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The map label for this gene is acoC [H]

Identifier: 162147504

GI number: 162147504

Start: 1743152

End: 1744276

Strand: Reverse

Name: acoC [H]

Synonym: GDI_1720

Alternate gene names: 162147504

Gene position: 1744276-1743152 (Counterclockwise)

Preceding gene: 162147505

Following gene: 162147487

Centisome position: 44.22

GC content: 69.69

Gene sequence:

>1125_bases
ATGACTGATTCCATTACGCCCATCACGATGCCCAAGTTCGGCCTGGCGATGACCGAGGGCAAGCTGGCCGGCTGGATGGT
CCGCCCCGGTACCAGCGTGAAGGCCGGCGACGACCTGGCGGATATCGAGACCAGCAAGATCACCAACGCCTATGAAAGCC
CGGCCGGCGGCGTGCTGCGCCGCCAGGTGGCGGCGGAAGGCGACACGTTGCCGGTGGGCGCGCTGATCGGCGTGCTGGCC
GATGCCAGCGTGCCGGATGCCGAGATCGACGCCTTCATCACGCGCTTCAACGCCGAATTCTCCTCCGGCGCCGGCGGCGA
GGCCGAGGAAGCGGCCCCGGAACCGAAACTGGTGGACGTGCAGGGCAACAGCCTGCGGGTCCTGGACCTGGGCCATGGGG
ACGCCACGCCCATCGTGCTGGTCCACGGCTTCGGCGGTGATATCGGGAACTGGCTGTTCAACCACGCGGCCCTGGCCGCC
GGCCGGCGCGTCATCGCCTTCGACCTGCCCGGGCATGGCGGATCGACGAAGGATGTGGGCGCGGGGTCGCTGGATTTCTT
CGCCGGCATCGTCGTCGGGCTGCTGGACACGCTGGGCATCCCGCAGGCCCACCTGGTGGGGCATTCGCTGGGCGGCGGCG
TTGCCTTGACGGTGGCCCGGACCGCACCCGCGCGCGTCGCCTCCCTGGCGCTGATCGCGCCGGCCGGCATGGGCCCCGAG
ATCAACATGGACTTCATCACCGGGTTCATCACGGCCGACCGGCAGAAGACGATCCAGCCGGTCCTGGCCATGCTGGTCCA
TGACAAGACGCTGGTGGGGCGCAAGATGGCGGACGACGTCCTGCGCTACAAGCGCCTGGACGGCGCCGTCGCCGCCCTGA
CGCAGATTGCCGCCACCTGCTTCCCCGACGGCAAGCAGGCCGACGACCTGCGGCCCGTGCTGGAACAGGGCGACGTGAGG
GCGCTGATCCTGTGGGGCGAGGACGACGAGATCCTGCCCGCGAAGCAGTCCCGGGGCCTGCCGGGCCGCGTCACGATCGA
CCTCCTGCCCGGGGTCGGCCATATGCCGCAGATGGAGCGGGCGGCCGACATCAACAAGGCGATCGCGGCGTTCGTCGCGA
AATAG

Upstream 100 bases:

>100_bases
CGCATCGGTGCTGGAAAGCCTGTACCTGCCCGACGTGGCGAAGATCGAAGCGGCTGCCCGTGCCGTGATGACCCATCGCA
TCCGAGAGGTCGCCTGAACC

Downstream 100 bases:

>100_bases
AAACGATCTGTTCTATCCATGAGAAGGGCGGCGGCCGGTCAGTCCGGCCCCGCCCTTTTTTGTCCCGCAATCCGAACGGC
GCCATCTGGGCAGGCGCGCC

Product: branched-chain alpha-keto acid dehydrogenase subunit E2

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTDSITPITMPKFGLAMTEGKLAGWMVRPGTSVKAGDDLADIETSKITNAYESPAGGVLRRQVAAEGDTLPVGALIGVLA
DASVPDAEIDAFITRFNAEFSSGAGGEAEEAAPEPKLVDVQGNSLRVLDLGHGDATPIVLVHGFGGDIGNWLFNHAALAA
GRRVIAFDLPGHGGSTKDVGAGSLDFFAGIVVGLLDTLGIPQAHLVGHSLGGGVALTVARTAPARVASLALIAPAGMGPE
INMDFITGFITADRQKTIQPVLAMLVHDKTLVGRKMADDVLRYKRLDGAVAALTQIAATCFPDGKQADDLRPVLEQGDVR
ALILWGEDDEILPAKQSRGLPGRVTIDLLPGVGHMPQMERAADINKAIAAFVAK

Sequences:

>Translated_374_residues
MTDSITPITMPKFGLAMTEGKLAGWMVRPGTSVKAGDDLADIETSKITNAYESPAGGVLRRQVAAEGDTLPVGALIGVLA
DASVPDAEIDAFITRFNAEFSSGAGGEAEEAAPEPKLVDVQGNSLRVLDLGHGDATPIVLVHGFGGDIGNWLFNHAALAA
GRRVIAFDLPGHGGSTKDVGAGSLDFFAGIVVGLLDTLGIPQAHLVGHSLGGGVALTVARTAPARVASLALIAPAGMGPE
INMDFITGFITADRQKTIQPVLAMLVHDKTLVGRKMADDVLRYKRLDGAVAALTQIAATCFPDGKQADDLRPVLEQGDVR
ALILWGEDDEILPAKQSRGLPGRVTIDLLPGVGHMPQMERAADINKAIAAFVAK
>Mature_373_residues
TDSITPITMPKFGLAMTEGKLAGWMVRPGTSVKAGDDLADIETSKITNAYESPAGGVLRRQVAAEGDTLPVGALIGVLAD
ASVPDAEIDAFITRFNAEFSSGAGGEAEEAAPEPKLVDVQGNSLRVLDLGHGDATPIVLVHGFGGDIGNWLFNHAALAAG
RRVIAFDLPGHGGSTKDVGAGSLDFFAGIVVGLLDTLGIPQAHLVGHSLGGGVALTVARTAPARVASLALIAPAGMGPEI
NMDFITGFITADRQKTIQPVLAMLVHDKTLVGRKMADDVLRYKRLDGAVAALTQIAATCFPDGKQADDLRPVLEQGDVRA
LILWGEDDEILPAKQSRGLPGRVTIDLLPGVGHMPQMERAADINKAIAAFVAK

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=110, Percent_Identity=40, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081721, Length=284, Percent_Identity=28.8732394366197, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 38839; Mature: 38708

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSITPITMPKFGLAMTEGKLAGWMVRPGTSVKAGDDLADIETSKITNAYESPAGGVLR
CCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCHHHCHHHHHHHHHCCCCCHHHH
RQVAAEGDTLPVGALIGVLADASVPDAEIDAFITRFNAEFSSGAGGEAEEAAPEPKLVDV
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEEE
QGNSLRVLDLGHGDATPIVLVHGFGGDIGNWLFNHAALAAGRRVIAFDLPGHGGSTKDVG
CCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
AGSLDFFAGIVVGLLDTLGIPQAHLVGHSLGGGVALTVARTAPARVASLALIAPAGMGPE
CCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCHHHHHEEEEECCCCCCC
INMDFITGFITADRQKTIQPVLAMLVHDKTLVGRKMADDVLRYKRLDGAVAALTQIAATC
CCHHHHEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPDGKQADDLRPVLEQGDVRALILWGEDDEILPAKQSRGLPGRVTIDLLPGVGHMPQMER
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCHHH
AADINKAIAAFVAK
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TDSITPITMPKFGLAMTEGKLAGWMVRPGTSVKAGDDLADIETSKITNAYESPAGGVLR
CCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCHHHCHHHHHHHHHCCCCCHHHH
RQVAAEGDTLPVGALIGVLADASVPDAEIDAFITRFNAEFSSGAGGEAEEAAPEPKLVDV
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEEE
QGNSLRVLDLGHGDATPIVLVHGFGGDIGNWLFNHAALAAGRRVIAFDLPGHGGSTKDVG
CCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
AGSLDFFAGIVVGLLDTLGIPQAHLVGHSLGGGVALTVARTAPARVASLALIAPAGMGPE
CCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCHHHHHEEEEECCCCCCC
INMDFITGFITADRQKTIQPVLAMLVHDKTLVGRKMADDVLRYKRLDGAVAALTQIAATC
CCHHHHEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPDGKQADDLRPVLEQGDVRALILWGEDDEILPAKQSRGLPGRVTIDLLPGVGHMPQMER
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCHHH
AADINKAIAAFVAK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]