: 162149249

Centisome position: 90.72

GC content: 62.91

Gene sequence:

>906_bases
ATGGACAACCGGACAGGCGAAATGCAGGTCTTCGTTCGCGTCGTGGAGTGCGGCAGCTTTTCCGAGGCCGCGCGGCAATT
GTTCATGACGCCGTCCACCGTTTCCAAACTGATCGCACGACTTGAGTCCCGGCTGGGCGTTCGGCTTATCGAACGTTCGA
CCCGCCGCCTGTCGCTGAGCGCGGAGGGACAGCTCTATTACGAGCGCGGGCAGGCGCTGCTCGCCGAACTGGATGACATG
GAACAGACCGTCTCGCAGGGGATGCGTCATACGAGCGGTATCGTCCGGGTCAGCGCGTCGGTCGCGTTCGGTACCCTGGG
GCTGGAACCGCTGCTTCCGGCGTTCTGGTCGGCATGCCCCAACGTCATCGTCGATCTCTCATTGTCCGATGAGATCATCG
ATCTTTTTCTCGATCGCACCGACATCGCATTCCGCGTCGGCAAACTCGCGGATTCGACACTGACCACACAGCGGATCGGC
AGCGCGCGTCGGAAGATCGTCGCATCTCCCGCCTATCTTGCGCGGCATGGCACGCCGGACACGGTCGATGACCTGGCGCG
GCATAATTGTCTCGGATTCAATTTCCGTCGCGCGGCGCCCGTCTGGCCGCTCAGGGAAGGCGGCCGCATCGTCGATCGCA
TGGTGCATGGCACGCTGCTGGCCAATAACGGCGAAACCGTCCGGCGCCTCGCGGTCGCGGGGATGGGGCTGGCGCGACTG
GGAAATTATCATGTCCGCGAGGATATCGCCGCCGGTCGGCTGGTGGAGGTGCTGGCCCAGGCCGGAATCCATGACGAGGA
GGACATCCACGCCATTTATTCCGGCACGCAACGCATGCCGCAACGCATGCGGGTGTTCCTGGATTTCGTTATTCCGAAGC
TACGGGCGTTTCTGAACCCGGCGTGA

Upstream 100 bases:

>100_bases
GTCCACTCCTTGCTCCGAACGAACATGATGATGTGGATCGGGATTGATAATCCGACGCCGGTGCACAAAACTCATGAAAA
AATTTCACAGGCGAGGCGCC

Downstream 100 bases:

>100_bases
GGTGTCCCGGTAAAACGGATAATCGGTCTAGCCATGCGACACCATGCCGGGATCCATGCGTCGTCATAAATACCCGCCGC
GCGTTCGAAACCGTAGCCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDNRTGEMQVFVRVVECGSFSEAARQLFMTPSTVSKLIARLESRLGVRLIERSTRRLSLSAEGQLYYERGQALLAELDDM
EQTVSQGMRHTSGIVRVSASVAFGTLGLEPLLPAFWSACPNVIVDLSLSDEIIDLFLDRTDIAFRVGKLADSTLTTQRIG
SARRKIVASPAYLARHGTPDTVDDLARHNCLGFNFRRAAPVWPLREGGRIVDRMVHGTLLANNGETVRRLAVAGMGLARL
GNYHVREDIAAGRLVEVLAQAGIHDEEDIHAIYSGTQRMPQRMRVFLDFVIPKLRAFLNPA

Sequences:

>Translated_301_residues
MDNRTGEMQVFVRVVECGSFSEAARQLFMTPSTVSKLIARLESRLGVRLIERSTRRLSLSAEGQLYYERGQALLAELDDM
EQTVSQGMRHTSGIVRVSASVAFGTLGLEPLLPAFWSACPNVIVDLSLSDEIIDLFLDRTDIAFRVGKLADSTLTTQRIG
SARRKIVASPAYLARHGTPDTVDDLARHNCLGFNFRRAAPVWPLREGGRIVDRMVHGTLLANNGETVRRLAVAGMGLARL
GNYHVREDIAAGRLVEVLAQAGIHDEEDIHAIYSGTQRMPQRMRVFLDFVIPKLRAFLNPA
>Mature_301_residues
MDNRTGEMQVFVRVVECGSFSEAARQLFMTPSTVSKLIARLESRLGVRLIERSTRRLSLSAEGQLYYERGQALLAELDDM
EQTVSQGMRHTSGIVRVSASVAFGTLGLEPLLPAFWSACPNVIVDLSLSDEIIDLFLDRTDIAFRVGKLADSTLTTQRIG
SARRKIVASPAYLARHGTPDTVDDLARHNCLGFNFRRAAPVWPLREGGRIVDRMVHGTLLANNGETVRRLAVAGMGLARL
GNYHVREDIAAGRLVEVLAQAGIHDEEDIHAIYSGTQRMPQRMRVFLDFVIPKLRAFLNPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=37.8006872852234, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=29.8245614035088, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI145693193, Length=309, Percent_Identity=28.8025889967638, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=29.4736842105263, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=30.7958477508651, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=26.1324041811847, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787589, Length=256, Percent_Identity=29.296875, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788481, Length=301, Percent_Identity=27.5747508305648, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=29.8387096774194, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788706, Length=194, Percent_Identity=27.319587628866, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33357; Mature: 33357

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRTGEMQVFVRVVECGSFSEAARQLFMTPSTVSKLIARLESRLGVRLIERSTRRLSLS
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
AEGQLYYERGQALLAELDDMEQTVSQGMRHTSGIVRVSASVAFGTLGLEPLLPAFWSACP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCHHHHHHHHHHCCC
NVIVDLSLSDEIIDLFLDRTDIAFRVGKLADSTLTTQRIGSARRKIVASPAYLARHGTPD
HHEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
TVDDLARHNCLGFNFRRAAPVWPLREGGRIVDRMVHGTLLANNGETVRRLAVAGMGLARL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHCCCHHHH
GNYHVREDIAAGRLVEVLAQAGIHDEEDIHAIYSGTQRMPQRMRVFLDFVIPKLRAFLNP
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
A
C
>Mature Secondary Structure
MDNRTGEMQVFVRVVECGSFSEAARQLFMTPSTVSKLIARLESRLGVRLIERSTRRLSLS
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
AEGQLYYERGQALLAELDDMEQTVSQGMRHTSGIVRVSASVAFGTLGLEPLLPAFWSACP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCHHHHHHHHHHCCC
NVIVDLSLSDEIIDLFLDRTDIAFRVGKLADSTLTTQRIGSARRKIVASPAYLARHGTPD
HHEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
TVDDLARHNCLGFNFRRAAPVWPLREGGRIVDRMVHGTLLANNGETVRRLAVAGMGLARL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHCCCHHHH
GNYHVREDIAAGRLVEVLAQAGIHDEEDIHAIYSGTQRMPQRMRVFLDFVIPKLRAFLNP
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]