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The map label for this gene is oxyR [H]

Identifier: 161870890

GI number: 161870890

Start: 2033863

End: 2034573

Strand: Reverse

Name: oxyR [H]

Synonym: NMCC_1979

Alternate gene names: 161870890

Gene position: 2034573-2033863 (Counterclockwise)

Preceding gene: 161870891

Following gene: 161870874

Centisome position: 94.48

GC content: 52.74

Gene sequence:

>711_bases
GTGTTGGAAGAGGCAGAGCTTATCAGGCATTTGGCAAATGAAGAACAAAACGAGCTGGAGGGTGCGTTCAAACTCGGGCT
GATTTTTACGGTTGCGCCGTACCTGCTGCCGAAACTGATTGTCTCGTTGCGCCGTACTGCACCGAAAATGCCTTTGATGT
TGGAAGAGAATTACACGCATACTTTGACCGAGTCGCTCAAACGCGGGGACGTTGATGCGATTATCGTTGCCGAACCGTTT
CAAGAGCCGGGCATTGTTACCGAACCCTTGTATGACGAACCGTTTTTCGTGATTGTCCCGAAAGGGCATTCATTTGAGGA
ACTGGATGCCGTTTCGCCCCGGATGCTGGGTGAGGAGCAGGTTTTGCTGCTGACGGAAGGCAACTGTATGCGGGATCAGG
TACTCTCAAGCTGTTCCGAATTGGCGGCGAAACAACGTATACAGGGGTTGACCAATACATTGCAGGGCAGCTCGATTAAT
ACAATCCGCCATATGGTTGCCAGCGGTTTGGCAATCAGCGTGTTGCCGGCAACCGCACTGACCGAAAACGATCATATGCT
GTTCAGCATTATTCCGTTTGAAGGTACGCCGCCAAGCCGGCGGGTCGTATTGGCGTACCGCCGCAATTTTGTCCGTCCGA
AGGCGTTGTCGGCGATGAAGGCGGCGATTATGCAGTCGCAGCTTCACGGGGTAAGTTTTATCCGCGACTAG

Upstream 100 bases:

>100_bases
GAAATTGGAAGAAGAGCTTGCCGTCTCTTTGTTTGACCGGAGCAGCAACGATATTATTACGACCGAGGCGGGGGAACGTA
TCGTTGCACAGGCGCGTAAG

Downstream 100 bases:

>100_bases
GCGCAGGCATTGTTTTCAAAACGCCATTTCCCTGAGCCGACAACACGGTATGCCAAGATATTGCCGTCATCATCGATTTT
GAGTATAGCATCGCCACGGA

Product: hydrogen peroxide-inducible genes activator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPF
QEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSIN
TIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFIRD

Sequences:

>Translated_236_residues
MLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPF
QEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSIN
TIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFIRD
>Mature_236_residues
MLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPF
QEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSIN
TIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFIRD

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=210, Percent_Identity=31.9047619047619, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 26268; Mature: 26268

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTH
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHH
TLTESLKRGDVDAIIVAEPFQEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQ
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCHHCCCCE
VLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSINTIRHMVASGLAISVLPATAL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECHHHC
TENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFIRD
CCCCCEEEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTH
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHH
TLTESLKRGDVDAIIVAEPFQEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQ
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCHHCCCCE
VLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSINTIRHMVASGLAISVLPATAL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECHHHC
TENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFIRD
CCCCCEEEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]