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The map label for this gene is vapA [H]

Identifier: 161870758

GI number: 161870758

Start: 1876047

End: 1877906

Strand: Reverse

Name: vapA [H]

Synonym: NMCC_1832

Alternate gene names: 161870758

Gene position: 1877906-1876047 (Counterclockwise)

Preceding gene: 161870760

Following gene: 161870757

Centisome position: 87.21

GC content: 51.02

Gene sequence:

>1860_bases
ATGTTCAGAGCTCAGCTTGGTTCAAATACTCGTTCTACCAAAATCGGCGACGATGCCGATTTTTCATTTTCAGACAAGCC
GAAACCCGGCACTTCCCATTATTTTTCCAGCGGTAAAACCGATCAAAATTCATCCGAATATGGGTATGACGAAATCAATA
TCCAAGGTAAAAATTACAATAGCGGCATCCTCGCCGTCGATAATATGCCCGTTGTTAAGAAATATATTACAGATACTTAC
GGGGATAATTTAAAGGATGCGGTTAAGAAGCAATTACAGGATTTATACAAAACAAGACCCGAAGCTTGGGAAGAAAATAA
AAAACGGACTGAGGAGGCGTATATAGAACAGCTTGGACCAAAATTTAGTATACTCAAACAGAAAAACCCCGATTTAATTA
ATAAATTGGTAGAAGATTCCGTACTCACTCCTCATAGTAATACATCACAGACTAGTCTCAACAACATCTTCAATAAAAAA
TTACACGTCAAAATCGAAAACAAATCCCACGTCGCCGGACAGGTGTTGGAACTGACCAAGATGACGCTGAAAGATTCCCT
TTGGGAACCGCGCCGCCATTCCGACATCCATATGCTGGAAACTTCCGATAATGCCCGCATCCGCCTGAACACGAAAGATG
AAAAACTGACCGTCCATAAAGCGTATCAGGGCGGCGCGGATTTCCTGTTCGGCTACGACGTGCGGGAGTCGGACAAACCC
GCCCTGACCTTTGAAGACAAAGTCAGCGGAAAATCCGGCGTGGTTTTGGAACGCCGGCCGGAAAATCTGAAAACGCTCGA
CGGGCGCAAACTGATTGCGGCGGAAAAGGCAGACTCTAATTCGTTTGCGTTTAAACAAAATTACCGGCAGGGACTGTACG
AATTATTGCTCAAGCAATGCGAAGGCGGATTTTGCTTGGGCGTGCAGCGTTTGGCTATCCCCGAGGCGGAAGCGGTTTTA
TATGCCCAACAGGCTTATGCGGCAAATACTTTGTTCGGGCTGCGTGCCGCCGACAGGGGCGACGACGTGTATGCCGCCGA
TCCGTCCCGTCAAAAATTGTGGCTGCGCTTCATCGGCGGCCGGTCGCATCAAAATATACGGGGCGGCGCGGCTGCGGACG
GGCGGCGCAAAGGCGTGCAAATCGGCGGCGAGGTGTTTGTACGGCAAAATGAAGGCAGCCGACTGGCAATCGGCGTGATG
GGCGGCAGGGCCGGCCAGCACGCATCAGTCAACGGCAAAGGCGGTGCGGCAGGCAGTTATTTGTATGGTTATGGCGGGGG
TGTTTATGCTGCGTGGCATCAGTTGCGCGATAAACAAACGGGTGCGTATTTGGACGGCTGGTTGCAATACCAACGTTTCA
AACACCGCATCAATGATGAAAACCGTGCGGAACGCTACAAAACCAAAGGTTGGACGGCTTCTGTCGAAGGCGGCTACAAC
GCGCTTGTGGCGGAAGGCATTGTCGGAAAAGGCAATAATGTGCGGTTTTACCTACAACCGCAGGCGCAGTTTACCTACTT
GGGCGTAAACGGCGGCTTTACCGACAGCGAGGGGACGGCGGTCGGACTGCTCGGCAGCGGTCAGTGGCAAAGCCGCGCCG
GCATTCGGGCAAAAACCCGTTTTGCTTTGCGTAATGGTGTCAATCTTCAGCCTTTTGCCGCTTTTAATGTTTTGCACAGG
TCAAAATCTTTCGGCGTGGAAATGGACGGCGAAAAACAGACGCTGGCAGGCAGGACGGCACTCGAAGGGCGGTTCGGCAT
TGAAGCCGGTTGGAAAGGCCATATGTCCGCACGCATCGGATACGGCAAAAGGACGGACGGCGACAAAGAAGCCGCATTGT
CGCTCAAATGGCTGTTTTGA

Upstream 100 bases:

>100_bases
TGATCCTGAAGTTCTTCCGCGATTCATTTTAGAAGCGGCGGAAAACAGAGATTCCCACGTTTGGCGCGGTCCGTGCAGCA
TATCTTTTGATTGCTTCGGT

Downstream 100 bases:

>100_bases
TGCGTCGGGAAATGTTTTGACGTACAGGCGGCACACCGGCACGGCACCGCGCGCCGCCCCGCAAACCAATCCGAACCCTG
CTGCCCCGAAGGGCGGGGCA

Product: virulence associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MFRAQLGSNTRSTKIGDDADFSFSDKPKPGTSHYFSSGKTDQNSSEYGYDEINIQGKNYNSGILAVDNMPVVKKYITDTY
GDNLKDAVKKQLQDLYKTRPEAWEENKKRTEEAYIEQLGPKFSILKQKNPDLINKLVEDSVLTPHSNTSQTSLNNIFNKK
LHVKIENKSHVAGQVLELTKMTLKDSLWEPRRHSDIHMLETSDNARIRLNTKDEKLTVHKAYQGGADFLFGYDVRESDKP
ALTFEDKVSGKSGVVLERRPENLKTLDGRKLIAAEKADSNSFAFKQNYRQGLYELLLKQCEGGFCLGVQRLAIPEAEAVL
YAQQAYAANTLFGLRAADRGDDVYAADPSRQKLWLRFIGGRSHQNIRGGAAADGRRKGVQIGGEVFVRQNEGSRLAIGVM
GGRAGQHASVNGKGGAAGSYLYGYGGGVYAAWHQLRDKQTGAYLDGWLQYQRFKHRINDENRAERYKTKGWTASVEGGYN
ALVAEGIVGKGNNVRFYLQPQAQFTYLGVNGGFTDSEGTAVGLLGSGQWQSRAGIRAKTRFALRNGVNLQPFAAFNVLHR
SKSFGVEMDGEKQTLAGRTALEGRFGIEAGWKGHMSARIGYGKRTDGDKEAALSLKWLF

Sequences:

>Translated_619_residues
MFRAQLGSNTRSTKIGDDADFSFSDKPKPGTSHYFSSGKTDQNSSEYGYDEINIQGKNYNSGILAVDNMPVVKKYITDTY
GDNLKDAVKKQLQDLYKTRPEAWEENKKRTEEAYIEQLGPKFSILKQKNPDLINKLVEDSVLTPHSNTSQTSLNNIFNKK
LHVKIENKSHVAGQVLELTKMTLKDSLWEPRRHSDIHMLETSDNARIRLNTKDEKLTVHKAYQGGADFLFGYDVRESDKP
ALTFEDKVSGKSGVVLERRPENLKTLDGRKLIAAEKADSNSFAFKQNYRQGLYELLLKQCEGGFCLGVQRLAIPEAEAVL
YAQQAYAANTLFGLRAADRGDDVYAADPSRQKLWLRFIGGRSHQNIRGGAAADGRRKGVQIGGEVFVRQNEGSRLAIGVM
GGRAGQHASVNGKGGAAGSYLYGYGGGVYAAWHQLRDKQTGAYLDGWLQYQRFKHRINDENRAERYKTKGWTASVEGGYN
ALVAEGIVGKGNNVRFYLQPQAQFTYLGVNGGFTDSEGTAVGLLGSGQWQSRAGIRAKTRFALRNGVNLQPFAAFNVLHR
SKSFGVEMDGEKQTLAGRTALEGRFGIEAGWKGHMSARIGYGKRTDGDKEAALSLKWLF
>Mature_619_residues
MFRAQLGSNTRSTKIGDDADFSFSDKPKPGTSHYFSSGKTDQNSSEYGYDEINIQGKNYNSGILAVDNMPVVKKYITDTY
GDNLKDAVKKQLQDLYKTRPEAWEENKKRTEEAYIEQLGPKFSILKQKNPDLINKLVEDSVLTPHSNTSQTSLNNIFNKK
LHVKIENKSHVAGQVLELTKMTLKDSLWEPRRHSDIHMLETSDNARIRLNTKDEKLTVHKAYQGGADFLFGYDVRESDKP
ALTFEDKVSGKSGVVLERRPENLKTLDGRKLIAAEKADSNSFAFKQNYRQGLYELLLKQCEGGFCLGVQRLAIPEAEAVL
YAQQAYAANTLFGLRAADRGDDVYAADPSRQKLWLRFIGGRSHQNIRGGAAADGRRKGVQIGGEVFVRQNEGSRLAIGVM
GGRAGQHASVNGKGGAAGSYLYGYGGGVYAAWHQLRDKQTGAYLDGWLQYQRFKHRINDENRAERYKTKGWTASVEGGYN
ALVAEGIVGKGNNVRFYLQPQAQFTYLGVNGGFTDSEGTAVGLLGSGQWQSRAGIRAKTRFALRNGVNLQPFAAFNVLHR
SKSFGVEMDGEKQTLAGRTALEGRFGIEAGWKGHMSARIGYGKRTDGDKEAALSLKWLF

Specific function: Unknown

COG id: COG3468

COG function: function code MU; Type V secretory pathway, adhesin AidA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

Organism=Escherichia coli, GI1788565, Length=254, Percent_Identity=29.9212598425197, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR006315
- InterPro:   IPR012332
- InterPro:   IPR011050
- InterPro:   IPR004899 [H]

Pfam domain/function: PF03797 Autotransporter; PF03212 Pertactin [H]

EC number: NA

Molecular weight: Translated: 68696; Mature: 68696

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRAQLGSNTRSTKIGDDADFSFSDKPKPGTSHYFSSGKTDQNSSEYGYDEINIQGKNYN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCC
SGILAVDNMPVVKKYITDTYGDNLKDAVKKQLQDLYKTRPEAWEENKKRTEEAYIEQLGP
CCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KFSILKQKNPDLINKLVEDSVLTPHSNTSQTSLNNIFNKKLHVKIENKSHVAGQVLELTK
CEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
MTLKDSLWEPRRHSDIHMLETSDNARIRLNTKDEKLTVHKAYQGGADFLFGYDVRESDKP
HHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCC
ALTFEDKVSGKSGVVLERRPENLKTLDGRKLIAAEKADSNSFAFKQNYRQGLYELLLKQC
CEEEHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
EGGFCLGVQRLAIPEAEAVLYAQQAYAANTLFGLRAADRGDDVYAADPSRQKLWLRFIGG
CCCEEEEEHHHCCCCHHHHEEHHHHHHHHHEEEEEECCCCCCEEECCCCHHEEEEEEECC
RSHQNIRGGAAADGRRKGVQIGGEVFVRQNEGSRLAIGVMGGRAGQHASVNGKGGAAGSY
CCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
LYGYGGGVYAAWHQLRDKQTGAYLDGWLQYQRFKHRINDENRAERYKTKGWTASVEGGYN
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCE
ALVAEGIVGKGNNVRFYLQPQAQFTYLGVNGGFTDSEGTAVGLLGSGQWQSRAGIRAKTR
EEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHH
FALRNGVNLQPFAAFNVLHRSKSFGVEMDGEKQTLAGRTALEGRFGIEAGWKGHMSARIG
HHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEC
YGKRTDGDKEAALSLKWLF
CCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MFRAQLGSNTRSTKIGDDADFSFSDKPKPGTSHYFSSGKTDQNSSEYGYDEINIQGKNYN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCC
SGILAVDNMPVVKKYITDTYGDNLKDAVKKQLQDLYKTRPEAWEENKKRTEEAYIEQLGP
CCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KFSILKQKNPDLINKLVEDSVLTPHSNTSQTSLNNIFNKKLHVKIENKSHVAGQVLELTK
CEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
MTLKDSLWEPRRHSDIHMLETSDNARIRLNTKDEKLTVHKAYQGGADFLFGYDVRESDKP
HHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCC
ALTFEDKVSGKSGVVLERRPENLKTLDGRKLIAAEKADSNSFAFKQNYRQGLYELLLKQC
CEEEHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
EGGFCLGVQRLAIPEAEAVLYAQQAYAANTLFGLRAADRGDDVYAADPSRQKLWLRFIGG
CCCEEEEEHHHCCCCHHHHEEHHHHHHHHHEEEEEECCCCCCEEECCCCHHEEEEEEECC
RSHQNIRGGAAADGRRKGVQIGGEVFVRQNEGSRLAIGVMGGRAGQHASVNGKGGAAGSY
CCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
LYGYGGGVYAAWHQLRDKQTGAYLDGWLQYQRFKHRINDENRAERYKTKGWTASVEGGYN
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCE
ALVAEGIVGKGNNVRFYLQPQAQFTYLGVNGGFTDSEGTAVGLLGSGQWQSRAGIRAKTR
EEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHH
FALRNGVNLQPFAAFNVLHRSKSFGVEMDGEKQTLAGRTALEGRFGIEAGWKGHMSARIG
HHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEC
YGKRTDGDKEAALSLKWLF
CCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]