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The map label for this gene is nuoN [H]

Identifier: 161870805

GI number: 161870805

Start: 1935287

End: 1936732

Strand: Reverse

Name: nuoN [H]

Synonym: NMCC_1887

Alternate gene names: 161870805

Gene position: 1936732-1935287 (Counterclockwise)

Preceding gene: 161870806

Following gene: 161870804

Centisome position: 89.94

GC content: 55.19

Gene sequence:

>1446_bases
ATGAACTGGTCTGATTTGAATTTAATGCCCGCCATGCCCGAAATCGTGCTGCTTGCGCTGCTGGTGTTATTGTTGCTGGC
GGACTTGTGGGTCAGTGATGACAAACGCCGTTGGACGCATTACGGCGCGTTGGCAACGGTGGCGGTTACGGCTGTGGTGC
AGCTTGCCGTTTGGGAACAGGGCAGCACGTCTTCGTTCAACGGCATGTATATTGCAGACGGTATGTCGCGTTTGGCAAAA
ATGGTTTTATATGCCTTGACGTTTGCCCTGTTTGTTTATGCCAAGCCCTACAACCAAGTGCGCGGTATTTTCAAAGGCGA
GTTTTACACTCTGTCGCTGTTTGCCCTCTTGGGCATGAGCGTGATGGTGAGCGCGGGGCATTTTTTAACTGCCTATATCG
GTTTGGAACTCTTGTCGCTCGCCCTTTACGCCCTGATTGCCCTGCGCCGCGATTCCGGCTTTGCCGCCGAAGCCGCCTTG
AAATATTTTGTTCTGGGCGCGCTGGCATCCGGCCTGCTGCTCTACGGTATTTCTATGGTTTACGGCGCAACCGGTTCGCT
GGAATTTGCCGGCGTGCTCGCCTCTTCCTTCAATGAAGAAGCAAACGAATGGCTGTTGAAACTGGGTCTGGTGTTTATCG
TCGTCGCCGTTGCGTTCAAACTCGGCGCGGTGCCGTTCCATATGTGGGTGCCCGACGTGTATCACGGCGCGCCCACTTCT
GTTACCGCCCTGGTCGGCACTGCCCCGAAAGTCGCCGCCGTCGTTTTCGCTTTCCGCATCCTCGTTACCGGGCTGGGAAC
CGTGCATCATGACTGGTCTCTGATGTTTGCCCTGCTTGCCGCCGCCTCGCTGCTGGTCGGCAACCTTGCCGCTATCATGC
AGACCAATATCAAACGTATGCTCGCCTATTCCACCGTATCGCATATGGGGTTTATCCTGCTGGCGTTTATGGCGGGCGCG
GTCGGCTTTGCGGCGGGTCTCTATTACGCCATTACCTACGCGCTGATGGCGGCGGCAGGGTTCGGCGTGTTGATGGTGTT
GTCGGATGGGGACAACGAGTGCGAAAACATCAGCGATTTGGCAGGGCTGAACCAACACCGCGTATGGCTTGCCTTTTTGA
TGTTACTGGTTATGTTCTCTATGGCGGGCATTCCGCCGCTGATGGGTTTTTACGCCAAATTTGGCGTGATTATGGCACTC
TTAAAACAAGGCTATGTTTGGTTGTCCGTATTTGCCGTCGTGATGTCGCTGATTGGCGCGTTCTACTACCTGCGCGTGGT
CAAAGTCATGTATTTTGACGAATCCGGCCGCGCCCATCCCACCGTCGGCGGCAACAATGCCGCAAAATTCCTTTTGAGCG
TCAACGCGCTGCTGTTGGTGCTGTGGGGCATTATGCCGCAAACCGTTATCGACTGGTGCGCCAAGGCGTTGGAAAACACG
CTGTAA

Upstream 100 bases:

>100_bases
GGGTATGGGCCTGTATCCGAACGCATTTATCGAAGTGGTGCATCAGGCGGCAAACGATTTGATTGCCCATGTGGCACAAA
GCAAGATGTGAGGTGTGTAA

Downstream 100 bases:

>100_bases
GCCGCCGCAACGGCAGCCGTGTCAGAGGCTGCCGTTTTTGTTAAGATATGCCGTCCCGCAACGCAGTTCAGACGGCATCG
CCGCCGACAATGCCCAAACA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNWSDLNLMPAMPEIVLLALLVLLLLADLWVSDDKRRWTHYGALATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAK
MVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAAL
KYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTS
VTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGA
VGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMAL
LKQGYVWLSVFAVVMSLIGAFYYLRVVKVMYFDESGRAHPTVGGNNAAKFLLSVNALLLVLWGIMPQTVIDWCAKALENT
L

Sequences:

>Translated_481_residues
MNWSDLNLMPAMPEIVLLALLVLLLLADLWVSDDKRRWTHYGALATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAK
MVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAAL
KYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTS
VTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGA
VGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMAL
LKQGYVWLSVFAVVMSLIGAFYYLRVVKVMYFDESGRAHPTVGGNNAAKFLLSVNALLLVLWGIMPQTVIDWCAKALENT
L
>Mature_481_residues
MNWSDLNLMPAMPEIVLLALLVLLLLADLWVSDDKRRWTHYGALATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAK
MVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAAL
KYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTS
VTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGA
VGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMAL
LKQGYVWLSVFAVVMSLIGAFYYLRVVKVMYFDESGRAHPTVGGNNAAKFLLSVNALLLVLWGIMPQTVIDWCAKALENT
L

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=311, Percent_Identity=24.7588424437299, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI145693160, Length=485, Percent_Identity=32.3711340206186, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788614, Length=431, Percent_Identity=27.3781902552204, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788827, Length=357, Percent_Identity=26.6106442577031, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788613, Length=484, Percent_Identity=26.6528925619835, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788831, Length=407, Percent_Identity=23.3415233415233, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52042; Mature: 52042

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWSDLNLMPAMPEIVLLALLVLLLLADLWVSDDKRRWTHYGALATVAVTAVVQLAVWEQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GSTSSFNGMYIADGMSRLAKMVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMS
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHH
VMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAALKYFVLGALASGLLLYGISMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTS
HCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCH
VTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRM
HHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
AGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMALLKQGYVWLSVFAVVMSLIGA
HCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FYYLRVVKVMYFDESGRAHPTVGGNNAAKFLLSVNALLLVLWGIMPQTVIDWCAKALENT
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
L
C
>Mature Secondary Structure
MNWSDLNLMPAMPEIVLLALLVLLLLADLWVSDDKRRWTHYGALATVAVTAVVQLAVWEQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GSTSSFNGMYIADGMSRLAKMVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMS
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHH
VMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAALKYFVLGALASGLLLYGISMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTS
HCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCH
VTALVGTAPKVAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRM
HHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
AGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMALLKQGYVWLSVFAVVMSLIGA
HCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FYYLRVVKVMYFDESGRAHPTVGGNNAAKFLLSVNALLLVLWGIMPQTVIDWCAKALENT
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA