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The map label for this gene is thiL [H]

Identifier: 161870686

GI number: 161870686

Start: 1809699

End: 1810544

Strand: Reverse

Name: thiL [H]

Synonym: NMCC_1758

Alternate gene names: 161870686

Gene position: 1810544-1809699 (Counterclockwise)

Preceding gene: 161870687

Following gene: 161870685

Centisome position: 84.08

GC content: 55.67

Gene sequence:

>846_bases
TTGTGTTTCAGTGCGGATATGCTTTTGAAGGACAGGCATTTTTTTGCAGATGTCAAACCTGAAGACTTGGCTTGGAAGGT
TTTGGCCGTCAATATTTCAGATATGGCGGCGATGGGCGCGATACCGCGTTGGGTGCTGCTGAGCGCGGCGTTGCCCGAAT
TGGATGAAGTATGGCTGGAACGGTTTTGCGGCAGCTTTTTCGGTTTGGCAAAAAAGTTTGGCGTAACGTTAATCGGCGGA
GATACGACCAAGGGCGATATGGCGTTCAATGTAACCATTATCGGCGAATTGCCGAAGGGTAGGGCATTGCGGCGTGATGC
GGCGGTTGCGGGTGACGATATTTGGGTGTCGGGGCGTGTCGGTATGGCGGCGGCGGCTTTGAACTGCCGTCTGAAACGGT
GTGTGTTGCCGGATGATGTGTTTGCCGAATGCGAACAAAAGCTGCTCCGCCCCGAGCCAAGGGTTGGGCTGGGGCTTGCG
CTGTTGCCGTTTGCCCGGGCGGCGCAGGATGTTTCAGACGGCCTCGCGCAAGATTTGGGGCATATCCTGACCGCTTCCGG
CGTGGGGGCGGAAATTTGGGCCGATTCGCTGCCGTCTTTATCCGTATTGAAAGATATTTTGCCCCGAGCGCAATGGCTGT
CTTATACTTTGGCGGGCGGCGACGATTACGAGCTGGTGTTTACCGCGCCGGAAAGTTGCCGCAGCCGCGTGCTTGATGCG
GCAGAACGGTGCGGCGTGCCGGTAACGCGCATCGGCAAAATCAACGGAGGATGCCGTCTGAAGGTTTTAGATGCTGACGG
CAGGGAATTGGAACTACATTCTTTAGGATTCGATCATTTTGGCTGA

Upstream 100 bases:

>100_bases
CGACTTCATCAAACGGTATTTGCAAACAGGCACGGATAAGGATGTCGTATTGGGCATAGGCGACGATGCGGCGATTGTCC
GTCCGCGTGAAGGCTTCGAT

Downstream 100 bases:

>100_bases
TTTTAAACCTGACTTTGCGTGGCTGTTGAAACGACCGTTGTGTTTTTTGGCTTTTGGTTTCGGCAGCGGGCTGGCTCCGT
TCGCGCCGGGTACATTTGGC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLERFCGSFFGLAKKFGVTLIGG
DTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLA
LLPFARAAQDVSDGLAQDLGHILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA
AERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG

Sequences:

>Translated_281_residues
MCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLERFCGSFFGLAKKFGVTLIGG
DTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLA
LLPFARAAQDVSDGLAQDLGHILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA
AERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG
>Mature_281_residues
MCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLERFCGSFFGLAKKFGVTLIGG
DTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLA
LLPFARAAQDVSDGLAQDLGHILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA
AERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=281, Percent_Identity=43.0604982206406, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 30357; Mature: 30357

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLE
CCCCCCHHHHCCHHCCCCCCCCCEEEEEEEEHHHHHHHCCCHHHHHHHHCCCHHHHHHHH
RFCGSFFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRV
HHHHHHHHHHHHHCEEEECCCCCCCCEEEEEEEEEECCCCCCHHHHCCCCCCCEEEECCC
GMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLPFARAAQDVSDGLAQDLG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA
HHHHCCCCCHHHHHCCCCCHHHHHHHHCHHHHHEEEECCCCCEEEEEECCHHHHHHHHHH
AERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG
HHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MCFSADMLLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLE
CCCCCCHHHHCCHHCCCCCCCCCEEEEEEEEHHHHHHHCCCHHHHHHHHCCCHHHHHHHH
RFCGSFFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRV
HHHHHHHHHHHHHCEEEECCCCCCCCEEEEEEEEEECCCCCCHHHHCCCCCCCEEEECCC
GMAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLPFARAAQDVSDGLAQDLG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA
HHHHCCCCCHHHHHCCCCCHHHHHHHHCHHHHHEEEECCCCCEEEEEECCHHHHHHHHHH
AERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG
HHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]