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The map label for this gene is ffh [H]

Identifier: 161870769

GI number: 161870769

Start: 1892391

End: 1893761

Strand: Direct

Name: ffh [H]

Synonym: NMCC_1850

Alternate gene names: 161870769

Gene position: 1892391-1893761 (Clockwise)

Preceding gene: 161870767

Following gene: 161870774

Centisome position: 87.88

GC content: 52.95

Gene sequence:

>1371_bases
ATGTTAGACAATTTAACCGGCCGCTTCAGCAATGTTCTCAAAAACATCCGCGGGCAGGCCAAACTGACCGAAGACAATAT
TAAAGAAGCCTTGCGCGAAGTCCGCCTCGCCCTGCTTGAGGCGGATGTCGCCCTGCCTGTCGTCAAAGAGTTCGTCAACA
ACGTCAAAGAAAAGGCCCTCGGTCAGGAAGTAGCGGGCAGCCTGACGCCGGATCAGGCATTTATCGGCGTGGTCAACAAA
GCCCTGACCGAGCTGATGGGCAGGGAAAACAAAACGCTGGATTTGTCGGTTGCGCCGCCCGCCGTCGTGTTGATGGCAGG
TTTGCAGGGCGCGGGCAAGACGACGACCGCCGGCAAACTCGCCCGCCTGCTGAAAAACGATCAGAAGAAAAAGGTTTTGG
TCGTATCTGCCGACGTTTACCGCCCTGCCGCGATTGAACAACTGCGTCTGTTGGCCGAACAGGTCGGCGTGGACTTTTTC
CCATCCGATACCAACCAAAAACCGGTTGAGATTGCAACTGCCGCCGTCGATTACGCCAAAAAACATTTTTACGATGTATT
GATGGTCGATACCGCCGGCCGTTTGGCAATCGATGAGGAGATGATGAACGAAATCAAAGCCCTTCACGCGGCGGTTAACC
CGGTGGAAACTTTGTTCGTCATCGATGCGATGCTGGGTCAGGATGCGGTGAACACTGCTCAGGCATTTAATGAAGCCCTG
CCGCTGACCGGTGTCGTATTGACCAAGATGGACGGCGATTCGCGCGGCGGCGCAGCTTTGTCCGTGCGCCACGTAACCGG
CAAGCCGATTAAATTTATCGGTGTCGGCGAAAAAATCAACGGCCTCGAACCTTTCCACCCCGACCGTCTTGCCAGCCGTA
TCCTCGGCATGGGCGACGTATTGACCCTGATTGAAGACGTCCAAAAAGGTATTGATGAAGAAGCCGCCGCCAAAATGGCG
AAAAAGCTACAAAAAGGCAAAGGCTTCGACCTCAACGACTTTAAAGAACAAATCCAGCAAATGCGCAATATGGGCGGTTT
GGAAAACCTGATGTCGAAAATGCCGGGCGAACTGGGTCAAATATCGAAACAAATCCCCGAAGGAACGGCTGAAAAAGCGA
TGGGCAAAGTGGAAGCCATCATCAACTCGATGACTCCAAAAGAACGCGCCAACCCTGCCCTGCTCAAAGCCAGCCGCAAA
CGCCGTATTGCAATGGGTGCGGGCACGACCGTACAGGAAGTGAACAAATTGCTCAAACAGTTTGAACAAATGCAACAAAT
GATGAAGATGTTCAGCGGCAACGGCTTGGGCAAACTGATGCGTATGGCGAAAGGAATGAAGGGAATGAAAGGAATGTTCC
CGGGTTTGTAA

Upstream 100 bases:

>100_bases
TGCTGTCCGGCACACAAGCCGCATCAAATTATTTTGATTTTATTTTAACAAAGAATGCCCCTGATGGGGCAAGCTATTCT
TATTCAGACCAAGGACCAGT

Downstream 100 bases:

>100_bases
GCCGATTTGACCGAAAACGCCGTCTAAAATTTCAGACGGCGTTTTTGTTTTATATTCTGATTTATAGTGGATTAACAAAA
ATCAGGACAAGGCGGCGAGC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVALPVVKEFVNNVKEKALGQEVAGSLTPDQAFIGVVNK
ALTELMGRENKTLDLSVAPPAVVLMAGLQGAGKTTTAGKLARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFF
PSDTNQKPVEIATAAVDYAKKHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETLFVIDAMLGQDAVNTAQAFNEAL
PLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVGEKINGLEPFHPDRLASRILGMGDVLTLIEDVQKGIDEEAAAKMA
KKLQKGKGFDLNDFKEQIQQMRNMGGLENLMSKMPGELGQISKQIPEGTAEKAMGKVEAIINSMTPKERANPALLKASRK
RRIAMGAGTTVQEVNKLLKQFEQMQQMMKMFSGNGLGKLMRMAKGMKGMKGMFPGL

Sequences:

>Translated_456_residues
MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVALPVVKEFVNNVKEKALGQEVAGSLTPDQAFIGVVNK
ALTELMGRENKTLDLSVAPPAVVLMAGLQGAGKTTTAGKLARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFF
PSDTNQKPVEIATAAVDYAKKHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETLFVIDAMLGQDAVNTAQAFNEAL
PLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVGEKINGLEPFHPDRLASRILGMGDVLTLIEDVQKGIDEEAAAKMA
KKLQKGKGFDLNDFKEQIQQMRNMGGLENLMSKMPGELGQISKQIPEGTAEKAMGKVEAIINSMTPKERANPALLKASRK
RRIAMGAGTTVQEVNKLLKQFEQMQQMMKMFSGNGLGKLMRMAKGMKGMKGMFPGL
>Mature_456_residues
MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVALPVVKEFVNNVKEKALGQEVAGSLTPDQAFIGVVNK
ALTELMGRENKTLDLSVAPPAVVLMAGLQGAGKTTTAGKLARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFF
PSDTNQKPVEIATAAVDYAKKHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETLFVIDAMLGQDAVNTAQAFNEAL
PLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVGEKINGLEPFHPDRLASRILGMGDVLTLIEDVQKGIDEEAAAKMA
KKLQKGKGFDLNDFKEQIQQMRNMGGLENLMSKMPGELGQISKQIPEGTAEKAMGKVEAIINSMTPKERANPALLKASRK
RRIAMGAGTTVQEVNKLLKQFEQMQQMMKMFSGNGLGKLMRMAKGMKGMKGMFPGL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=464, Percent_Identity=31.4655172413793, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI226371618, Length=403, Percent_Identity=31.5136476426799, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI295424842, Length=319, Percent_Identity=28.2131661442006, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI23308697, Length=319, Percent_Identity=28.5266457680251, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI89061728, Length=166, Percent_Identity=36.144578313253, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788963, Length=455, Percent_Identity=66.5934065934066, Blast_Score=599, Evalue=1e-172,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=34.3396226415094, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17539958, Length=444, Percent_Identity=30.4054054054054, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=302, Percent_Identity=29.4701986754967, Blast_Score=111, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=440, Percent_Identity=33.1818181818182, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI17647949, Length=454, Percent_Identity=31.9383259911894, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24641198, Length=321, Percent_Identity=26.4797507788162, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49451; Mature: 49451

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVALPVVKEFVNNVKEKAL
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVAGSLTPDQAFIGVVNKALTELMGRENKTLDLSVAPPAVVLMAGLQGAGKTTTAGKL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHHH
ARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFFPSDTNQKPVEIATAAVDYAK
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETLFVIDAMLGQDAVNTAQAFNEAL
HHHHHHHEECCCCCHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHCC
PLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVGEKINGLEPFHPDRLASRILGMGDV
CCCCEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCHHH
LTLIEDVQKGIDEEAAAKMAKKLQKGKGFDLNDFKEQIQQMRNMGGLENLMSKMPGELGQ
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHH
ISKQIPEGTAEKAMGKVEAIINSMTPKERANPALLKASRKRRIAMGAGTTVQEVNKLLKQ
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHEEECCCCCCHHHHHHHHHH
FEQMQQMMKMFSGNGLGKLMRMAKGMKGMKGMFPGL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLDNLTGRFSNVLKNIRGQAKLTEDNIKEALREVRLALLEADVALPVVKEFVNNVKEKAL
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVAGSLTPDQAFIGVVNKALTELMGRENKTLDLSVAPPAVVLMAGLQGAGKTTTAGKL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHHH
ARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFFPSDTNQKPVEIATAAVDYAK
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETLFVIDAMLGQDAVNTAQAFNEAL
HHHHHHHEECCCCCHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHCC
PLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVGEKINGLEPFHPDRLASRILGMGDV
CCCCEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCHHH
LTLIEDVQKGIDEEAAAKMAKKLQKGKGFDLNDFKEQIQQMRNMGGLENLMSKMPGELGQ
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHH
ISKQIPEGTAEKAMGKVEAIINSMTPKERANPALLKASRKRRIAMGAGTTVQEVNKLLKQ
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHEEECCCCCCHHHHHHHHHH
FEQMQQMMKMFSGNGLGKLMRMAKGMKGMKGMFPGL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]