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The map label for this gene is fur [H]

Identifier: 161870857

GI number: 161870857

Start: 1996616

End: 1997254

Strand: Reverse

Name: fur [H]

Synonym: NMCC_1944

Alternate gene names: 161870857

Gene position: 1997254-1996616 (Counterclockwise)

Preceding gene: 161870859

Following gene: 161870855

Centisome position: 92.75

GC content: 49.45

Gene sequence:

>639_bases
GTGCAAATCGGGATGGGTAGTGTAACACTGCTTGAATATTTTATAAAAGCGAACGATAATCATACGATTAAGCGGTATCC
GCCCTGTCCGCGCATCGGCCGCCGGTGCGGTTTTACTATTGCAAACTGCTATGGTGCGATAGTGGGCAAACAGGCCGAAA
TTGCGTATTATAACGTCTATTGTTTTACAGGGGTATTGAATATTATGGAAAAATTCAACAATATTGCACAACTGAAAGAC
AGCGGTCTGAAGGTTACCGGCCCGCGTTTGAAGATTTTGGATTTGTTCGAGACGCATGCGGAAGAGCATTTGAGTGCGGA
AGATGTGTACCGCATTTTGTTGGAAGAGGGTGTGGAAATCGGTGTGGCGACGATTTACCGCGTGCTGACCCAGTTTGAGC
AGGCGGGCATTCTGCAACGCCACCATTTTGAAACGGGCAAGGCGGTTTATGAGTTGGACAAGGGCGACCACCACGACCAT
ATCGTCTGCGTGAAGTGCGGCGAGGTAACGGAATTCCACAATCCCGAAATCGAAGCCCTGCAAGACAAAATCGCTGAGGA
AAACGGCTACCGCATCGTCGATCACGCGCTTTATATGTACGGCGTGTGCAGCGACTGTCAGGCCAAGGGCAAACGTTAA

Upstream 100 bases:

>100_bases
TACGAGGGGAACAGTGAAACGCGTTCGACGCTGCACGCGGCAAGGCCGAGGAGGGCGGAAAGGGCGAGGATGAGGGTTTT
GTTCACGGAAATGCCTTTCT

Downstream 100 bases:

>100_bases
ATCCGGACGGTTTGTTGTTCAGACGGCATTCATGATTTTGGATGCCGTCTGTGTTTTTGGAGAACTGCCATGCGTATTCC
GCTGCTTGCCCCTGACAATT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MQIGMGSVTLLEYFIKANDNHTIKRYPPCPRIGRRCGFTIANCYGAIVGKQAEIAYYNVYCFTGVLNIMEKFNNIAQLKD
SGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDH
IVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR

Sequences:

>Translated_212_residues
MQIGMGSVTLLEYFIKANDNHTIKRYPPCPRIGRRCGFTIANCYGAIVGKQAEIAYYNVYCFTGVLNIMEKFNNIAQLKD
SGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDH
IVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
>Mature_212_residues
MQIGMGSVTLLEYFIKANDNHTIKRYPPCPRIGRRCGFTIANCYGAIVGKQAEIAYYNVYCFTGVLNIMEKFNNIAQLKD
SGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDH
IVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=137, Percent_Identity=53.2846715328467, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 24032; Mature: 24032

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIGMGSVTLLEYFIKANDNHTIKRYPPCPRIGRRCGFTIANCYGAIVGKQAEIAYYNVY
CCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHH
CFTGVLNIMEKFNNIAQLKDSGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEI
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
GVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVTEFHNPEIEAL
HHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHH
QDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
HHHHHCCCCCCHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MQIGMGSVTLLEYFIKANDNHTIKRYPPCPRIGRRCGFTIANCYGAIVGKQAEIAYYNVY
CCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHH
CFTGVLNIMEKFNNIAQLKDSGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEI
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
GVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVTEFHNPEIEAL
HHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHH
QDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
HHHHHCCCCCCHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]