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The map label for this gene is hutI [H]

Identifier: 162138539

GI number: 162138539

Start: 1894059

End: 1895264

Strand: Reverse

Name: hutI [H]

Synonym: XCV1679

Alternate gene names: 162138539

Gene position: 1895264-1894059 (Counterclockwise)

Preceding gene: 78047239

Following gene: 78047234

Centisome position: 36.6

GC content: 68.24

Gene sequence:

>1206_bases
ATGCATTGCGACGTTCTGTGGCACAACGCGCAACTGATGACCCTGGATGCGGCCGATGGCGGCCTGGGCATCGTGGACGA
TGGCATCGTCGCCTGCCGGCACGGCCATATCGTCTACGCCGGCGCGGCCGCACAGGCCCCAGCGCTGCAGCCCGACAGTG
CGCACGACTGCCGGCGCCGCTGGATCAGCCCCGGCCTGATCGATTGCCACACGCACCTGGTGTACGCCGGCAACCGTGCC
AATGAGTTCGAGCAACGCCTGCGCGGCGCCAGCTATGCCGACATCGCCGCAGCCGGCGGCGGCATCGTGGCGACGGTGCG
CGCCACCCGCGCCGCCGACGATGCGGCGTTGCTGGCCGCCAGCCTGCCGCGCCTGGATGCGATGCTTGGCGAAGGCGTCA
CCACGCTGGAAATCAAATCCGGCTACGGGCTCACGCTGGACGATGAAGTCAAGCAGCTGCGCGTGGCGCGCCAACTCGCC
GCGCTGCGCAAGGTGGAAGTGGTGCCGACCTTCCTGGGCGCGCATGCCGTGCCGCCTGGTGGGCAGGCGCAGCACTACAT
CGACCAGGTCTGCACGCAGATGATTCCGGCGATCGCCACGCAAGGGCTTGCCGAGGCCGTGGACGTGTTCTGCGAGCATC
TGGCGTTCTCGCAGGCGCAGGCCGAAAAAGTCTTCGTTGCGGCGCAAGCGCATGGTTTGCGCATCAAGATCCACGCCGAA
CAATTGAGCAACCAGCACGGCGCCGAACTGGCCGCACGCTACGGCGCGTTGTCGGCCGATCACATCGAGTACCTGGACCA
GACGGGCATTGCGGCGATGGCCGCTGCCGGCACCGTGGCAGTGCTGCTGCCAGGCGCGTTCTACTTCACCCGCGATACCC
AACTGCCACCGATTGCCGCGCTGCGCACGGCCGGCGTGCCGCTGGCGCTGGCCACCGATTGCAACCCGGGCACCTCGCCG
CTGACCAGCCCGCTGCTGGCGATGAACATGGCGGCGACGTTGTTCCGCATGACCGTGGACGAATGCATCGCCGGGTTCAC
CCGCGAGGCTGCGCGGGCGCTTGGCCGCAGCGAGCGCCTGGGCCAGTTGCGCGCCGGCATGGACTGCGACCTGGCGATCT
GGAACATCGATGCGCCGGCCGATCTGGTCTACCGCATGGGCTTCAATCCTCTTCATGCCCGCGTCTGGCGCGGGCATCTG
TGCTGA

Upstream 100 bases:

>100_bases
CCCGGGCTGCCCAGAACACCTGCGTCTGTTGGTCTGCCACTGGACACCCTCGATCGCCGAACTTATTGTATATACATATC
AGACACCACGAGCCTGCGCC

Downstream 100 bases:

>100_bases
ATCCGGAGTCGTCATGAGTGTTTCTGTTGTCTTGCAACCCGGCCGGGTCACGCTGGCGCAATGGCGTGCGCTGTATCGCG
GTGCCGACGTCGCGTTGGAC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGIVACRHGHIVYAGAAAQAPALQPDSAHDCRRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEVKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGQAQHYIDQVCTQMIPAIATQGLAEAVDVFCEHLAFSQAQAEKVFVAAQAHGLRIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQTGIAAMAAAGTVAVLLPGAFYFTRDTQLPPIAALRTAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGQLRAGMDCDLAIWNIDAPADLVYRMGFNPLHARVWRGHL
C

Sequences:

>Translated_401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGIVACRHGHIVYAGAAAQAPALQPDSAHDCRRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEVKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGQAQHYIDQVCTQMIPAIATQGLAEAVDVFCEHLAFSQAQAEKVFVAAQAHGLRIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQTGIAAMAAAGTVAVLLPGAFYFTRDTQLPPIAALRTAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGQLRAGMDCDLAIWNIDAPADLVYRMGFNPLHARVWRGHL
C
>Mature_401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGIVACRHGHIVYAGAAAQAPALQPDSAHDCRRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEVKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGQAQHYIDQVCTQMIPAIATQGLAEAVDVFCEHLAFSQAQAEKVFVAAQAHGLRIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQTGIAAMAAAGTVAVLLPGAFYFTRDTQLPPIAALRTAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGQLRAGMDCDLAIWNIDAPADLVYRMGFNPLHARVWRGHL
C

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=337, Percent_Identity=37.0919881305638, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17555004, Length=342, Percent_Identity=34.7953216374269, Blast_Score=197, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 42572; Mature: 42572

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCDVLWHNAQLMTLDAADGGLGIVDDGIVACRHGHIVYAGAAAQAPALQPDSAHDCRRR
CCCEEEEECCEEEEEECCCCCCCEECCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHH
WISPGLIDCHTHLVYAGNRANEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAA
HCCCCEEECEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEHHCCCCHHHHHHH
SLPRLDAMLGEGVTTLEIKSGYGLTLDDEVKQLRVARQLAALRKVEVVPTFLGAHAVPPG
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GQAQHYIDQVCTQMIPAIATQGLAEAVDVFCEHLAFSQAQAEKVFVAAQAHGLRIKIHAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEHH
QLSNQHGAELAARYGALSADHIEYLDQTGIAAMAAAGTVAVLLPGAFYFTRDTQLPPIAA
HHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCEEEEEECCCEEEECCCCCCCHHH
LRTAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERL
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GQLRAGMDCDLAIWNIDAPADLVYRMGFNPLHARVWRGHLC
HHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MHCDVLWHNAQLMTLDAADGGLGIVDDGIVACRHGHIVYAGAAAQAPALQPDSAHDCRRR
CCCEEEEECCEEEEEECCCCCCCEECCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHH
WISPGLIDCHTHLVYAGNRANEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAA
HCCCCEEECEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEHHCCCCHHHHHHH
SLPRLDAMLGEGVTTLEIKSGYGLTLDDEVKQLRVARQLAALRKVEVVPTFLGAHAVPPG
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GQAQHYIDQVCTQMIPAIATQGLAEAVDVFCEHLAFSQAQAEKVFVAAQAHGLRIKIHAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEHH
QLSNQHGAELAARYGALSADHIEYLDQTGIAAMAAAGTVAVLLPGAFYFTRDTQLPPIAA
HHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCEEEEEECCCEEEECCCCCCCHHH
LRTAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERL
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GQLRAGMDCDLAIWNIDAPADLVYRMGFNPLHARVWRGHLC
HHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA