Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 162148925

GI number: 162148925

Start: 3244933

End: 3245955

Strand: Direct

Name: trxB [H]

Synonym: GDI_3155

Alternate gene names: 162148925

Gene position: 3244933-3245955 (Clockwise)

Preceding gene: 162148921

Following gene: 162148926

Centisome position: 82.27

GC content: 65.59

Gene sequence:

>1023_bases
GTGTCCAGCGCATTGGACGGCCATATCCCCTGCATTGTGATCACATCGACGCCCGAGTCCATGACCCAGACCCATACCAC
CGACCTTCTTGTCATCGGCGCCGGCCCCGCCGGCTATACCGCCGCGATCTATGCCGCGCGCGCCAACCTGAAGCCCATCC
TGGTGGCCGGCCTGCAGCCGGGCGGACAGTTGATGATCACCACCGACGTGTATAATTACCCGGGCTTCGCCCGCGGCATC
CAGGGCCCCGAACTGATGGAACAGATGGCGGCCCAAGCCGCGCATGTGGGTACGCAGATCATCCACGACATCATCACCGA
ATGCACTCTGAAGGGTCACGGCGGGGCGGGCGAACCGTTCCGCCTGGTCGGCGATTCCGGTGACGTCTACCTGGCCCGCT
CGGTCGTCATCGCCACCGGGGCACAGGCCAAGTGGCTGGGCATTCCCGGCGAGGCCCAATACCAGGGGTCCGGGGTTTCG
GCCTGCGCCACCTGTGACGGATTCTTCTATCGCGGCCGGACCGTCGCCGTCATCGGCGGCGGCAACACGGCGGTCGAGGA
AGCGCTGTACCTGACCCATCATGCCGAACATGTGATCCTGATCCACCGGCGCGACAGCCTGCGCGCGGAAAAGATCCTGC
AGGACCGGCTGTTCGCCCACCCCAAGATCACGGTGAAATGGAATTGCGTGGTGGACGAGATCGTGGCCACCGGCACCCCG
CCCGTCGTCACGGGCCTGAATCTGCGCGATATTTCATCGGGCACGAACGAACACCTGGCGGTCGACGGCGTTTTCGTCGC
GATCGGGCATGCCCCGAACACGGCGGTTTTCAAGGACCAGGTCGAAACCGACGACGAGGGATATATCGTCACCAACCCGG
GCGGCACGCGCACGTCGGTGCCGGGCGTCTTCGCCGCCGGAGACGTGCAGGACCGCATTTACCGCCAGGCCGTTACCGCG
GCGGGAACCGGCTGCATGGCCGCGCTGGAGGCGGAACGTTACCTGGCGGGAATGTCGCACTGA

Upstream 100 bases:

>100_bases
CAGGTCCATCACTTCAGTCATTTCCGTCCCAAATCTGATGGCGCGCAGGATATGGCATGCGCCCGTTGCCGAAAAGGGCG
CAGCAGATCCCGCGCGCCTT

Downstream 100 bases:

>100_bases
ATACCATAAATCCTTGACCGGATCGGGTATTTCCGTCACCAGAACCAGATTGTAACGACAGGTTCTCCAGCCAGGATCGG
AATGCAGCGTTGGACTGGGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSSALDGHIPCIVITSTPESMTQTHTTDLLVIGAGPAGYTAAIYAARANLKPILVAGLQPGGQLMITTDVYNYPGFARGI
QGPELMEQMAAQAAHVGTQIIHDIITECTLKGHGGAGEPFRLVGDSGDVYLARSVVIATGAQAKWLGIPGEAQYQGSGVS
ACATCDGFFYRGRTVAVIGGGNTAVEEALYLTHHAEHVILIHRRDSLRAEKILQDRLFAHPKITVKWNCVVDEIVATGTP
PVVTGLNLRDISSGTNEHLAVDGVFVAIGHAPNTAVFKDQVETDDEGYIVTNPGGTRTSVPGVFAAGDVQDRIYRQAVTA
AGTGCMAALEAERYLAGMSH

Sequences:

>Translated_340_residues
MSSALDGHIPCIVITSTPESMTQTHTTDLLVIGAGPAGYTAAIYAARANLKPILVAGLQPGGQLMITTDVYNYPGFARGI
QGPELMEQMAAQAAHVGTQIIHDIITECTLKGHGGAGEPFRLVGDSGDVYLARSVVIATGAQAKWLGIPGEAQYQGSGVS
ACATCDGFFYRGRTVAVIGGGNTAVEEALYLTHHAEHVILIHRRDSLRAEKILQDRLFAHPKITVKWNCVVDEIVATGTP
PVVTGLNLRDISSGTNEHLAVDGVFVAIGHAPNTAVFKDQVETDDEGYIVTNPGGTRTSVPGVFAAGDVQDRIYRQAVTA
AGTGCMAALEAERYLAGMSH
>Mature_339_residues
SSALDGHIPCIVITSTPESMTQTHTTDLLVIGAGPAGYTAAIYAARANLKPILVAGLQPGGQLMITTDVYNYPGFARGIQ
GPELMEQMAAQAAHVGTQIIHDIITECTLKGHGGAGEPFRLVGDSGDVYLARSVVIATGAQAKWLGIPGEAQYQGSGVSA
CATCDGFFYRGRTVAVIGGGNTAVEEALYLTHHAEHVILIHRRDSLRAEKILQDRLFAHPKITVKWNCVVDEIVATGTPP
VVTGLNLRDISSGTNEHLAVDGVFVAIGHAPNTAVFKDQVETDDEGYIVTNPGGTRTSVPGVFAAGDVQDRIYRQAVTAA
GTGCMAALEAERYLAGMSH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=327, Percent_Identity=54.7400611620795, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI87081763, Length=317, Percent_Identity=35.6466876971609, Blast_Score=162, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=45.8860759493671, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6320560, Length=318, Percent_Identity=44.3396226415094, Blast_Score=272, Evalue=6e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35733; Mature: 35602

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSALDGHIPCIVITSTPESMTQTHTTDLLVIGAGPAGYTAAIYAARANLKPILVAGLQP
CCCCCCCCCCEEEEECCCHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCC
GGQLMITTDVYNYPGFARGIQGPELMEQMAAQAAHVGTQIIHDIITECTLKGHGGAGEPF
CCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCE
RLVGDSGDVYLARSVVIATGAQAKWLGIPGEAQYQGSGVSACATCDGFFYRGRTVAVIGG
EEECCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCEEECCEEEEEEEC
GNTAVEEALYLTHHAEHVILIHRRDSLRAEKILQDRLFAHPKITVKWNCVVDEIVATGTP
CCHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEEEHHHHCCCC
PVVTGLNLRDISSGTNEHLAVDGVFVAIGHAPNTAVFKDQVETDDEGYIVTNPGGTRTSV
CEEECCCEEECCCCCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCCCCC
PGVFAAGDVQDRIYRQAVTAAGTGCMAALEAERYLAGMSH
CCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSALDGHIPCIVITSTPESMTQTHTTDLLVIGAGPAGYTAAIYAARANLKPILVAGLQP
CCCCCCCCCEEEEECCCHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCC
GGQLMITTDVYNYPGFARGIQGPELMEQMAAQAAHVGTQIIHDIITECTLKGHGGAGEPF
CCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCE
RLVGDSGDVYLARSVVIATGAQAKWLGIPGEAQYQGSGVSACATCDGFFYRGRTVAVIGG
EEECCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCEEECCEEEEEEEC
GNTAVEEALYLTHHAEHVILIHRRDSLRAEKILQDRLFAHPKITVKWNCVVDEIVATGTP
CCHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEEEHHHHCCCC
PVVTGLNLRDISSGTNEHLAVDGVFVAIGHAPNTAVFKDQVETDDEGYIVTNPGGTRTSV
CEEECCCEEECCCCCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCCCCC
PGVFAAGDVQDRIYRQAVTAAGTGCMAALEAERYLAGMSH
CCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]