Click here to switch to the map view.

The map label for this gene is dtd [H]

Identifier: 161870722

GI number: 161870722

Start: 1842579

End: 1843034

Strand: Reverse

Name: dtd [H]

Synonym: NMCC_1795

Alternate gene names: 161870722

Gene position: 1843034-1842579 (Counterclockwise)

Preceding gene: 161870723

Following gene: 161870721

Centisome position: 85.59

GC content: 57.02

Gene sequence:

>456_bases
GTGGATGTCGTGTCCGAAGCCGGCACGGAAACCTGTGGCAAAATCGACGGCGGGTTTGTCGTGTTACTCGGCGTAACGCA
TAGCGACACAGAAAAAGATGCACGCTATATCGCCGACAAAATCGCCCATTTGCGCGTGTTTGAAGACGAAGCGGGCAAGC
TGAACCTGTCTTTGAAAGATGTCGGCGGCGCGGTGCTGCTGGTGTCGCAGTTTACGCTTTATGCCGACGCGGCAAGCGGG
CGGCGGCCTTCGTTTTCGCAAGCCGCACCTGCAGAACAGGCGCAGCAGCTTTACCTGCGAACGGCGGAACTGTTGCGCGG
GCACGGGATTCATGTCGAAACAGGGCGTTTCCGCACGCATATGCAGGTGTCGCTCTGTAACGACGGGCCGGTAACCATAC
TGCTGGACTCTTTCATGACGCGGATTTCCCCAAAAATGAAGGTTGTTCCGGATTGA

Upstream 100 bases:

>100_bases
CAATACCGATGCCGTCTGAAGCCTTTTCAGACGGCATTGCACGTTCAGGTAAGGAGGACGGCTTATGCGTGCGGTCATAC
AGAAAACGGTAGGTGCAAAG

Downstream 100 bases:

>100_bases
AATTGAATCCGCAATGGTGAAATATCGACAATGAACGACAACACGCAAACCCTTCCCCCACGCCGCCTGTCCGTCGCCCC
GATGCTCGACTGGACGGACA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASG
RRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKVVPD

Sequences:

>Translated_151_residues
MDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASG
RRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKVVPD
>Mature_151_residues
MDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASG
RRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKVVPD

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=133, Percent_Identity=42.8571428571429, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790320, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI115533292, Length=133, Percent_Identity=38.3458646616541, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319982, Length=132, Percent_Identity=36.3636363636364, Blast_Score=85, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281361569, Length=130, Percent_Identity=41.5384615384615, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16388; Mature: 16388

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEHH
VGGAVLLVSQFTLYADAASGRRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTH
CCCEEEEEEHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEE
MQVSLCNDGPVTILLDSFMTRISPKMKVVPD
EEEEEECCCCEEEEHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEHH
VGGAVLLVSQFTLYADAASGRRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTH
CCCEEEEEEHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEE
MQVSLCNDGPVTILLDSFMTRISPKMKVVPD
EEEEEECCCCEEEEHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA