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The map label for this gene is visC [H]

Identifier: 161870746

GI number: 161870746

Start: 1864381

End: 1865736

Strand: Direct

Name: visC [H]

Synonym: NMCC_1820

Alternate gene names: 161870746

Gene position: 1864381-1865736 (Clockwise)

Preceding gene: 161870745

Following gene: 161870747

Centisome position: 86.58

GC content: 50.81

Gene sequence:

>1356_bases
TTGATACACATTAAGCTGAAAGTAAAAATCCGCATACACCCTCCCCTGCATATTTCTTCAACAGTGGGTTTTGATATAAT
CGCCTATCTGTTACAGATAGTTCAAACGGCATTCAAACCCTTACAAATACCGTCTGAAATCATCGGCATCCGTCTATGCA
AAGGATATTTTATGAGTTTACACAGCGACATCCTCGTCGTCGGCGCAGGCCCGGCGGGTTTAAGTTTTGCAGCCGAACTT
GCCGGCAGCGGTTTGAAAGTTACCCTGATTGAACGCAGCCCACTGACTGTTCTGCAAAATCCTCCATATGACGGACGCGA
AATCGCCCTGACCCATTTTTCCCGCGAAATCATGCAGCGTTTGGGTATGTGGGACAAAATTCCCGAAAACGAAATCTACC
CTTTGCGCGATGCCAAAGTGCTGAACGGACGTTCCGACTACCAGCTCCACTTTCCCCAACCGACCGAGGCGCGCGGCGAA
CCTGCCGACTGTTTGGGCTATCTTATTTCCAACCACAATATCCGACGCGCTGCCTACGAAGTCGTATCCCAACTCGACAA
CATTACCATTCTGACCGATACGGTTGTCAAAGAAGTCAAAACATCTGACAACGAAGCACAAGTCATTTTGGAAAACGGCA
AAATCCTGACTGCACGCCTGCTTTTGGCGGCAGACAGCCGCTTCTCGCAAACCCGTCGACAACTCGGTATCTCCTCCGAT
ATGCACGATTACAGCCGAACCATGTTCGTCTGCCGTATGAAACATACCCTTTCCAACCAACATACCGCTTACGAATGCTT
CCATTACGGACGCACCATCGCACTGCTGCCGCTGGAAGAGCACCTGACCAATACCGTCATTACCGTCGATACCGATAAAA
TCAACAGCGTTCAAAACCTTTCGCCCGAAGAATTGGCGGCAAGCGTAAAAGAACAGCTCAAGGGCAGGCTTGGCGACATG
GAACTGGTCAGCAGTATCCACCATTACCCCCTTGTCGGTATGATTGCCAAACGTTTCTACGGTAAACGCAGCGCGCTGAT
CGGCGATGCGGCTGTCGGTATGCACCCCGTTACCGCACACGGTTTCAACTTGGGTCTGTCCAGCGCAGATATTTTGGCAA
AACTGATACTCGAAGCCGAGCAGCGCGGTCAGGACATCGGCGCGGCTTCCTTGTTGGAAAAATACAGCAGCAAACATATG
CTGCATGCCCAGCCGCTTTATCACGGAACCAATATGATGCTGAAACTGTTTACCAACGAAACCGCGCCGGCAAAACTGCT
GCGCGGTTTGGTATTGCGTGCCGGCAACAACTTCCCGCCGCTGAAAAAGCTGATTACCAAACAACTGACCGGTTGA

Upstream 100 bases:

>100_bases
TTGGTGCTTCAGCACCTTAGAGAATCGTTCTCTTTGAGCTAAGGCGAGGCAACGCCGTACTGGTTTAAATTTAATCCACT
ATACATACCCCACACCCGAT

Downstream 100 bases:

>100_bases
AAACTGCCGAAATGCCGTCTGAAACGTTTCAGACGGCATTTTTGTATTATAGTGGATTAACAAAAATCAGGACAAGGCGA
CGAAGCTGCAGACAGTACAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MIHIKLKVKIRIHPPLHISSTVGFDIIAYLLQIVQTAFKPLQIPSEIIGIRLCKGYFMSLHSDILVVGAGPAGLSFAAEL
AGSGLKVTLIERSPLTVLQNPPYDGREIALTHFSREIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGE
PADCLGYLISNHNIRRAAYEVVSQLDNITILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQLGISSD
MHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPLEEHLTNTVITVDTDKINSVQNLSPEELAASVKEQLKGRLGDM
ELVSSIHHYPLVGMIAKRFYGKRSALIGDAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGAASLLEKYSSKHM
LHAQPLYHGTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQLTG

Sequences:

>Translated_451_residues
MIHIKLKVKIRIHPPLHISSTVGFDIIAYLLQIVQTAFKPLQIPSEIIGIRLCKGYFMSLHSDILVVGAGPAGLSFAAEL
AGSGLKVTLIERSPLTVLQNPPYDGREIALTHFSREIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGE
PADCLGYLISNHNIRRAAYEVVSQLDNITILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQLGISSD
MHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPLEEHLTNTVITVDTDKINSVQNLSPEELAASVKEQLKGRLGDM
ELVSSIHHYPLVGMIAKRFYGKRSALIGDAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGAASLLEKYSSKHM
LHAQPLYHGTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQLTG
>Mature_451_residues
MIHIKLKVKIRIHPPLHISSTVGFDIIAYLLQIVQTAFKPLQIPSEIIGIRLCKGYFMSLHSDILVVGAGPAGLSFAAEL
AGSGLKVTLIERSPLTVLQNPPYDGREIALTHFSREIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGE
PADCLGYLISNHNIRRAAYEVVSQLDNITILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQLGISSD
MHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPLEEHLTNTVITVDTDKINSVQNLSPEELAASVKEQLKGRLGDM
ELVSSIHHYPLVGMIAKRFYGKRSALIGDAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGAASLLEKYSSKHM
LHAQPLYHGTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQLTG

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=411, Percent_Identity=25.3041362530414, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI32967307, Length=332, Percent_Identity=26.2048192771084, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789273, Length=393, Percent_Identity=28.498727735369, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789274, Length=400, Percent_Identity=24.75, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786883, Length=391, Percent_Identity=23.5294117647059, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25146631, Length=452, Percent_Identity=23.6725663716814, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321694, Length=464, Percent_Identity=26.5086206896552, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19920760, Length=422, Percent_Identity=24.6445497630332, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 50107; Mature: 50107

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHIKLKVKIRIHPPLHISSTVGFDIIAYLLQIVQTAFKPLQIPSEIIGIRLCKGYFMSL
CEEEEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
HSDILVVGAGPAGLSFAAELAGSGLKVTLIERSPLTVLQNPPYDGREIALTHFSREIMQR
CCCEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCEEHHHHHHHHHHHH
LGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGEPADCLGYLISNHNIRRAAYE
CCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
VVSQLDNITILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQLGISSD
HHHHHCCEEEEHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHCHHHHHHHHHHCCCCC
MHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPLEEHLTNTVITVDTDKINSVQNL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECHHHHCCCEEEEECHHCCHHHCC
SPEELAASVKEQLKGRLGDMELVSSIHHYPLVGMIAKRFYGKRSALIGDAAVGMHPVTAH
CHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCHHCCCCCEEEC
GFNLGLSSADILAKLILEAEQRGQDIGAASLLEKYSSKHMLHAQPLYHGTNMMLKLFTNE
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCHHCCCCEEEEEECCC
TAPAKLLRGLVLRAGNNFPPLKKLITKQLTG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIHIKLKVKIRIHPPLHISSTVGFDIIAYLLQIVQTAFKPLQIPSEIIGIRLCKGYFMSL
CEEEEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
HSDILVVGAGPAGLSFAAELAGSGLKVTLIERSPLTVLQNPPYDGREIALTHFSREIMQR
CCCEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCEEHHHHHHHHHHHH
LGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGEPADCLGYLISNHNIRRAAYE
CCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
VVSQLDNITILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQLGISSD
HHHHHCCEEEEHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHCHHHHHHHHHHCCCCC
MHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPLEEHLTNTVITVDTDKINSVQNL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECHHHHCCCEEEEECHHCCHHHCC
SPEELAASVKEQLKGRLGDMELVSSIHHYPLVGMIAKRFYGKRSALIGDAAVGMHPVTAH
CHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCHHCCCCCEEEC
GFNLGLSSADILAKLILEAEQRGQDIGAASLLEKYSSKHMLHAQPLYHGTNMMLKLFTNE
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCHHCCCCEEEEEECCC
TAPAKLLRGLVLRAGNNFPPLKKLITKQLTG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]