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The map label for this gene is cycY [H]

Identifier: 162149212

GI number: 162149212

Start: 3541024

End: 3541605

Strand: Direct

Name: cycY [H]

Synonym: GDI_3442

Alternate gene names: 162149212

Gene position: 3541024-3541605 (Clockwise)

Preceding gene: 162149211

Following gene: 162149213

Centisome position: 89.78

GC content: 71.65

Gene sequence:

>582_bases
ATGACCGGTACCGTGCCGCATCCCCCGAACCTGGCGCGGCGGCGCCTGCTGATGGCGGCGCCGCTGGCCGCCGCCGGGGT
GGCGGGAGTGGCGTTCTGGCGCATGCTGTCGGGCATGAGCCAGGGATCGTTCGACCCGCACGACATCCACGCCCCGGTGC
TGAACCGCCCGGTGCCCGATTTCAAGCTGCCGGACCAGACCCCCGGCCAGGGATTCGGCACCGCCGACCTGCGCGCGCTG
CAGGCGCCGGTCCTGGTGAATTTCTTCGCGTCCTGGTGCATCCCGTGCGTCGCGGAGATGCCCGAACTGAACGCATTGAA
GGACCGGCTGCCGATCTGGGGCATCGCCTACAAGGACAAGCCGGACGACGCCGCCGGCTTCGTGAAGCGCGCCGGCAACC
CCTACGCGCGCATCGCCGGCGACCTGTCGGGCATGACCGCCATCGACTGGGGCGTGTCCGGCGTGCCGGAATCCTTCCTG
GTCGGGCCGGGCGGCGTGATCCGCTGGCACAGCGCCGCCGCGCTGGACGCCGACACGGTTCGCGGCACGCTGCTGCCCCT
GGCCGCGAGCCTGCATTCATGA

Upstream 100 bases:

>100_bases
GGCTGATCATGGCGCTGGGCGGGGCGCTGTCGCTGTCCGACCGGCGGACGCGCGTCGGCGCGCCGCGCCGCGCCGCCGCC
CCCGGCATGGTGGCCGCGCA

Downstream 100 bases:

>100_bases
GGACCACGGCGCGCACCCTGCTGGTCACGCTGGTCCTGGCCGCCGGGCTGTCGCCCCTGGCGGCGGCGGCGGTCGACGAT
CCGTCGGAAATGCTGCCCGA

Product: thioredoxin disulfide isomerase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTGTVPHPPNLARRRLLMAAPLAAAGVAGVAFWRMLSGMSQGSFDPHDIHAPVLNRPVPDFKLPDQTPGQGFGTADLRAL
QAPVLVNFFASWCIPCVAEMPELNALKDRLPIWGIAYKDKPDDAAGFVKRAGNPYARIAGDLSGMTAIDWGVSGVPESFL
VGPGGVIRWHSAAALDADTVRGTLLPLAASLHS

Sequences:

>Translated_193_residues
MTGTVPHPPNLARRRLLMAAPLAAAGVAGVAFWRMLSGMSQGSFDPHDIHAPVLNRPVPDFKLPDQTPGQGFGTADLRAL
QAPVLVNFFASWCIPCVAEMPELNALKDRLPIWGIAYKDKPDDAAGFVKRAGNPYARIAGDLSGMTAIDWGVSGVPESFL
VGPGGVIRWHSAAALDADTVRGTLLPLAASLHS
>Mature_192_residues
TGTVPHPPNLARRRLLMAAPLAAAGVAGVAFWRMLSGMSQGSFDPHDIHAPVLNRPVPDFKLPDQTPGQGFGTADLRALQ
APVLVNFFASWCIPCVAEMPELNALKDRLPIWGIAYKDKPDDAAGFVKRAGNPYARIAGDLSGMTAIDWGVSGVPESFLV
GPGGVIRWHSAAALDADTVRGTLLPLAASLHS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=177, Percent_Identity=34.4632768361582, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20399; Mature: 20268

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTVPHPPNLARRRLLMAAPLAAAGVAGVAFWRMLSGMSQGSFDPHDIHAPVLNRPVPD
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCC
FKLPDQTPGQGFGTADLRALQAPVLVNFFASWCIPCVAEMPELNALKDRLPIWGIAYKDK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCC
PDDAAGFVKRAGNPYARIAGDLSGMTAIDWGVSGVPESFLVGPGGVIRWHSAAALDADTV
CCHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCCHHHEECCCCEEEECCCHHCCHHHH
RGTLLPLAASLHS
HHHHHHHHHHHCC
>Mature Secondary Structure 
TGTVPHPPNLARRRLLMAAPLAAAGVAGVAFWRMLSGMSQGSFDPHDIHAPVLNRPVPD
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCC
FKLPDQTPGQGFGTADLRALQAPVLVNFFASWCIPCVAEMPELNALKDRLPIWGIAYKDK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCC
PDDAAGFVKRAGNPYARIAGDLSGMTAIDWGVSGVPESFLVGPGGVIRWHSAAALDADTV
CCHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCCHHHEECCCCEEEECCCHHCCHHHH
RGTLLPLAASLHS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]