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The map label for this gene is pyrI [H]

Identifier: 161870949

GI number: 161870949

Start: 2086041

End: 2086397

Strand: Reverse

Name: pyrI [H]

Synonym: NMCC_2043

Alternate gene names: 161870949

Gene position: 2086397-2086041 (Counterclockwise)

Preceding gene: 161870950

Following gene: 161870948

Centisome position: 96.89

GC content: 54.62

Gene sequence:

>357_bases
TTGCACTACGGCAACGCAGTAACCGTGGGCTTCAACCTGCCCAGCAAAACCCAAGGCAGCAAAGACATCATCAAAATCAA
AGGCGTGTGCTTGGACGACAAAGCCGCCGACCGCCTTGCCCTGTTTGCACCCGAAGCAGTGGTCAACACCATCGACAATT
TCAAGGTTGTGCAGAAACGGCATTTGAACCTGCCCGACGAAATCGCCGAAGTGTTCCGCTGTCCGAACACGAATTGCGCC
GGCCACGGCGAGCCGGTCAAAAGCCGGTTTTATGTTAAAAAACACAACGGGCAGACGCGGCTGAAATGCCATTACTGCGA
AAAAACCTACAGCCGGGATTCGGTGGCGGAAGCCTGA

Upstream 100 bases:

>100_bases
GGAAACCCCGAAACTCAGTGTCGAAGCCATTGAAAAAGGTACGGTTATCGACCATATTCCCGCCGGCAGGGGGCTGACCA
TCCTGCGCCAGTTCAAACTT

Downstream 100 bases:

>100_bases
CGGATTCCCTTAAACCGAGTGGGCGGCATTTCGTCTGCCGCCTGTTTTGCCAATCTGAAATGGAATGATGATGCACGCTT
CTGTCCAAAGCCGTTTCGCA

Product: aspartate carbamoyltransferase regulatory subunit

Products: phosphate; N-carbamoyl-L-aspartate

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKRHLNLPDEIAEVFRCPNTNCA
GHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA

Sequences:

>Translated_118_residues
MHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKRHLNLPDEIAEVFRCPNTNCA
GHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA
>Mature_118_residues
MHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKRHLNLPDEIAEVFRCPNTNCA
GHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA

Specific function: Involved in allosteric regulation of aspartate carbamoyltransferase [H]

COG id: COG1781

COG function: function code F; Aspartate carbamoyltransferase, regulatory subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrI family [H]

Homologues:

Organism=Escherichia coli, GI1790692, Length=109, Percent_Identity=49.5412844036697, Blast_Score=117, Evalue=3e-28,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020545
- InterPro:   IPR002801
- InterPro:   IPR020542
- ProDom:   PD006194 [H]

Pfam domain/function: PF01948 PyrI; PF02748 PyrI_C [H]

EC number: 2.1.3.2

Molecular weight: Translated: 13178; Mature: 13178

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKR
CCCCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHH
HLNLPDEIAEVFRCPNTNCAGHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA
CCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKR
CCCCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHH
HLNLPDEIAEVFRCPNTNCAGHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA
CCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: carbamoyl phosphate; L-aspartate

Specific reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA