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The map label for this gene is galM [H]

Identifier: 161870682

GI number: 161870682

Start: 1804728

End: 1805738

Strand: Reverse

Name: galM [H]

Synonym: NMCC_1754

Alternate gene names: 161870682

Gene position: 1805738-1804728 (Counterclockwise)

Preceding gene: 161870683

Following gene: 161870681

Centisome position: 83.85

GC content: 62.31

Gene sequence:

>1011_bases
ATGAGCGATACCCCCGCTACCCGCGATTTCGGTCTGATCGACGGGCGTGCCGTAACCGGCTATGTGCTGTCCAACCGGCG
TGGTACGCGTGTCTGCGTGCTGGACTTGGGCGGGATTGTGCAGGAATTTTCCGTTTTGGCAGACGGCGTGCGCGAAAACC
TCGTGGTGTCGTTCGATGATGCGGCTTCCTATGCGGACAATCCGTTTCAGATTAACAAACAGATAGGGCGCGTGGCCGGA
CGCATCCGCGGTGCGGCGTTCGACATCAACGGCAGGACTTACCGCGTGGAGGCCAACGAAGGCAGGAACGCGCTGCACGG
CGGTTCGCACGGGCTGGCCGTTACCCGTTTCAACGCGGTGGCGGCAGACGGCCGTTCGGTGGTGCTGCGCAGCCGCCTGC
AACAGTCGGCCGACGGTTATCCCAACGATTTGGATTTGGATATTTCCTACCGCTTGGACGAGGACGACCGGCTTACCGTT
ACCTATCGCGCCACCGCGCTCGGCGACACGGTGTTCGACCCGACGCTGCACATTTACTGGCGGCTGGACGCGGGCCTGCA
CGATGCGGTTCTGCATATTCCGCAGGGCGGACATATTCCGGCCGATGCCGAAAAACTGCCCGTCTCAACGGTTTCAGACG
GCCTCGAAGTATTTGATTTCAGCCGGCCCAAGCCGCTGGATGCCGCCGTTGCCGCCCTGCGCCGCGAAACGGGTCGGGCC
GGTTTTGACGACGCTTACCGCGTGCCGTCCGATATAGGCCGTCCCGCCGCTGTGTTGCAAGCCGGACGCCGCTGTCGTAT
CAGCATATACAGCGACCGCAACGGCTTGGTCATCTTTACCGCCGCCCCGCAGGATTTCGCGCGGCACGATGCGGGCGTTT
ACGACGCGCTGGCGACCGAGGCGCAGACGCTGCCCGACAGCCTGCATTGGCCCGAGTTCGGCAATATTCGTCTGAACAAG
GGTGATACCAGGGAGGCGACGATTGCTTACGGCATCGAATCCCTTTCTTAG

Upstream 100 bases:

>100_bases
CGGTTTGCAGGCCAATATGTTCTTGGTAGGGGGCGTCGTCCTGCTGCTGGGCGCGTTTTCCGTGTTCCTGATTAAAGAAA
CACACGGCGGGGTTTGAGCG

Downstream 100 bases:

>100_bases
GAGCTTCCTAACACCGGTTGCAGACGGCCTTTTTATAGTGGATTAACAAAAACCAGTACGGCGTTGCCTCGCCTTAGCTC
AAAGAGAACGATTCTCTAAG

Product: aldose 1-epimerase (mutarotase)

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFSVLADGVRENLVVSFDDAASYADNPFQINKQIGRVAG
RIRGAAFDINGRTYRVEANEGRNALHGGSHGLAVTRFNAVAADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTV
TYRATALGDTVFDPTLHIYWRLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDGLEVFDFSRPKPLDAAVAALRRETGRA
GFDDAYRVPSDIGRPAAVLQAGRRCRISIYSDRNGLVIFTAAPQDFARHDAGVYDALATEAQTLPDSLHWPEFGNIRLNK
GDTREATIAYGIESLS

Sequences:

>Translated_336_residues
MSDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFSVLADGVRENLVVSFDDAASYADNPFQINKQIGRVAG
RIRGAAFDINGRTYRVEANEGRNALHGGSHGLAVTRFNAVAADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTV
TYRATALGDTVFDPTLHIYWRLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDGLEVFDFSRPKPLDAAVAALRRETGRA
GFDDAYRVPSDIGRPAAVLQAGRRCRISIYSDRNGLVIFTAAPQDFARHDAGVYDALATEAQTLPDSLHWPEFGNIRLNK
GDTREATIAYGIESLS
>Mature_335_residues
SDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFSVLADGVRENLVVSFDDAASYADNPFQINKQIGRVAGR
IRGAAFDINGRTYRVEANEGRNALHGGSHGLAVTRFNAVAADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTVT
YRATALGDTVFDPTLHIYWRLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDGLEVFDFSRPKPLDAAVAALRRETGRAG
FDDAYRVPSDIGRPAAVLQAGRRCRISIYSDRNGLVIFTAAPQDFARHDAGVYDALATEAQTLPDSLHWPEFGNIRLNKG
DTREATIAYGIESLS

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=320, Percent_Identity=25.3125, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1786971, Length=329, Percent_Identity=26.4437689969605, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17557428, Length=167, Percent_Identity=28.1437125748503, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115533334, Length=167, Percent_Identity=28.1437125748503, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24583720, Length=357, Percent_Identity=26.3305322128852, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24668278, Length=336, Percent_Identity=25, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24659048, Length=337, Percent_Identity=24.0356083086053, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668282, Length=334, Percent_Identity=24.5508982035928, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 36527; Mature: 36396

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFSVLADGVRENLVVSFDD
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECC
AASYADNPFQINKQIGRVAGRIRGAAFDINGRTYRVEANEGRNALHGGSHGLAVTRFNAV
HHCCCCCCEEEHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEEEE
AADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTVTYRATALGDTVFDPTLHIYW
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCCCCEEEEEE
RLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDGLEVFDFSRPKPLDAAVAALRRETGRA
EECCCCCEEEEECCCCCCCCCCHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCC
GFDDAYRVPSDIGRPAAVLQAGRRCRISIYSDRNGLVIFTAAPQDFARHDAGVYDALATE
CCCCCCCCCHHCCCCHHHHHCCCEEEEEEEECCCCEEEEEECCHHHHHHCCCHHHHHHHH
AQTLPDSLHWPEFGNIRLNKGDTREATIAYGIESLS
HHHCCCCCCCCCCCCEEECCCCCCCEEEEECHHHCC
>Mature Secondary Structure 
SDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFSVLADGVRENLVVSFDD
CCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECC
AASYADNPFQINKQIGRVAGRIRGAAFDINGRTYRVEANEGRNALHGGSHGLAVTRFNAV
HHCCCCCCEEEHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEEEE
AADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTVTYRATALGDTVFDPTLHIYW
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCCCCEEEEEE
RLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDGLEVFDFSRPKPLDAAVAALRRETGRA
EECCCCCEEEEECCCCCCCCCCHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCC
GFDDAYRVPSDIGRPAAVLQAGRRCRISIYSDRNGLVIFTAAPQDFARHDAGVYDALATE
CCCCCCCCCHHCCCCHHHHHCCCEEEEEEEECCCCEEEEEECCHHHHHHCCCHHHHHHHH
AQTLPDSLHWPEFGNIRLNKGDTREATIAYGIESLS
HHHCCCCCCCCCCCCEEECCCCCCCEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1694527 [H]