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The map label for this gene is lptA [H]

Identifier: 161870714

GI number: 161870714

Start: 1836304

End: 1836774

Strand: Reverse

Name: lptA [H]

Synonym: NMCC_1787

Alternate gene names: 161870714

Gene position: 1836774-1836304 (Counterclockwise)

Preceding gene: 161870715

Following gene: 161870713

Centisome position: 85.3

GC content: 53.93

Gene sequence:

>471_bases
TTGCCCCTTCAAAGCGACAGCAGGCAGCCTATTCAGATTGAGGCCGACCAAGGTTCGCTCAATCAAGCCAACCAAAGCAC
TACATTTAGCGGAAACGTTGTCATCAGACAGGGTACGCTCAATATTTCCGCCGCCCGCGTCAACGTAACGCGTAATGACA
AAGGCGAACAGTTTATGAAGGCCGACGGCTCGCCCGTACGCTTCAGCCAAACGTTGGACGGGGGCAAAGGGACGGTGCGC
GGTCAGGCAAACAACGTTGCTTATTCGTCTGCAGGCAGCACCGTAGTCTTAACCGGTAATGCCAAAGTACAGCGCGGCGG
CGATGTCGCCGAAGGCGCGGTGATTACATACAACACCAAAACCGAAGTCTATACCATCAGCGGCAGTACAAAATCCGGCG
CAAAATCCGCTTCCAAATCCGGCAGGGTCAGCGTCATCATCCAGCCTTCGAGTACGCAAAAATCCGAATAA

Upstream 100 bases:

>100_bases
GCATGTTGAACTTCTCATCTAAAGTGAAAGCCACGATTTATGATACAAAAGATATGTAAGCTATTTGTTTTAATAGCATT
TTTTTCGGCGTCCCCCGCTT

Downstream 100 bases:

>100_bases
TCCCAAAATGCCGTCTGAAACATAAACCCGGTTCCGACGGCATATGCCGACCGAAGATATTGAAGAGATATTTATGAGCG
CAAACGTCAGCCGCCTTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MPLQSDSRQPIQIEADQGSLNQANQSTTFSGNVVIRQGTLNISAARVNVTRNDKGEQFMKADGSPVRFSQTLDGGKGTVR
GQANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTKTEVYTISGSTKSGAKSASKSGRVSVIIQPSSTQKSE

Sequences:

>Translated_156_residues
MPLQSDSRQPIQIEADQGSLNQANQSTTFSGNVVIRQGTLNISAARVNVTRNDKGEQFMKADGSPVRFSQTLDGGKGTVR
GQANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTKTEVYTISGSTKSGAKSASKSGRVSVIIQPSSTQKSE
>Mature_155_residues
PLQSDSRQPIQIEADQGSLNQANQSTTFSGNVVIRQGTLNISAARVNVTRNDKGEQFMKADGSPVRFSQTLDGGKGTVRG
QANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTKTEVYTISGSTKSGAKSASKSGRVSVIIQPSSTQKSE

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=150, Percent_Identity=39.3333333333333, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 16242; Mature: 16111

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQSDSRQPIQIEADQGSLNQANQSTTFSGNVVIRQGTLNISAARVNVTRNDKGEQFMK
CCCCCCCCCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEEEEEEEEEECCCCCEEEC
ADGSPVRFSQTLDGGKGTVRGQANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTK
CCCCEEEEEEECCCCCEEEEECCCCEEEECCCCEEEEECCCEEECCCCCCCCEEEEECCC
TEVYTISGSTKSGAKSASKSGRVSVIIQPSSTQKSE
EEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
PLQSDSRQPIQIEADQGSLNQANQSTTFSGNVVIRQGTLNISAARVNVTRNDKGEQFMK
CCCCCCCCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEEEEEEEEEECCCCCEEEC
ADGSPVRFSQTLDGGKGTVRGQANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVITYNTK
CCCCEEEEEEECCCCCEEEEECCCCEEEECCCCEEEEECCCEEECCCCCCCCEEEEECCC
TEVYTISGSTKSGAKSASKSGRVSVIIQPSSTQKSE
EEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]