Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 161870851

GI number: 161870851

Start: 1988621

End: 1990075

Strand: Direct

Name: sdaA [H]

Synonym: NMCC_1934

Alternate gene names: 161870851

Gene position: 1988621-1990075 (Clockwise)

Preceding gene: 161870850

Following gene: 161870852

Centisome position: 92.35

GC content: 60.0

Gene sequence:

>1455_bases
GTGCCGCGTCTCCTTTTGGTTTGTCAAACGGAAGCCATACCGTCTGAAACCGCCTTTCGGAGCAAAACCATGGTCAGCAT
TTTTGATATTTTCAAAATCGGTATCGGGCCTTCCAGTTCGCATACGGTCGGCCCGATGAAGGCAGCCGCCGCCTTTGCGA
CAGGTTTGGATGCACAGGCTGTTCGCATCGTCATCGACATTTACGGCTCGCTCGCACTGACCGGATACGGACACGGTACA
TTTGACGCGCTGATGCTCGGTTTGGAAGGCAGCCTGCCGCACGACATCCCGCTTGCCGGCATTCCCGAACGCCTCGAACG
CATCCGCACGCAGCACATCCTCCGGCTCAACGGGCAAGAAATCCGCTTCATCCCCGACCGCGACCTGAACATACTCGGCA
ATCAAGTGCTGCCCAAACACCCCAACGGCCTGCGTTTTACCGCCTATGCTTCAGACGGCACGGTATTGAATGAACAGGTT
TATTATTCGGTCGGCGGCGGCTTTGTCGTTACCGAAGAAGATTTTGACCGGCAGGCGGAAACGGAAAAAGCCGTTCCCTA
TCCCTATACCAGTTGCGCCGAACTGCTTGCCCGATGCCGTCTGAACCGGCTCGACATCTCCGAAGTCGTGTTGGCAAACG
AAGCCGCGCTTGCCGGATGCGGCGAAGCCGAAATCCGCCGCCGCGCCGCTGCCGTTGCCGAGGTTATGGAAGGCTGCATC
AAACGCGGCTTGGGTGCGGACGGCGAACTGCCCGGCGGATTGAACGTCCGCCGCCGCGCCCCGCAGCTTGCCGCCAAGCT
CAAAGTCCTGCGCGAAACCGAAATCGTCAACACCCAGCTCTGGCCGATGGTGTACGCCATGGCGGTCAACGAAGAAAACG
CCGCCGGCGGACGCGTCGTTACCGCACCGACCAACGGCGCGGCAGGCATCATTCCCGCCGTATTGCACTATTTCCGCAAG
TTCAATCCGCACGCCACACAGGAACGCGTCGAAAACTTCCTGCTCACCGCAGGCGCAATCGGCATCCTCTACAAGACCAA
CGCCTCCATTTCCGGTGCGGATGTCGGCTGTCAGGGCGAAGTCGGCGTAGCGTGTTCGATGGCGGCGGGCGCATACGCCG
AAGTCATCGGCGGCACGCCCAAACAAGTGGAAAACGCCGCCGAAATGGCGATGGAACACCATTTGGGGCTGACTTGCGAC
CCCGTCGGCGGACTGGTGCAAATCCCCTGCATCGAGCGCAACGGCATCGCCGCCGAAAAAGCCCTCAAACTCGGCACGCT
CGCGCTTTTGGAAGACGGCACGGACAAAAAAGTCTCGCTCGACGAAGTCATCCGAACCATGCTGCAAACCGGCCGGGATA
TGAAGGCGACCTACAAAGAAACCTCTCTTGCCGGACTCGCCGCCACGCTCCGGAAAAAAGCCGTCCCCGTATCCGTGCGC
GTGGTCGAGTGCTGA

Upstream 100 bases:

>100_bases
GCGACGAGGTCGAGCCGCGCCGTGCCTTTATCGAAAACAACGCGCTGATTGCCCAAAATATCGACGCATAAGTGCCGTTT
TAAAAAAGGAGACGGGCATC

Downstream 100 bases:

>100_bases
GGATGGACAGAAACGAAAATGCCGTCTGAAAACAGTTTTTTAGACGGCATTTCATTTATTTCTTGCGGCTTTACCGTTTC
AGTGCCAGCGTCAACACGCC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MPRLLLVCQTEAIPSETAFRSKTMVSIFDIFKIGIGPSSSHTVGPMKAAAAFATGLDAQAVRIVIDIYGSLALTGYGHGT
FDALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQEIRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQV
YYSVGGGFVVTEEDFDRQAETEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCI
KRGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVVTAPTNGAAGIIPAVLHYFRK
FNPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGEVGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCD
PVGGLVQIPCIERNGIAAEKALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVR
VVEC

Sequences:

>Translated_484_residues
MPRLLLVCQTEAIPSETAFRSKTMVSIFDIFKIGIGPSSSHTVGPMKAAAAFATGLDAQAVRIVIDIYGSLALTGYGHGT
FDALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQEIRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQV
YYSVGGGFVVTEEDFDRQAETEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCI
KRGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVVTAPTNGAAGIIPAVLHYFRK
FNPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGEVGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCD
PVGGLVQIPCIERNGIAAEKALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVR
VVEC
>Mature_483_residues
PRLLLVCQTEAIPSETAFRSKTMVSIFDIFKIGIGPSSSHTVGPMKAAAAFATGLDAQAVRIVIDIYGSLALTGYGHGTF
DALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQEIRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQVY
YSVGGGFVVTEEDFDRQAETEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCIK
RGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVVTAPTNGAAGIIPAVLHYFRKF
NPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGEVGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCDP
VGGLVQIPCIERNGIAAEKALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVRV
VEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=453, Percent_Identity=52.0971302428256, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=50.6607929515419, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788116, Length=457, Percent_Identity=48.7964989059081, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 51689; Mature: 51558

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLLVCQTEAIPSETAFRSKTMVSIFDIFKIGIGPSSSHTVGPMKAAAAFATGLDAQA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHH
VRIVIDIYGSLALTGYGHGTFDALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQE
HEEEEEECCCEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCE
IRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQVYYSVGGGFVVTEEDFDRQAE
EEEECCCCCHHCCCCCCCCCCCCCEEEEEECCCEEECCEEEEEECCCEEEECCHHCCHHH
TEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCI
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHH
KRGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVV
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEEEECCCCCCCCEEE
TAPTNGAAGIIPAVLHYFRKFNPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGE
ECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCC
VGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCDPVGGLVQIPCIERNGIAAEK
CCEEEEHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCCHHH
ALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVR
HHHHCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
VVEC
EEEC
>Mature Secondary Structure 
PRLLLVCQTEAIPSETAFRSKTMVSIFDIFKIGIGPSSSHTVGPMKAAAAFATGLDAQA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHH
VRIVIDIYGSLALTGYGHGTFDALMLGLEGSLPHDIPLAGIPERLERIRTQHILRLNGQE
HEEEEEECCCEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCE
IRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQVYYSVGGGFVVTEEDFDRQAE
EEEECCCCCHHCCCCCCCCCCCCCEEEEEECCCEEECCEEEEEECCCEEEECCHHCCHHH
TEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCI
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHH
KRGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVV
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEEEECCCCCCCCEEE
TAPTNGAAGIIPAVLHYFRKFNPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGE
ECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCC
VGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCDPVGGLVQIPCIERNGIAAEK
CCEEEEHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCCHHH
ALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVR
HHHHCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
VVEC
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]